KR910700048A - 오메프라졸의 항균제로서의 용도 - Google Patents
오메프라졸의 항균제로서의 용도Info
- Publication number
- KR910700048A KR910700048A KR1019900702221A KR900702221A KR910700048A KR 910700048 A KR910700048 A KR 910700048A KR 1019900702221 A KR1019900702221 A KR 1019900702221A KR 900702221 A KR900702221 A KR 900702221A KR 910700048 A KR910700048 A KR 910700048A
- Authority
- KR
- South Korea
- Prior art keywords
- methoxy
- campylobacter
- sulfinyl
- benzimidazole
- pyridinyl
- Prior art date
Links
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 title claims 4
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229960000381 omeprazole Drugs 0.000 title 1
- 241000589876 Campylobacter Species 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 206010051226 Campylobacter infection Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000012678 infectious agent Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (3)
- 캠필로박터(Campylobacter) 박테리아 감염증 치료용 의약품의 제조를 위한 5-메톡시-2-〔〔(4-메톡시-3,5-디메틸-2-피리디닐)메틸〕술피닐〕-1H-벤즈이미다졸 또는 그의 제약상 허용되는 염의 용도.
- 캠필로박터 감염증 환자에게 5-메톡시-2-〔〔(4-메톡시-3,5-디메틸-2-피리디닐)메틸〕술피닐〕-1H-벤즈이미다졸 또는 그의 제약상 허용되는 염을 캠필로박터 감염증 치료에 충분한 양으로 투여하는 것으로 이루어진 캠필로박터 감염증 치료 방법.
- 활성 성분이 5-메톡시-2-〔〔(4-메톡시-3,5-디메틸-2-피리디닐)메틸〕술피닐〕-1H-벤즈이미다졸 또는 그의 제약상 허용되는 염인 캠필로박터 감염증 치료용 약제.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1/30311 | 1989-02-09 | ||
JP1030311A JP2694361B2 (ja) | 1989-02-09 | 1989-02-09 | 抗菌剤 |
PCT/SE1990/000070 WO1990009175A1 (en) | 1989-02-09 | 1990-02-02 | Use of omeprazole as an antimicrobial agent |
Publications (2)
Publication Number | Publication Date |
---|---|
KR910700048A true KR910700048A (ko) | 1991-03-13 |
KR0140236B1 KR0140236B1 (ko) | 1998-06-01 |
Family
ID=12300238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019900702221A KR0140236B1 (ko) | 1989-02-09 | 1990-02-02 | 오메프라졸의 항균제로서의 용도 |
Country Status (19)
Country | Link |
---|---|
US (1) | US5093342A (ko) |
EP (1) | EP0414847B1 (ko) |
JP (1) | JP2694361B2 (ko) |
KR (1) | KR0140236B1 (ko) |
AT (1) | ATE94063T1 (ko) |
AU (1) | AU626641B2 (ko) |
CA (1) | CA2025668C (ko) |
CY (1) | CY1909A (ko) |
DE (1) | DE69003207T2 (ko) |
DK (1) | DK0414847T3 (ko) |
ES (1) | ES2058892T3 (ko) |
HK (1) | HK52196A (ko) |
HU (1) | HU205253B (ko) |
IE (1) | IE65814B1 (ko) |
IL (1) | IL93263A0 (ko) |
LV (1) | LV10577B (ko) |
MY (1) | MY111737A (ko) |
PH (1) | PH26787A (ko) |
WO (1) | WO1990009175A1 (ko) |
Families Citing this family (60)
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ES2066120T3 (es) * | 1989-02-10 | 1995-03-01 | Takeda Chemical Industries Ltd | Uso de derivados de bencimidazol como agentes antibacterianos. |
GB9018603D0 (en) * | 1990-08-24 | 1990-10-10 | Smith Kline French Lab | Compositions |
WO1992004898A1 (de) * | 1990-09-14 | 1992-04-02 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Verwendung von pyridylmethylsulfinyl-1h-benzimidazol derivaten zur behandlung durch helicobacter verursachten erkrankungen |
IL105155A (en) * | 1992-04-24 | 1999-05-09 | Astra Ab | Synergistic combination of an inhibitor of gastric acid secretion with an acid-breaking antibiotic |
US5504082A (en) * | 1992-06-01 | 1996-04-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridine compound and pharmaceutical compostions |
AU5699594A (en) * | 1992-12-10 | 1994-07-04 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Use of alkylthiopyridines for controlling helicobacter bacteria |
