KR940014360A - 1,4-벤즈옥사진 유도체 - Google Patents

1,4-벤즈옥사진 유도체 Download PDF

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Publication number
KR940014360A
KR940014360A KR1019930026059A KR930026059A KR940014360A KR 940014360 A KR940014360 A KR 940014360A KR 1019930026059 A KR1019930026059 A KR 1019930026059A KR 930026059 A KR930026059 A KR 930026059A KR 940014360 A KR940014360 A KR 940014360A
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KR
South Korea
Prior art keywords
group
substituted
lower alkyl
atom
hydrogen atom
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KR1019930026059A
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English (en)
Inventor
가즈오 야마자키
시게루 아데가와
요이치로 오가와
히데아키 마츠다
타다유키 구라이시
Original Assignee
타이도 나오카타
에스에스 세이야쿠 가부시키가이샤
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Publication of KR940014360A publication Critical patent/KR940014360A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

다음의 일반식(Ⅰ)
(식중, R1은 비치환 또는 할로겐으로 치환된 저급 알킬기, 비치환 또는 할로겐으로 치환된 저급알킬술포닐기, 니트로기 또는 시아노기를 나타내고, R2및 R3는 서로 같거나 다른 것으로써, 수소원자 또는 저급알킬기를 나타내거나, 인접탄소와 결합하여 3~6환을 나타내며, R4는 수소원자 또는 치환되어 있어도 좋은 저급알킬기 또는 아실기를 나타내고, R5는 수소원자 또는 치환되어 있어도 좋은 저급 알킬기, 저급알케닐기, 저급알콕시기, 아릴기, 아릴옥시기 또는 복소환기를 나타내며, Y는 산소 또는 황원자를 나타내며, 다만, R2및 R3가 각각 메틸기이고, R4는 수소원자이며, R3가 3-클로로프로필기이고, Y가 산소원자일 때, R1은 니트로기 또는 시아노기가 아니다)로 표시되는 1,4-벤즈옥사진 유도체 또는 그 염을 개시한다.

Description

1,4-벤즈옥사진 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 다음의 일반식(Ⅰ)
    (식중, R1은 비치환 또는 할로겐으로 치환된 저급 알킬기, 비치환 또는 할로겐으로 치환된 저급알킬술포닐기, 니트로기 또는 시아노기를 나타내고, R2및 R3는 서로 같거나 다른 것으로써, 수소원자 또는 저급알킬기를 나타내거나, 인접탄소와 결합하여 3~6환을 나타내며, R4는 수소원자 또는 치환되어 있어더 좋은 저급알킬기 또는 아실기를 나타내고, R5는 수소원자 또는 치환되어 있어도 좋은 저급 알킬기, 저급알케닐기, 저급알콕시기, 아릴기, 아릴옥시기 또는 복소환기를 나타내며, Y는 산소 또는 황원자를 나타내며, 다만, R2및 R3가 각각 메틸기이고, R4는 수소원자이며, R3가 3-클로로프로필기이고, Y가 산소원자일 때, R1은 니트로기 또는 시아노기가 아니다)로 표시되는 1,4-벤즈옥사진 유도체 또는 그 염.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930026059A 1992-12-03 1993-12-01 1,4-벤즈옥사진 유도체 KR940014360A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP32432992 1992-12-03
JP324329/1992 1992-12-03
JP5095925A JPH06220029A (ja) 1992-12-03 1993-04-22 １，４−ベンズオキサジン誘導体
JP95925/1993 1993-04-22

Publications (1)

Publication Number Publication Date
KR940014360A true KR940014360A (ko) 1994-07-18

Family

ID=26437092

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930026059A KR940014360A (ko) 1992-12-03 1993-12-01 1,4-벤즈옥사진 유도체

Country Status (7)

Country Link
US (1) US5440036A (ko)
EP (1) EP0602458A1 (ko)
JP (1) JPH06220029A (ko)
KR (1) KR940014360A (ko)
CN (1) CN1037179C (ko)
CA (1) CA2110520A1 (ko)
TW (1) TW360642B (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01209503A (ja) * 1988-02-17 1989-08-23 Fanuc Ltd Ｐｃの軸制御方式
WO2000012492A1 (en) * 1998-09-01 2000-03-09 Nissan Chemical Industries, Ltd. Benzoxazine derivatives
WO2011073276A1 (en) * 2009-12-16 2011-06-23 Evotec Ag Benzoxazine aryl sulfonamide derivatives as kv1.3 modulators
WO2011073273A1 (en) * 2009-12-16 2011-06-23 Evotec Ag Benzoxazine aryl sulfonamide derivatives as kv1.3 modulators
CN104130204B (zh) * 2014-07-03 2016-04-27 浙江大学 一种制备n-磺酰基-1,4-噁嗪类衍生物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63270678A (ja) * 1987-04-30 1988-11-08 Mitsui Petrochem Ind Ltd 新規含窒素化合物
TW224941B (ko) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd
CA2035147A1 (en) * 1990-02-08 1991-08-09 Kousuke Yasuda Thiazine (or oxazine) derivatives and preparation thereof

Also Published As

Publication number Publication date
TW360642B (en) 1999-06-11
JPH06220029A (ja) 1994-08-09
US5440036A (en) 1995-08-08
CN1095064A (zh) 1994-11-16
CN1037179C (zh) 1998-01-28
CA2110520A1 (en) 1994-06-04
EP0602458A1 (en) 1994-06-22

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