KR910009260A - 퀴놀릴- 및 이소퀴놀릴옥사졸- 2- 온의 당단백질 외막 바이러스 감염 치료 용도 - Google Patents

퀴놀릴- 및 이소퀴놀릴옥사졸- 2- 온의 당단백질 외막 바이러스 감염 치료 용도 Download PDF

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KR910009260A
KR910009260A KR1019900018247A KR900018247A KR910009260A KR 910009260 A KR910009260 A KR 910009260A KR 1019900018247 A KR1019900018247 A KR 1019900018247A KR 900018247 A KR900018247 A KR 900018247A KR 910009260 A KR910009260 A KR 910009260A
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South Korea
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group
quinolyl
alkyl
treatment
virus infection
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KR1019900018247A
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KR0162639B1 (ko
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프래서드 선카라 사이
데니스 존스 윈톤
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게리 디.스트리트
메렐 다우 파마슈티칼스 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

내용 없음

Description

퀴놀릴- 및 이소퀴놀옥사졸-2-온의 당단백질 외막 바이러스 감염 치료 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 하기 일반식(I)의 화합물 또는 그의 제약상 허용되는 염의 외막 바이러스 감염 치료제로서의 용도.
    상기식에서, R및 R1은 각각 독립적으로 수소, C1-C6알킬 및 페닐 또는 C1-C3알킬페닐기(여기서, 페닐 고리는 불소, 염소, 브롬, C1-C4알킬 및 C1-C4알콕시기로 구성된 군 중에서 선택된 1,2 또는 3개의 치환기로 치환될 수 있음)로 구성된 군중에서 선택되며, R2는 불소, 염소, 브롬, C1-C4알킬, C1-C4알콕시, 니트로, 트리플루오로 메틸 및 페닐기(이 페닐기는 불소, 염소, 브롬, C1-C4알킬 및 C1-C4알콕시로 구성된 군 중에서 선택된 1,2 또는 3개의 치환기로 치환될 수 있음)로 구성된 군중에서 선택된 1,2 또는 3개의 치환기로 치환될 수 있는 2-, 3-또는 4-퀴놀릴기 또는 1-, 3-또는 4-이소퀴놀릴기이거나, 또는 R2는 5-, 6-,7- 또는 퀴놀릴 또는 이소퀴놀릴기이다.
  2. 제1항에 있어서, 외막 바이러스가 HIV인 것을 특징으로 하는 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900018247A 1989-11-13 1990-11-12 퀴놀릴-및 이소퀴놀릴옥사졸-2-온의 당단백질 외막 바이러스 감염 치료 용도 KR0162639B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43531889A 1989-11-13 1989-11-13
US435318 1989-11-13
US435,318 1989-11-13

Publications (2)

Publication Number Publication Date
KR910009260A true KR910009260A (ko) 1991-06-28
KR0162639B1 KR0162639B1 (ko) 1998-12-01

Family

ID=23727911

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900018247A KR0162639B1 (ko) 1989-11-13 1990-11-12 퀴놀릴-및 이소퀴놀릴옥사졸-2-온의 당단백질 외막 바이러스 감염 치료 용도

Country Status (11)

Country Link
EP (1) EP0428105B1 (ko)
JP (1) JP2927930B2 (ko)
KR (1) KR0162639B1 (ko)
AT (1) ATE100318T1 (ko)
AU (1) AU630249B2 (ko)
DE (1) DE69006187T2 (ko)
DK (1) DK0428105T3 (ko)
ES (1) ES2062266T3 (ko)
IE (1) IE63851B1 (ko)
PH (1) PH27309A (ko)
ZA (1) ZA908933B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107327A (en) * 1996-08-30 2000-08-22 Eli Lilly And Company Therapeutic treatment for HIV infection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886811A (en) * 1988-10-24 1989-12-12 Merrell Dow Pharmaceuticals Qunolyloxazole-2-ones useful as proteinkinase C inhibitors

Also Published As

Publication number Publication date
IE904079A1 (en) 1991-05-22
AU6592990A (en) 1991-05-16
ZA908933B (en) 1991-08-28
DE69006187D1 (de) 1994-03-03
IE63851B1 (en) 1995-06-14
JP2927930B2 (ja) 1999-07-28
KR0162639B1 (ko) 1998-12-01
DE69006187T2 (de) 1994-05-05
EP0428105B1 (en) 1994-01-19
AU630249B2 (en) 1992-10-22
JPH03173886A (ja) 1991-07-29
EP0428105A2 (en) 1991-05-22
EP0428105A3 (en) 1991-12-11
ATE100318T1 (de) 1994-02-15
PH27309A (en) 1993-05-28
DK0428105T3 (da) 1994-02-28
ES2062266T3 (es) 1994-12-16

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