KR930010496B1 - 폴리-4-아미노피롤-2-카복스아미도 유도체의 제조방법 - Google Patents
폴리-4-아미노피롤-2-카복스아미도 유도체의 제조방법 Download PDFInfo
- Publication number
- KR930010496B1 KR930010496B1 KR1019860005715A KR860005715A KR930010496B1 KR 930010496 B1 KR930010496 B1 KR 930010496B1 KR 1019860005715 A KR1019860005715 A KR 1019860005715A KR 860005715 A KR860005715 A KR 860005715A KR 930010496 B1 KR930010496 B1 KR 930010496B1
- Authority
- KR
- South Korea
- Prior art keywords
- methyl
- carboxamido
- pyrrole
- compound
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- AWUBEEQAVVDVBL-UHFFFAOYSA-N CC(C=C1)OC1O Chemical compound CC(C=C1)OC1O AWUBEEQAVVDVBL-UHFFFAOYSA-N 0.000 description 1
- 0 C[*@](C(C)=CC(*=CC(C)(C=C)C(C1=CC(N2NCC2(*)C(C2=CC(*)=C*2*)=O)=C*1*)=O)=C**)O Chemical compound C[*@](C(C)=CC(*=CC(C)(C=C)C(C1=CC(N2NCC2(*)C(C2=CC(*)=C*2*)=O)=C*1*)=O)=C**)O 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polyamides (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858517922A GB8517922D0 (en) | 1985-07-16 | 1985-07-16 | Carboxamido derivatives |
| GB8517922 | 1985-07-16 | ||
| GB868613594A GB8613594D0 (en) | 1986-06-04 | 1986-06-04 | Poly-4-aminopyrrole-2-carboxamido derivatives |
| GB8613594 | 1986-06-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR870001201A KR870001201A (ko) | 1987-03-12 |
| KR930010496B1 true KR930010496B1 (ko) | 1993-10-25 |
Family
ID=26289538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019860005715A Expired - Fee Related KR930010496B1 (ko) | 1985-07-16 | 1986-07-15 | 폴리-4-아미노피롤-2-카복스아미도 유도체의 제조방법 |
Country Status (26)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85103908A (zh) * | 1985-07-16 | 1986-11-05 | 法米塔利·卡洛·埃尔巴有限公司 | 制备4′-表多克索红菌素的新方法 |
| GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
| IT1243389B (it) * | 1990-11-22 | 1994-06-10 | Menarini Farma Ind | Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono. |
| CA2103665C (en) * | 1991-02-06 | 2003-04-15 | J. William Lown | Oligopeptide antiretroviral agents |
| IT1247878B (it) * | 1991-02-15 | 1995-01-05 | Menarini Farma Ind | Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono |
| GB2260134A (en) * | 1991-10-04 | 1993-04-07 | Erba Carlo Spa | Derivatives of poly-5-amino-3-carboxy-1-methyl compounds |
| IT1262921B (it) * | 1992-01-10 | 1996-07-22 | Federico Arcamone | Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono |
| GB9416005D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Peptidic compounds analogous to distamycin a and process for their preparation |
| US5717110A (en) * | 1995-09-12 | 1998-02-10 | Kyowa Hakko Kogyo Co., Ltd. | UCH15 compounds |
| EP0880499A1 (en) * | 1996-02-02 | 1998-12-02 | PHARMACIA & UPJOHN S.p.A. | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9615692D0 (en) * | 1996-07-25 | 1996-09-04 | Pharmacia Spa | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB0011059D0 (en) | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
| GB0015446D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
| GB0015447D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
| GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
| US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR86210E (enrdf_load_stackoverflow) * | 1963-04-04 | 1966-03-23 | ||
| BR6461040D0 (pt) * | 1963-07-26 | 1973-08-02 | Farmaceutici Italia | Processo para preparar novos derivados de pirrol |
| DE1795539A1 (de) * | 1963-07-26 | 1972-01-13 | Farmaceutici Italia | Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen |
| BE666612A (enrdf_load_stackoverflow) * | 1963-07-26 | 1965-11-03 | ||
| NL130086C (enrdf_load_stackoverflow) * | 1964-07-14 | 1970-06-15 | ||