US6902738B2 (en) * | 1994-05-02 | 2005-06-07 | Josman Laboratories, Inc. | Topical oral dosage forms containing bismuth compounds |
US6426085B1 (en) | 1994-05-02 | 2002-07-30 | Josman Laboratories Inc. | Use of bismuth-containing compounds in topical oral dosage forms for the treatment of halitosis |
US5834002A (en) | 1994-05-02 | 1998-11-10 | Josman Laboratories, Inc. | Chewing gum containing colloidal bismuth subcitrate |
AU4596796A (en) * | 1995-02-07 | 1996-08-27 | Narayan Krishnarao Athanikar | Concomitant treatment with bismuth and antibacterials |
US6379651B1 (en) | 1995-02-07 | 2002-04-30 | Josman Laboratories | Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases |
US6372784B1 (en) | 1995-02-07 | 2002-04-16 | Josman Laboratories, Inc. | Bismuth-containing compounds in topical dosage forms for treatment of corneal and dermal wounds |
US5708017A (en) * | 1995-04-04 | 1998-01-13 | Merck & Co., Inc. | Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors |
US6645988B2 (en) * | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
SI9700186B (sl) | 1997-07-14 | 2006-10-31 | Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. | Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin |
US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
ATE260090T1 (de) * | 1997-12-08 | 2004-03-15 | Altana Pharma Ag | Neue suppositoriumsform mit säureempfindliche wirkstoffe |
US6861448B2 (en) * | 1998-01-14 | 2005-03-01 | Virtual Drug Development, Inc. | NAD synthetase inhibitors and uses thereof |
WO1999036422A1 (en) | 1998-01-14 | 1999-07-22 | The Uab Research Foundation | Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial nad synthetase enzyme |
US6733778B1 (en) * | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
US6787342B2 (en) | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
SE0002476D0 (sv) | 2000-06-30 | 2000-06-30 | Astrazeneca Ab | New compounds |
EP2147679B1 (en) | 2001-07-25 | 2014-06-25 | Raptor Pharmaceutical, Inc. | Compositions for blood-brain barrier transport |
EP1469839A2 (en) * | 2002-01-25 | 2004-10-27 | Santarus, Inc. | Transmucosal delivery of proton pump inhibitors |
JP2006518751A (ja) * | 2003-02-20 | 2006-08-17 | サンタラス インコーポレイティッド | 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物 |
TWI337877B (en) * | 2003-07-18 | 2011-03-01 | Santarus Inc | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
CA2531564C (en) * | 2003-07-18 | 2016-01-19 | Santarus, Inc. | Pharmaceutical composition for inhibiting acid secretion |
US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
WO2006116718A2 (en) | 2005-04-28 | 2006-11-02 | Proteus Biomedical, Inc. | Pharma-informatics system |
KR101348643B1 (ko) | 2006-03-10 | 2014-01-08 | 링크 제노믹스 가부시키가이샤 | 항 헬리코박터피로리 작용을 가지는 신규 피리딘 유도체 |
EP2068841B1 (en) | 2006-10-05 | 2018-09-26 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
EP2486910A3 (en) | 2006-10-27 | 2012-08-22 | The Curators Of The University Of Missouri | Multi-chambered apparatus comprising a dispenser head |
PL2103608T3 (pl) | 2006-12-18 | 2013-02-28 | Link Genomics Inc | Środek do eradykacji Helicobacter pylori mający działanie hamujące na sekrecję kwasu żołądkowego |
US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
JP5564517B2 (ja) | 2009-02-20 | 2014-07-30 | ティーオー − ビービービー ホールディング ベスローテン フェンノートシャップ | グルタチオンをベースとする薬物送達システム |
WO2010116740A1 (ja) | 2009-04-09 | 2010-10-14 | アリジェン製薬株式会社 | ピリジンチオ誘導体及びそれを含有する抗ヘリコバクター・ピロリ作用を有する医薬組成物 |
