KR910006763B1 - N-니트로소 화합물 및 이의 제조방법 - Google Patents
N-니트로소 화합물 및 이의 제조방법 Download PDFInfo
- Publication number
- KR910006763B1 KR910006763B1 KR1019830004238A KR830004238A KR910006763B1 KR 910006763 B1 KR910006763 B1 KR 910006763B1 KR 1019830004238 A KR1019830004238 A KR 1019830004238A KR 830004238 A KR830004238 A KR 830004238A KR 910006763 B1 KR910006763 B1 KR 910006763B1
- Authority
- KR
- South Korea
- Prior art keywords
- chloroethyl
- ethyl
- nitrosourea
- formula
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 0 B*(*S(*(*)*)=O)C(N(*)*)=O Chemical compound B*(*S(*(*)*)=O)C(N(*)*)=O 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/47—Y being a hetero atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Optical Head (AREA)
- Reverberation, Karaoke And Other Acoustics (AREA)
- Gyroscopes (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8205324A SE8205324L (sv) | 1982-09-17 | 1982-09-17 | Nya n-nitrosoforeningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder |
| SE8205324-0 | 1982-09-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR840006330A KR840006330A (ko) | 1984-11-29 |
| KR910006763B1 true KR910006763B1 (ko) | 1991-09-02 |
Family
ID=20347890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019830004238A Expired KR910006763B1 (ko) | 1982-09-17 | 1983-09-08 | N-니트로소 화합물 및 이의 제조방법 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4613695A (https=) |
| EP (1) | EP0106123B1 (https=) |
| JP (1) | JPS5973562A (https=) |
| KR (1) | KR910006763B1 (https=) |
| AT (1) | ATE17235T1 (https=) |
| AU (1) | AU559738B2 (https=) |
| CA (1) | CA1242200A (https=) |
| DE (1) | DE3361719D1 (https=) |
| DK (1) | DK423983A (https=) |
| ES (1) | ES525662A0 (https=) |
| FI (1) | FI76553C (https=) |
| GR (1) | GR79656B (https=) |
| HK (1) | HK35389A (https=) |
| HU (1) | HU194817B (https=) |
| IE (1) | IE55901B1 (https=) |
| IL (1) | IL69660A0 (https=) |
| NO (1) | NO159084C (https=) |
| NZ (1) | NZ205534A (https=) |
| PH (1) | PH21576A (https=) |
| PT (1) | PT77349B (https=) |
| SE (1) | SE8205324L (https=) |
| SG (1) | SG789G (https=) |
| ZA (1) | ZA836569B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5001158A (en) * | 1984-04-11 | 1991-03-19 | Centre National De La Recherche Scientifique | Nitrosoureas compounds preparation thereof and utilization thereof in anticancerous |
| WO2001098268A2 (en) * | 2000-06-21 | 2001-12-27 | Bristol-Myers Squibb Pharma Company | Piperidine amides as modulators of chemokine receptor activity |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE50228B1 (en) * | 1979-10-03 | 1986-03-05 | Kefalas As | Nitrosourea derivatives,process for preparing them,and pharmaceutical compositions containing them |
-
1982
- 1982-09-17 SE SE8205324A patent/SE8205324L/xx not_active Application Discontinuation
-
1983
- 1983-08-26 IE IE2006/83A patent/IE55901B1/en not_active IP Right Cessation
- 1983-09-05 AU AU18707/83A patent/AU559738B2/en not_active Ceased
- 1983-09-05 IL IL69660A patent/IL69660A0/xx not_active IP Right Cessation
- 1983-09-05 ZA ZA836569A patent/ZA836569B/xx unknown
- 1983-09-06 US US06/529,718 patent/US4613695A/en not_active Expired - Fee Related
- 1983-09-08 KR KR1019830004238A patent/KR910006763B1/ko not_active Expired
- 1983-09-08 DE DE8383108853T patent/DE3361719D1/de not_active Expired
- 1983-09-08 AT AT83108853T patent/ATE17235T1/de not_active IP Right Cessation
- 1983-09-08 EP EP83108853A patent/EP0106123B1/en not_active Expired
- 1983-09-09 NZ NZ205534A patent/NZ205534A/en unknown
- 1983-09-13 FI FI833266A patent/FI76553C/fi not_active IP Right Cessation
- 1983-09-15 PH PH29543A patent/PH21576A/en unknown
- 1983-09-15 GR GR72451A patent/GR79656B/el unknown
- 1983-09-16 DK DK423983A patent/DK423983A/da not_active Application Discontinuation
- 1983-09-16 NO NO833354A patent/NO159084C/no unknown
- 1983-09-16 HU HU833220A patent/HU194817B/hu not_active IP Right Cessation
- 1983-09-16 ES ES525662A patent/ES525662A0/es active Granted
- 1983-09-16 CA CA000436928A patent/CA1242200A/en not_active Expired
- 1983-09-16 PT PT77349A patent/PT77349B/pt not_active IP Right Cessation
- 1983-09-16 JP JP58171054A patent/JPS5973562A/ja active Granted
-
1989
- 1989-01-05 SG SG7/89A patent/SG789G/en unknown
- 1989-04-27 HK HK353/89A patent/HK35389A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR840006330A (ko) | 1984-11-29 |
| IE832006L (en) | 1984-03-17 |
| DK423983D0 (da) | 1983-09-16 |
| FI76553B (fi) | 1988-07-29 |
| EP0106123B1 (en) | 1986-01-02 |
| HK35389A (en) | 1989-05-05 |
| ZA836569B (en) | 1984-04-25 |
| AU559738B2 (en) | 1987-03-19 |
| SE8205324D0 (sv) | 1982-09-17 |
| SE8205324L (sv) | 1984-03-18 |
| PT77349B (en) | 1986-04-17 |
| FI76553C (fi) | 1988-11-10 |
| PH21576A (en) | 1987-12-11 |
| AU1870783A (en) | 1984-03-22 |
| JPH0333152B2 (https=) | 1991-05-16 |
| HU194817B (en) | 1988-03-28 |
| FI833266A7 (fi) | 1984-03-18 |
| ES8405367A1 (es) | 1984-06-01 |
| CA1242200A (en) | 1988-09-20 |
| GR79656B (https=) | 1984-10-31 |
| FI833266A0 (fi) | 1983-09-13 |
| NO159084C (no) | 1988-11-30 |
| JPS5973562A (ja) | 1984-04-25 |
| DK423983A (da) | 1984-03-18 |
| ES525662A0 (es) | 1984-06-01 |
| PT77349A (en) | 1983-10-01 |
| NO159084B (no) | 1988-08-22 |
| NZ205534A (en) | 1986-10-08 |
| DE3361719D1 (en) | 1986-02-13 |
| NO833354L (no) | 1984-03-19 |
| SG789G (en) | 1989-07-14 |
| EP0106123A1 (en) | 1984-04-25 |
| ATE17235T1 (de) | 1986-01-15 |
| US4613695A (en) | 1986-09-23 |
| IE55901B1 (en) | 1991-02-14 |
| IL69660A0 (en) | 1983-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2901701T3 (es) | Método para preparar intermedio de derivado de 4-metoxipirrol | |
| US20230174583A1 (en) | Preparation of cyclosporin derivatives | |
| US4150146A (en) | Process for the preparation of unsymmetrically 1,3-disubstituted nitroso ureas | |
| KR910006763B1 (ko) | N-니트로소 화합물 및 이의 제조방법 | |
| EP0146838B1 (en) | (alkylsulfonyl)methanesulfonates as anticancer agents | |
| EP0192242B1 (en) | Substituted aminophenylurea derivatives | |
| US4727174A (en) | (Alkylsulfonyl)methanesulfonates as anticancer agents | |
| US4452814A (en) | Nitrosourea derivatives | |
| MORIKAWA et al. | A new class of nitrosoureas. III. Synthesis and antitumor activity of 3, 3-disubstituted-1-(2-chloroethyl)-1-nitrosoureas having an arabinopyranosyl, xylopyranosyl or ribopyranosyl moiety | |
| Scully Jr et al. | Formation of thiocarbamates in the oxidative condensation of amines and organic N-chloroamines with potassium ethyl xanthate | |
| Avdeenko et al. | Activated sterically strained C= N bond in N-arylsulfonyl-p-quinonemono-and diimines: IX. Synthesis and reactions of N-tosyl-2, 3, 5, 6-tetramethyl-1, 4-benzoquinonimine | |
| US3226379A (en) | Novel 1,3-bis(polyhydroxyalkyl)-2-imidazolidinones and 1,3-bis(polyhydroxyalkyl)-imidazolidine-2-thiones | |
| EP3986905A1 (en) | Large scale process of 3,3'-dideoxy-3,3'-bis-[4-(3-fluorophenyl)-1h-1,2,3-triazol-1-yl]-1,1'-sulfanediyl-di-beta-d-galactopyranoside | |
| US4218396A (en) | Phenylene-bis (substituted thioureas) | |
| JPH082865B2 (ja) | 抗潰瘍作用を有する化合物の製法 | |
| Chen et al. | The Synthesis of Novel Derivatives of 1, 5-Dihydro-4-Mercapto-2, 6-Dioxo-1, 3, 5, 2-Triazaphosphorine and Their Antitumor Activity | |
| US3074850A (en) | Analgesic, antipyretic n-methyl-n'-halophenyl-urea | |
| US4251515A (en) | Novel nitrosourea derivatives | |
| US5463075A (en) | Process for preparing 1,2-pyrazolidine-4-yl-disulfide compound | |
| EP0080609B1 (en) | Novel compound having analgesic, antiinflammatory and antipyretic activity, process for its preparation and pharmaceutical compositions containing it | |
| Cheung et al. | Multi‐13 C‐labelled inhibitors of tubulin assembly: 5‐substituted methyl N‐(1H‐benzimidazol‐2‐YL) carbamates | |
| Gallant et al. | Synthesis, chemical half-life and decomposition of new N3-(substituted) derivatives of CCNU | |
| BR112019027323B1 (pt) | Método para preparar intermediário de derivado de 4-metoxipirrol | |
| JPS63280054A (ja) | 活性化ニトロソカルバメートの製造方法 | |
| JPS639513B2 (https=) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
St.27 status event code: A-0-1-A10-A12-nap-PA0109 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
St.27 status event code: A-2-2-Q10-Q13-nap-PG1605 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1 |
|
| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 19940903 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 19940903 |
|
| P22-X000 | Classification modified |
St.27 status event code: A-4-4-P10-P22-nap-X000 |