| CN85103908A (zh) * | 1985-07-16 | 1986-11-05 | 法米塔利·卡洛·埃尔巴有限公司 | 制备4′-表多克索红菌素的新方法 |
-
1986
- 1986-07-11 AT AT0188886A patent/AT387013B/de not_active IP Right Cessation
- 1986-07-11 SE SE8603098A patent/SE468642B/sv not_active IP Right Cessation
- 1986-07-14 IL IL79402A patent/IL79402A/xx not_active IP Right Cessation
- 1986-07-14 IE IE187586A patent/IE59073B1/en not_active IP Right Cessation
- 1986-07-14 AU AU60202/86A patent/AU587841B2/en not_active Ceased
- 1986-07-14 NL NL8601837A patent/NL8601837A/xx not_active Application Discontinuation
- 1986-07-14 HU HU862904A patent/HU205949B/hu not_active IP Right Cessation
- 1986-07-14 ES ES8600290A patent/ES2000502A6/es not_active Expired
- 1986-07-14 NZ NZ216829A patent/NZ216829A/xx unknown
- 1986-07-15 JP JP61164879A patent/JPH0780843B2/ja not_active Expired - Lifetime
- 1986-07-15 KR KR1019860005715A patent/KR930010496B1/ko not_active Expired - Fee Related
- 1986-07-15 IT IT21125/86A patent/IT1196488B/it active
- 1986-07-15 FR FR868610294A patent/FR2585018B1/fr not_active Expired
- 1986-07-15 DK DK335986A patent/DK335986A/da not_active Application Discontinuation
- 1986-07-15 CA CA000513760A patent/CA1285934C/en not_active Expired - Lifetime
- 1986-07-15 CH CH2820/86A patent/CH674206A5/de not_active IP Right Cessation
- 1986-07-15 BE BE0/216924A patent/BE905110A/fr not_active IP Right Cessation
- 1986-07-15 DE DE3623880A patent/DE3623880A1/de not_active Withdrawn
- 1986-07-15 PH PH34014A patent/PH24714A/en unknown
- 1986-07-15 GR GR861841A patent/GR861841B/el unknown
- 1986-07-15 PT PT82984A patent/PT82984B/pt not_active IP Right Cessation
- 1986-07-15 NO NO862860A patent/NO168826C/no unknown
- 1986-07-16 FI FI862959A patent/FI83640C/fi not_active IP Right Cessation
- 1986-07-16 CN CN86104787A patent/CN1018825B/zh not_active Expired
- 1986-07-16 CS CS865412A patent/CS276981B6/cs unknown
- 1986-07-16 GB GB8617292A patent/GB2178036B/en not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR930010496B1 (ko) | 폴리-4-아미노피롤-2-카복스아미도 유도체의 제조방법 | |
| EP0246868B1 (en) | Site specific alkylating agents | |
| FI90422C (fi) | Menetelmä uusien terapeuttisesti käyttökelpoisten purinyyli- ja pyrimidinyylisyklobutaanijohdannaisten valmistamiseksi | |
| AU635733B2 (en) | Acryloyl substituted pyrrole derivatives | |
| KR940003495B1 (ko) | 디스타마이신 a유도체의 제조방법 | |
| US5049579A (en) | Site specific alkylating agents | |
| US5310752A (en) | Site specific alkylating agents | |
| EP0424899A2 (en) | Novel anthracycline glycoside derivatives and preparing method thereof | |
| US5126347A (en) | Isomeric dideoxynuclesides | |
| KR20000010992A (ko) | 디스타마이신 유도체, 이의 제조 방법, 및 항암 및 항바이러스제제로서의 이들의 용도 | |
| HK1006456B (en) | Acryloyl substituted pyrrole derivatives | |
| HU196590B (en) | Process for producing benzoyl ester derivatives and pharmaceutics comprising them as active ingredient |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| PA0109 | Patent application |
St.27 status event code: A-0-1-A10-A12-nap-PA0109 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
St.27 status event code: A-2-2-Q10-Q13-nap-PG1605 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1 |
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| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
|
| FPAY | Annual fee payment |
Payment date: 19971016 Year of fee payment: 5 |
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| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 5 |
|
| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 19981026 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 19981026 |
|
| P22-X000 | Classification modified |
St.27 status event code: A-4-4-P10-P22-nap-X000 |