CN102458374A (zh) | 2009-05-06 | 2012-05-16 | 实验室护肤股份有限公司 | 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法 |
US8992897B2 (en) | 2010-01-06 | 2015-03-31 | Elc Management Llc | Skin lightening compositions |
US8722026B2 (en) * | 2010-01-06 | 2014-05-13 | Elc Management, Llc | Skin lightening compositions |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
KR101628474B1 (ko) * | 2014-08-27 | 2016-06-08 | 경북대학교 산학협력단 | 오메프라졸을 유효성분으로 포함하는 피부 미백용 화장료 조성물 |
WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
HU886738D0 (en) * | 1987-10-30 | 1990-02-28 | Haessle Ab | Process for the preparation of pharmaceutical compositions against osteoporosis containing 2-pyridinyl-methyl-(sulfinyl or thio)-benzimidazoles |
-
1989
- 1989-02-09 JP JP1030311A patent/JP2694361B2/ja not_active Expired - Lifetime
-
1990
- 1990-02-02 ES ES90902854T patent/ES2058892T3/es not_active Expired - Lifetime
- 1990-02-02 CA CA002025668A patent/CA2025668C/en not_active Expired - Lifetime
- 1990-02-02 KR KR1019900702221A patent/KR0140236B1/ko not_active IP Right Cessation
- 1990-02-02 AU AU50381/90A patent/AU626641B2/en not_active Ceased
- 1990-02-02 DE DE90902854T patent/DE69003207T2/de not_active Expired - Fee Related
- 1990-02-02 HU HU901539A patent/HU205253B/hu not_active IP Right Cessation
- 1990-02-02 US US07/572,951 patent/US5093342A/en not_active Expired - Fee Related
- 1990-02-02 CY CY190990A patent/CY1909A/xx unknown
- 1990-02-02 WO PCT/SE1990/000070 patent/WO1990009175A1/en active IP Right Grant
- 1990-02-02 EP EP90902854A patent/EP0414847B1/en not_active Expired - Lifetime
- 1990-02-02 AT AT90902854T patent/ATE94063T1/de not_active IP Right Cessation
- 1990-02-02 DK DK90902854.0T patent/DK0414847T3/da active
- 1990-02-02 IL IL93263A patent/IL93263A0/xx not_active IP Right Cessation
- 1990-02-06 IE IE41890A patent/IE65814B1/en not_active IP Right Cessation
- 1990-02-09 PH PH40033A patent/PH26787A/en unknown
- 1990-02-09 MY MYPI90000213A patent/MY111737A/en unknown
-
1994
- 1994-08-30 LV LVP-94-169A patent/LV10577B/en unknown
-
1996
- 1996-03-21 HK HK52196A patent/HK52196A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0414847B1 (en) | 1993-09-08 |
US5093342A (en) | 1992-03-03 |
MY111737A (en) | 2000-12-30 |
AU626641B2 (en) | 1992-08-06 |
KR0140236B1 (ko) | 1998-06-01 |
CY1909A (en) | 1990-02-02 |
AU5038190A (en) | 1990-09-05 |
LV10577A (lv) | 1995-04-20 |
DE69003207D1 (de) | 1993-10-14 |
EP0414847A1 (en) | 1991-03-06 |
HK52196A (en) | 1996-03-29 |
PH26787A (en) | 1992-10-13 |
IE65814B1 (en) | 1995-11-15 |
ATE94063T1 (de) | 1993-09-15 |
WO1990009175A1 (en) | 1990-08-23 |
CA2025668A1 (en) | 1990-08-10 |
IL93263A0 (en) | 1990-11-29 |
ES2058892T3 (es) | 1994-11-01 |
IE900418L (en) | 1990-08-09 |
HU901539D0 (en) | 1991-02-28 |
LV10577B (en) | 1995-10-20 |
HUT54890A (en) | 1991-04-29 |
CA2025668C (en) | 1998-09-15 |
DE69003207T2 (de) | 1994-02-03 |
JPH02209809A (ja) | 1990-08-21 |
HU205253B (en) | 1992-04-28 |
DK0414847T3 (da) | 1993-12-13 |
JP2694361B2 (ja) | 1997-12-24 |
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Legal Events
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A201 | Request for examination | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20080117 Year of fee payment: 11 |
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LAPS | Lapse due to unpaid annual fee |