KR920016093A - 흡입된 비스테로이드성 소염약제에 의한 흡입된 루프이뇨제의 항반응성-천식치료 효과의 강화 - Google Patents
흡입된 비스테로이드성 소염약제에 의한 흡입된 루프이뇨제의 항반응성-천식치료 효과의 강화 Download PDFInfo
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- KR920016093A KR920016093A KR1019920001736A KR920001736A KR920016093A KR 920016093 A KR920016093 A KR 920016093A KR 1019920001736 A KR1019920001736 A KR 1019920001736A KR 920001736 A KR920001736 A KR 920001736A KR 920016093 A KR920016093 A KR 920016093A
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- inhaled
- nonsteroidal anti
- inflammatory drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
- A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 천식환자 7명의 그룹에 대해 상이한 처리를 한후 증류수의 UNW의 상이한 용량에서의 기본선에 비해 평균 FEV1이 감소하는 것을 도시한 것이다. 제2도는 L-ASA 및 푸로세마이드를 단독으로 및 혼합하여 에어로졸 치료한 후 평균 PD15대 UNW를 도시한 것이다.
Claims (10)
- 천식 치료용 흡입제 제조를 위한 루프 이뇨제와 비스테로이드성 소염약제의 혼합물의 용도.
- 제1항에 있어서, 비스테로이드성 소염약제가 사이클로옥시게나제 억제제인 용도.
- 제1항 또는 제2항에 있어서, 루프 이뇨제가 푸로세마이드인 용도.
- 제1항 또는 제2항에 있어서, 루프 이뇨제가 피레타나이드인 용도.
- 제1항 내지 제4항중 어느 한 항에 있어서, 비스테로이드성 소염약제가 아세틸살리실산인 용도.
- 천식 치료시 흡입에 의해 도포하기 위한 루프 이뇨제 및 비스테로이드성 소염약제의 혼합물.
- 제6항에 있어서, 아세틸살리실산 및 푸로세마이드를 함유하는 혼합물.
- 제6항에 있어서, 인도메타신 및 푸로세마이드를 함유하는 혼합물.
- 제6항에 있어서, 케토프로펜 및 푸로세마이드를 함유하는 혼합물.
- 제6항에 있어서, 테녹시캄 및 푸로세마이드를 함유하는 혼합물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP91101817 | 1991-02-09 | ||
EP91101817.4 | 1991-02-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR920016093A true KR920016093A (ko) | 1992-09-24 |
Family
ID=8206392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019920001736A KR920016093A (ko) | 1991-02-09 | 1992-02-07 | 흡입된 비스테로이드성 소염약제에 의한 흡입된 루프이뇨제의 항반응성-천식치료 효과의 강화 |
Country Status (15)
Country | Link |
---|---|
US (2) | US5366967A (ko) |
EP (1) | EP0499142A3 (ko) |
JP (1) | JPH0680587A (ko) |
KR (1) | KR920016093A (ko) |
AU (1) | AU652798B2 (ko) |
BR (1) | BR9200430A (ko) |
CA (1) | CA2060954A1 (ko) |
CS (1) | CS35392A3 (ko) |
HU (1) | HU209609B (ko) |
IE (1) | IE920426A1 (ko) |
IL (1) | IL100897A0 (ko) |
MX (1) | MX9200570A (ko) |
NO (1) | NO920503L (ko) |
NZ (1) | NZ241541A (ko) |
ZA (1) | ZA92891B (ko) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0499143B1 (en) * | 1991-02-09 | 1999-05-06 | B.S.D. BIO SCIENCE DEVELOPMENT SNC Di OMINI C. & ZUCCARI G. | Anti-reactive anti-asthmatic activity of acetylsalicylic acid by inhalation |
HU219899B (hu) | 1995-04-14 | 2001-09-28 | Glaxo Wellcome Inc. | Inhalálóberendezés flutikaszon-propionát adagolására mért dózisban |
EP1870122A3 (en) | 1995-04-14 | 2008-03-12 | SmithKline Beecham Corporation | Metered dose inhaler |
JP3573213B2 (ja) | 1995-04-14 | 2004-10-06 | グラクソ、ウェルカム、インコーポレーテッド | ベクロメタゾンジプロピオネート用計量投与用吸入器 |
NZ306280A (en) | 1995-04-14 | 1999-07-29 | Glaxo Wellcome Inc | Metered dose inhaler for salmeterol |
DE10034802A1 (de) * | 2000-07-18 | 2002-01-31 | Bayer Ag | Stabile Salze von O-Acetylsalicylsäure mit basischen Aminosäuren |
WO2002092946A1 (en) * | 2001-05-11 | 2002-11-21 | Ray Robert Shorey | Temporary rooftop and stairway safety rail system |
