KR927003600A - 치료제 - Google Patents
치료제 Download PDFInfo
- Publication number
- KR927003600A KR927003600A KR1019920701870A KR920701870A KR927003600A KR 927003600 A KR927003600 A KR 927003600A KR 1019920701870 A KR1019920701870 A KR 1019920701870A KR 920701870 A KR920701870 A KR 920701870A KR 927003600 A KR927003600 A KR 927003600A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- hydrogen
- formula
- halo
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 claims 13
- 229910052739 hydrogen Inorganic materials 0.000 claims 11
- 239000001257 hydrogen Substances 0.000 claims 11
- 125000003545 alkoxy group Chemical group 0.000 claims 6
- 125000005843 halogen group Chemical group 0.000 claims 6
- 150000002431 hydrogen Chemical class 0.000 claims 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 5
- -1 hydroxy, benzoyl Chemical group 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 3
- 125000001309 chloro group Chemical group Cl* 0.000 claims 3
- 125000004093 cyano group Chemical group *C#N 0.000 claims 3
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 2
- 125000004423 acyloxy group Chemical group 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- WKGKYAZOXFIGPL-UHFFFAOYSA-N 2-(2-ethoxyethyl)-4-[4-(trifluoromethyl)phenyl]chromeno[4,3-c]pyrazol-3-one Chemical compound O=C1N(CCOCC)N=C(C2=CC=CC=C2O2)C1=C2C1=CC=C(C(F)(F)F)C=C1 WKGKYAZOXFIGPL-UHFFFAOYSA-N 0.000 claims 1
- OKFBQNCQZAXIHT-UHFFFAOYSA-N 2-methyl-4-[4-(trifluoromethyl)phenyl]chromeno[4,3-c]pyrazol-3-one Chemical compound O=C1N(C)N=C(C2=CC=CC=C2O2)C1=C2C1=CC=C(C(F)(F)F)C=C1 OKFBQNCQZAXIHT-UHFFFAOYSA-N 0.000 claims 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 1
- 125000004848 alkoxyethyl group Chemical group 0.000 claims 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims 1
- 125000005605 benzo group Chemical group 0.000 claims 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 1
- 125000001589 carboacyl group Chemical group 0.000 claims 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 229940121354 immunomodulator Drugs 0.000 claims 1
- 230000002584 immunomodulator Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9002423.3 | 1990-02-06 | ||
| GB909002423A GB9002423D0 (en) | 1990-02-06 | 1990-02-06 | Therapeutic agents |
| PCT/EP1991/000153 WO1991012255A1 (en) | 1990-02-06 | 1991-01-26 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR927003600A true KR927003600A (ko) | 1992-12-18 |
Family
ID=10670368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920701870A Withdrawn KR927003600A (ko) | 1990-02-06 | 1991-01-26 | 치료제 |
Country Status (16)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9116241D0 (en) * | 1991-07-27 | 1991-09-11 | Boots Co Plc | Therapeutic agents |
| EP1562944B1 (en) | 2002-11-22 | 2007-02-14 | Active Biotech AB | Pyrazoloquinolines with immunomodulating activity |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA895646B (en) * | 1988-08-09 | 1990-04-25 | Boots Co Plc | Therapeutic agents |
-
1990
- 1990-02-06 GB GB909002423A patent/GB9002423D0/en active Pending
-
1991
- 1991-01-24 IN IN51/MAS/91A patent/IN172129B/en unknown
- 1991-01-26 JP JP3503424A patent/JPH05504141A/ja active Pending
- 1991-01-26 WO PCT/EP1991/000153 patent/WO1991012255A1/en active Application Filing
- 1991-01-26 BR BR919105990A patent/BR9105990A/pt unknown
- 1991-01-26 HU HU922540A patent/HUT63848A/hu unknown
- 1991-01-26 CA CA002074816A patent/CA2074816A1/en not_active Abandoned
- 1991-01-26 AU AU71877/91A patent/AU7187791A/en not_active Abandoned
- 1991-01-26 FI FI923528A patent/FI923528A7/fi not_active Application Discontinuation
- 1991-01-26 KR KR1019920701870A patent/KR927003600A/ko not_active Withdrawn
- 1991-01-28 IE IE028791A patent/IE910287A1/en unknown
- 1991-01-31 IL IL97109A patent/IL97109A0/xx unknown
- 1991-02-04 MX MX2440791A patent/MX24407A/es unknown
- 1991-02-05 ZA ZA91833A patent/ZA91833B/xx unknown
- 1991-02-06 PT PT96687A patent/PT96687A/pt unknown
-
1992
- 1992-08-05 NO NO92923082A patent/NO923082L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE910287A1 (en) | 1991-08-14 |
| ZA91833B (en) | 1991-10-30 |
| PT96687A (pt) | 1991-10-31 |
| MX24407A (es) | 1993-10-01 |
| WO1991012255A1 (en) | 1991-08-22 |
| NO923082D0 (no) | 1992-08-05 |
| HUT63848A (en) | 1993-10-28 |
| CA2074816A1 (en) | 1991-08-07 |
| FI923528L (fi) | 1992-08-05 |
| GB9002423D0 (en) | 1990-04-04 |
| FI923528A0 (fi) | 1992-08-05 |
| JPH05504141A (ja) | 1993-07-01 |
| FI923528A7 (fi) | 1992-08-05 |
| BR9105990A (pt) | 1992-11-10 |
| IL97109A0 (en) | 1992-03-29 |
| AU7187791A (en) | 1991-09-03 |
| IN172129B (enrdf_load_stackoverflow) | 1993-04-10 |
| NO923082L (no) | 1992-08-05 |
| HU9202540D0 (en) | 1992-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19920805 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |