DE3361719D1 - Novel n-nitroso compounds, compositions containing such compounds and processes for their preparation - Google Patents
Novel n-nitroso compounds, compositions containing such compounds and processes for their preparationInfo
- Publication number
- DE3361719D1 DE3361719D1 DE8383108853T DE3361719T DE3361719D1 DE 3361719 D1 DE3361719 D1 DE 3361719D1 DE 8383108853 T DE8383108853 T DE 8383108853T DE 3361719 T DE3361719 T DE 3361719T DE 3361719 D1 DE3361719 D1 DE 3361719D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- alkylene
- alkyl
- so2nr3r4
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000004008 N-nitroso compounds Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000002947 alkylene group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/47—Y being a hetero atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Optical Head (AREA)
- Reverberation, Karaoke And Other Acoustics (AREA)
- Gyroscopes (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8205324A SE8205324L (sv) | 1982-09-17 | 1982-09-17 | Nya n-nitrosoforeningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3361719D1 true DE3361719D1 (en) | 1986-02-13 |
Family
ID=20347890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8383108853T Expired DE3361719D1 (en) | 1982-09-17 | 1983-09-08 | Novel n-nitroso compounds, compositions containing such compounds and processes for their preparation |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4613695A (https=) |
| EP (1) | EP0106123B1 (https=) |
| JP (1) | JPS5973562A (https=) |
| KR (1) | KR910006763B1 (https=) |
| AT (1) | ATE17235T1 (https=) |
| AU (1) | AU559738B2 (https=) |
| CA (1) | CA1242200A (https=) |
| DE (1) | DE3361719D1 (https=) |
| DK (1) | DK423983A (https=) |
| ES (1) | ES525662A0 (https=) |
| FI (1) | FI76553C (https=) |
| GR (1) | GR79656B (https=) |
| HK (1) | HK35389A (https=) |
| HU (1) | HU194817B (https=) |
| IE (1) | IE55901B1 (https=) |
| IL (1) | IL69660A0 (https=) |
| NO (1) | NO159084C (https=) |
| NZ (1) | NZ205534A (https=) |
| PH (1) | PH21576A (https=) |
| PT (1) | PT77349B (https=) |
| SE (1) | SE8205324L (https=) |
| SG (1) | SG789G (https=) |
| ZA (1) | ZA836569B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5001158A (en) * | 1984-04-11 | 1991-03-19 | Centre National De La Recherche Scientifique | Nitrosoureas compounds preparation thereof and utilization thereof in anticancerous |
| WO2001098268A2 (en) * | 2000-06-21 | 2001-12-27 | Bristol-Myers Squibb Pharma Company | Piperidine amides as modulators of chemokine receptor activity |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE50228B1 (en) * | 1979-10-03 | 1986-03-05 | Kefalas As | Nitrosourea derivatives,process for preparing them,and pharmaceutical compositions containing them |
-
1982
- 1982-09-17 SE SE8205324A patent/SE8205324L/xx not_active Application Discontinuation
-
1983
- 1983-08-26 IE IE2006/83A patent/IE55901B1/en not_active IP Right Cessation
- 1983-09-05 AU AU18707/83A patent/AU559738B2/en not_active Ceased
- 1983-09-05 IL IL69660A patent/IL69660A0/xx not_active IP Right Cessation
- 1983-09-05 ZA ZA836569A patent/ZA836569B/xx unknown
- 1983-09-06 US US06/529,718 patent/US4613695A/en not_active Expired - Fee Related
- 1983-09-08 KR KR1019830004238A patent/KR910006763B1/ko not_active Expired
- 1983-09-08 DE DE8383108853T patent/DE3361719D1/de not_active Expired
- 1983-09-08 AT AT83108853T patent/ATE17235T1/de not_active IP Right Cessation
- 1983-09-08 EP EP83108853A patent/EP0106123B1/en not_active Expired
- 1983-09-09 NZ NZ205534A patent/NZ205534A/en unknown
- 1983-09-13 FI FI833266A patent/FI76553C/fi not_active IP Right Cessation
- 1983-09-15 PH PH29543A patent/PH21576A/en unknown
- 1983-09-15 GR GR72451A patent/GR79656B/el unknown
- 1983-09-16 DK DK423983A patent/DK423983A/da not_active Application Discontinuation
- 1983-09-16 NO NO833354A patent/NO159084C/no unknown
- 1983-09-16 HU HU833220A patent/HU194817B/hu not_active IP Right Cessation
- 1983-09-16 ES ES525662A patent/ES525662A0/es active Granted
- 1983-09-16 CA CA000436928A patent/CA1242200A/en not_active Expired
- 1983-09-16 PT PT77349A patent/PT77349B/pt not_active IP Right Cessation
- 1983-09-16 JP JP58171054A patent/JPS5973562A/ja active Granted
-
1989
- 1989-01-05 SG SG7/89A patent/SG789G/en unknown
- 1989-04-27 HK HK353/89A patent/HK35389A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR840006330A (ko) | 1984-11-29 |
| IE832006L (en) | 1984-03-17 |
| DK423983D0 (da) | 1983-09-16 |
| FI76553B (fi) | 1988-07-29 |
| EP0106123B1 (en) | 1986-01-02 |
| HK35389A (en) | 1989-05-05 |
| ZA836569B (en) | 1984-04-25 |
| AU559738B2 (en) | 1987-03-19 |
| SE8205324D0 (sv) | 1982-09-17 |
| SE8205324L (sv) | 1984-03-18 |
| PT77349B (en) | 1986-04-17 |
| FI76553C (fi) | 1988-11-10 |
| PH21576A (en) | 1987-12-11 |
| AU1870783A (en) | 1984-03-22 |
| JPH0333152B2 (https=) | 1991-05-16 |
| HU194817B (en) | 1988-03-28 |
| FI833266A7 (fi) | 1984-03-18 |
| ES8405367A1 (es) | 1984-06-01 |
| KR910006763B1 (ko) | 1991-09-02 |
| CA1242200A (en) | 1988-09-20 |
| GR79656B (https=) | 1984-10-31 |
| FI833266A0 (fi) | 1983-09-13 |
| NO159084C (no) | 1988-11-30 |
| JPS5973562A (ja) | 1984-04-25 |
| DK423983A (da) | 1984-03-18 |
| ES525662A0 (es) | 1984-06-01 |
| PT77349A (en) | 1983-10-01 |
| NO159084B (no) | 1988-08-22 |
| NZ205534A (en) | 1986-10-08 |
| NO833354L (no) | 1984-03-19 |
| SG789G (en) | 1989-07-14 |
| EP0106123A1 (en) | 1984-04-25 |
| ATE17235T1 (de) | 1986-01-15 |
| US4613695A (en) | 1986-09-23 |
| IE55901B1 (en) | 1991-02-14 |
| IL69660A0 (en) | 1983-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Free format text: DERZEIT KEIN VERTRETER BESTELLT |
|
| 8339 | Ceased/non-payment of the annual fee |