DE10223932A1 (de) * | 2002-05-29 | 2003-12-18 | Rudolf Wank | Verwendung von Diuretika zur Behandlung von Schwellungen |
DE102005025283A1 (de) * | 2005-06-02 | 2006-12-07 | Bayer Healthcare Ag | Stabiler Wirkstoffkomplex von Salzen der o-Acetylsalicylsäure mit basischen Aminosäuren und Glycin |
US9757529B2 (en) * | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
US9757395B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
EP3607941A1 (en) | 2013-04-30 | 2020-02-12 | Otitopic Inc. | Dry powder formulations and methods of use |
PL3107548T3 (pl) | 2014-02-20 | 2022-10-31 | Otitopic Inc. | Suche formulacje w proszku do inhalacji |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4888343A (en) * | 1986-09-15 | 1989-12-19 | Bristol-Myers Company | Pharmaceutical compositions for relief of dysmenorrhea and/or premenstrual syndrome and process |
JPH0720862B2 (ja) * | 1989-01-27 | 1995-03-08 | ヘキスト・アクチエンゲゼルシヤフト | 吸入用喘息治療剤 |
DE3907414A1 (de) * | 1989-03-08 | 1990-09-13 | Hoechst Ag | Die anwendung inhalierter schleifendiuretika zur behandlung von allergen-induzierten nasalen reaktionen |
DE4010536A1 (de) * | 1990-04-02 | 1991-10-10 | Boehringer Mannheim Gmbh | Pharmazeutische waessrige loesung von 4-(2-(benzolsulfonylamino)-ethyl)-phenoxyessigsaeure |
-
1992
- 1992-02-06 EP EP19920101976 patent/EP0499142A3/en not_active Withdrawn
- 1992-02-07 CS CS92353A patent/CS35392A3/cs unknown
- 1992-02-07 AU AU10770/92A patent/AU652798B2/en not_active Ceased
- 1992-02-07 NO NO92920503A patent/NO920503L/no unknown
- 1992-02-07 ZA ZA92891A patent/ZA92891B/xx unknown
- 1992-02-07 KR KR1019920001736A patent/KR920016093A/ko not_active Application Discontinuation
- 1992-02-07 HU HU9200390A patent/HU209609B/hu not_active IP Right Cessation
- 1992-02-07 BR BR929200430A patent/BR9200430A/pt not_active Application Discontinuation
- 1992-02-07 IL IL100897A patent/IL100897A0/xx unknown
- 1992-02-07 JP JP4056157A patent/JPH0680587A/ja active Pending
- 1992-02-07 IE IE042692A patent/IE920426A1/en unknown
- 1992-02-07 NZ NZ241541A patent/NZ241541A/en unknown
- 1992-02-10 CA CA002060954A patent/CA2060954A1/en not_active Abandoned
- 1992-02-10 MX MX9200570A patent/MX9200570A/es unknown
-
1993
- 1993-05-21 US US08/065,450 patent/US5366967A/en not_active Expired - Fee Related
-
1994
- 1994-08-05 US US08/286,445 patent/US5750559A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CS35392A3 (en) | 1992-08-12 |
NO920503L (no) | 1992-08-10 |
JPH0680587A (ja) | 1994-03-22 |
HU9200390D0 (en) | 1992-04-28 |
MX9200570A (es) | 1994-07-29 |
AU1077092A (en) | 1992-08-13 |
US5750559A (en) | 1998-05-12 |
EP0499142A2 (en) | 1992-08-19 |
BR9200430A (pt) | 1992-10-13 |
NZ241541A (en) | 1996-05-28 |
IL100897A0 (en) | 1992-11-15 |
CA2060954A1 (en) | 1992-08-10 |
AU652798B2 (en) | 1994-09-08 |
EP0499142A3 (en) | 1993-05-05 |
US5366967A (en) | 1994-11-22 |
IE920426A1 (en) | 1992-08-12 |
NO920503D0 (no) | 1992-02-07 |
HU209609B (en) | 1994-09-28 |
HUT60438A (en) | 1992-09-28 |
ZA92891B (en) | 1992-12-30 |
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