KR930701996A - 개에서의 기생충 치료를 위한 아베르멕틴 및 밀베마이신 - Google Patents
개에서의 기생충 치료를 위한 아베르멕틴 및 밀베마이신Info
- Publication number
- KR930701996A KR930701996A KR1019930701469A KR930701469A KR930701996A KR 930701996 A KR930701996 A KR 930701996A KR 1019930701469 A KR1019930701469 A KR 1019930701469A KR 930701469 A KR930701469 A KR 930701469A KR 930701996 A KR930701996 A KR 930701996A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- substituted
- optionally
- hydrogen
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
아베르멕틴 및 밀베마이신은 개에서의 내부-및 외부기생체 감염의 치료에 유용하다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (13)
- 개에서의 내부 및 외부기생체 감염의 치료 또는 예방을 위한 약.
- 제 제조를 위한 일반식(I)의 화합물의 이용 :
-
- 이때, R1은 수소 또는 임의로 보호된 히드록시이고, R2는 알콕시, 임의로 보호된 히드록시, 옥소 또는 임의 0-치환 옥시미노이고; R3는 수소, 임의로 보호된 히드록시, 또는 기 4'(α-L-올레안드로실)-α-L-올레안드로실옥시 또는α-L-올레안드로실옥시이며, 이때 말단 히드록시 기는 임의로 보호될 수 있고; R4,R5,R6및 R7은 동일하거나 상이하고 각각은 수소 또는 유기 라디칼이고; R8은 임의로 치환된 아미노 또는 아미노기 예컨대 임의 0-치환 옥시미노, 임의 N-치환 히드라존, 또는 임의 N-치환 세미카바존이며; 단, 일반식(I)의 화합물은 EP-A-0 307 220에서 공개된 화합물 또는 화합물(E)는 (F)가 아니다.
- 제1항에 있어서, 회충, 십이지장충, 편충 및/또는 모낭충 옴의 치료를 위한 이용.
- 제1항에 있어서, 사상충 감염의 예방을 위한 이용.
- 제1 내지 3항중 어느 한 항에 있어서, R1,R3,R4,R5및 R6가 수소이고, R2가 히드록시이고, R7이 t-부틸이고 R5이 메톡시이미노 또는 t-부틸옥시아미노 (E-또는 Z-이성질체 또는 그의 혼합물)인 이용.
- 제1항에서 정의된 바와같은 일반식(I)의 화합물의 비독성 유효량을 그를 필요로 하는 개에게 투여하는 것으로 구성되는, 개에서의 내부-및 외부기생체 감염의 치료 또는 예방 방법.
- 제1항에서 정의된 바와같은 일반식(I)의 화합물 및 제약학적으로 허용가능한 부형제로 구성되는, 개에서의 내부-및 외부기생체 감염의 치료에 사용하기 위한 제약학적 조성물.
- 제6항에 있어서, 구강 배합물의 형태인 조성물.
- 제6항에 있어서, 주사용 배합물의 형태인 조성물.
- 제6항에 있어서, 붓기 배합물의 형태인 조성물.
- ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9024927.7 | 1990-11-16 | ||
GB909024927A GB9024927D0 (en) | 1990-11-16 | 1990-11-16 | Novel treatment |
PCT/GB1991/001981 WO1992008455A1 (en) | 1990-11-16 | 1991-11-11 | Avermectins and milbemycins to treat parasitic in dogs |
Publications (1)
Publication Number | Publication Date |
---|---|
KR930701996A true KR930701996A (ko) | 1993-09-08 |
Family
ID=10685475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019930701469A KR930701996A (ko) | 1990-11-16 | 1991-11-11 | 개에서의 기생충 치료를 위한 아베르멕틴 및 밀베마이신 |
Country Status (15)
Country | Link |
---|---|
US (1) | US5643886A (ko) |
EP (1) | EP0557348B1 (ko) |
JP (1) | JP3009463B2 (ko) |
KR (1) | KR930701996A (ko) |
AT (1) | ATE165509T1 (ko) |
AU (2) | AU660429B2 (ko) |
CA (1) | CA2096345C (ko) |
DE (1) | DE69129334T2 (ko) |
DK (1) | DK0557348T3 (ko) |
ES (1) | ES2114893T3 (ko) |
GB (1) | GB9024927D0 (ko) |
IE (1) | IE913971A1 (ko) |
NZ (1) | NZ240588A (ko) |
WO (1) | WO1992008455A1 (ko) |
ZA (1) | ZA919021B (ko) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2753377B1 (fr) * | 1996-09-19 | 1999-09-24 | Rhone Merieux | Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides |
DE102004053964A1 (de) | 2004-11-09 | 2006-05-11 | Bayer Healthcare Ag | Mittel gegen Demodikose |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916153A (en) * | 1986-03-12 | 1990-04-10 | American Cyanamid Company | Macrolid compounds |
EP0260537A1 (en) * | 1986-09-12 | 1988-03-23 | American Cyanamid Company | 13-Deoxy-23-oxo(keto) and 23-imino derivatives of 13-deoxy C-076-aglycone compounds |
US4849446A (en) * | 1986-09-12 | 1989-07-18 | American Cyanamid Company | 23-imino derivatives of 23-keto compounds |
ES2058082T3 (es) * | 1986-09-12 | 1994-11-01 | American Cyanamid Co | Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249. |
NZ233680A (en) * | 1989-05-17 | 1995-02-24 | Beecham Group Plc | Avermectins and milbemycins and compositions thereof |
-
1990
- 1990-11-16 GB GB909024927A patent/GB9024927D0/en active Pending
-
1991
- 1991-11-11 KR KR1019930701469A patent/KR930701996A/ko not_active Application Discontinuation
- 1991-11-11 AU AU88658/91A patent/AU660429B2/en not_active Ceased
- 1991-11-11 JP JP3518006A patent/JP3009463B2/ja not_active Expired - Fee Related
- 1991-11-11 WO PCT/GB1991/001981 patent/WO1992008455A1/en active IP Right Grant
- 1991-11-11 DK DK91919873T patent/DK0557348T3/da active
- 1991-11-11 EP EP91919873A patent/EP0557348B1/en not_active Expired - Lifetime
- 1991-11-11 AT AT91919873T patent/ATE165509T1/de not_active IP Right Cessation
- 1991-11-11 US US08/064,080 patent/US5643886A/en not_active Expired - Fee Related
- 1991-11-11 DE DE69129334T patent/DE69129334T2/de not_active Expired - Fee Related
- 1991-11-11 ES ES91919873T patent/ES2114893T3/es not_active Expired - Lifetime
- 1991-11-11 CA CA002096345A patent/CA2096345C/en not_active Expired - Fee Related
- 1991-11-14 IE IE397191A patent/IE913971A1/en not_active IP Right Cessation
- 1991-11-14 NZ NZ240588A patent/NZ240588A/en unknown
- 1991-11-14 ZA ZA919021A patent/ZA919021B/xx unknown
-
1995
- 1995-09-29 AU AU32954/95A patent/AU688105B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
CA2096345C (en) | 2000-10-31 |
ZA919021B (en) | 1992-09-30 |
AU3295495A (en) | 1995-11-30 |
IE913971A1 (en) | 1992-05-20 |
EP0557348B1 (en) | 1998-04-29 |
AU8865891A (en) | 1992-06-11 |
GB9024927D0 (en) | 1991-01-02 |
ATE165509T1 (de) | 1998-05-15 |
CA2096345A1 (en) | 1992-05-17 |
JP3009463B2 (ja) | 2000-02-14 |
JPH06502405A (ja) | 1994-03-17 |
WO1992008455A1 (en) | 1992-05-29 |
US5643886A (en) | 1997-07-01 |
AU688105B2 (en) | 1998-03-05 |
DK0557348T3 (da) | 1998-10-07 |
NZ240588A (en) | 1994-12-22 |
ES2114893T3 (es) | 1998-06-16 |
DE69129334D1 (de) | 1998-06-04 |
DE69129334T2 (de) | 1998-08-20 |
AU660429B2 (en) | 1995-06-29 |
EP0557348A1 (en) | 1993-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
N231 | Notification of change of applicant | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application | ||
J201 | Request for trial against refusal decision | ||
J801 | Dismissal of trial |
Free format text: REJECTION OF TRIAL FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 19990802 Effective date: 19991030 Free format text: TRIAL NUMBER: 1999101002823; REJECTION OF TRIAL FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 19990802 Effective date: 19991030 |