KR910000140A - 신장 질환 치료용 영양제제 - Google Patents

신장 질환 치료용 영양제제 Download PDF

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Publication number
KR910000140A
KR910000140A KR1019900009129A KR900009129A KR910000140A KR 910000140 A KR910000140 A KR 910000140A KR 1019900009129 A KR1019900009129 A KR 1019900009129A KR 900009129 A KR900009129 A KR 900009129A KR 910000140 A KR910000140 A KR 910000140A
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South Korea
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composition
ketoisocaproate
keto
suspended
dissolved
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KR1019900009129A
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English (en)
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앤 앤더슨 파멜라
시폴로 켄트리
가보 모학시 티바다
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챨스 엠.브록
애보트 라보라토리즈
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23454347&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR910000140(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 챨스 엠.브록, 애보트 라보라토리즈 filed Critical 챨스 엠.브록
Publication of KR910000140A publication Critical patent/KR910000140A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Non-Alcoholic Beverages (AREA)

Abstract

내용 없음

Description

신장 질환 치료용 영양제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (12)

  1. 신부전증으로 고생하는 환자에게 유효 영양 용량의 하기 성분을 하기 중량%로 포함하는 조성물을 장내 또는 비경구 투여함을 특징으로 하여 신부전증으로 고생하는 환자를 양양 치료하는 방법.
    L-오르니틴-α-케토이소발레레이트 20 내지 25%L-오르니틴-α=케토이소캐프로에이트 20 내지 25%L-리신-α-케토-β메틸발레레이트 20 내지 25%L-히스티딘-α-케토이소캐프로에이트 5 내지 9% α-하이드록시-γ-메틸티로부티레이트의 칼슘염, 나트륨염 또는 칼륨염 1 내지 3%L-트립토판 0.1 내지 1%L-티로신 15 내지 20%L-트레오닌 3 내지 7%.
  2. 제1항에 있어서, 조성물을 저단백식이와 함께 투여하는 방법.
  3. 제1항에 있어서, 조성물을 투여하기 전에 수성 매질에 용해/현탁시키는 방법.
  4. 제1항에 있어서, 조성물을 투여하기 전에 향미제를 함유하는 수성 매질에 용해/현탁 시키는 방법.
  5. 제1항에 있어서, 조성물을 투여하기 전에 과일 쥬스에 용해/현탁시키는 방법.
  6. 신부전증으로 고생하는 환자에게 유효 영양 용량의 하기 성분을 하기 중량%로 포함하는 조성물을 장내 또는 비경구 투여함을 특징으로 하여 신부전증으로 고생하는 환자를 영양 치료하는 방법.
    L-오르티닌-α-케토이소발레레이트 20 내지 25%L-오르니틴-α-케토-메틸발레레이트 20 내지 25%L-리신-α-케토-케토이소캐프로에이트 20 내지 25%L-히스티딘-α-케토이소캐프로에이트 5 내지 9%-α-하이드록시-γ-메틸티로부티레이느의 칼슘염, 나트륨염 또는 칼륨염 1 내지 3%L-트립토판 0.1 내지 1%L-티로신 15 내지 20%L-트레오닌 3 내지 7%.
  7. 제6항에 있어서, 조성물을 저단백식이와 함께 투여는 방법.
  8. 제6항에 있어서, 조성물을 투여하기 전에 수성 매질에 용해/현탁시키는 방법.
  9. 제6항에 있어서, 조성물을 투여하기 전에 향미제를 함유하는 수성 매질에 용해/현탁 시키는 방법.
  10. 제6항에 있어서, 조성물을 투여하기 전에 과일 쥬스에 용해/현탁시키는 방법.
  11. 하기 중량%의 하기 성분의 혼합물로 이루어진 조성물.
    L-오르티닌-α-케토이소발레레이트 21 내지 25%L-오르니틴-α-케토이소캐프로에이트 21 내지 25%L-리신-α-케토-β-메틸발레레이트 21 내지 25%L-히스티딘-α-케토이소캐프로에이트 6 내지 8% α-하이드록시-γ-메틸티로부티레이트의 칼슘염, 나트륨염 또는 칼륨염 1.5 내지 2.5%L-트립토판 0.2 내지 0.75%L-티로신 16내지 19%L-트레오닌 4 내지 6%.
  12. 하기 중량%의 하기 성분의 혼합물로 이루어진 조성물.
    L-오르티닌-α-케토이소발레레이트 21 내지 24%L-오르니틴-α-케토-β-메틸발레레이트 21 내지 24%L-리신-α-케토-케토이소케프로에이트 21 내지 24%L-히스티딘-α-케토이소캐프로에이트 6 내지 8%-α-하이드록시-γ-메틸티로부티레이트의 칼슘염, 나트륨염 또는 칼륨염 1.5 내지 25%L-트립토판 0.2 내지 2.5%L-티로신 0.2내지 10.75%L-트레오닌 4 내지 6%.
    ※참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900009129A 1989-06-21 1990-06-21 신장 질환 치료용 영양제제 KR910000140A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/369,163 US4957938A (en) 1989-06-21 1989-06-21 Nutritional formulation for the treatment of renal disease
US369163 2006-03-03

Publications (1)

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KR910000140A true KR910000140A (ko) 1991-01-29

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ID=23454347

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KR1019900009129A KR910000140A (ko) 1989-06-21 1990-06-21 신장 질환 치료용 영양제제

Country Status (9)

Country Link
US (1) US4957938A (ko)
EP (1) EP0405295B1 (ko)
JP (1) JPH0331211A (ko)
KR (1) KR910000140A (ko)
AT (1) ATE91392T1 (ko)
AU (1) AU627041B2 (ko)
CA (1) CA2019472A1 (ko)
DE (1) DE69002201T2 (ko)
ES (1) ES2058687T3 (ko)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374651A (en) * 1991-09-27 1994-12-20 Board Of Regents, The University Of Texas System Methods and compositions for the treatment of hypotension with arginine free essential and essential amino acids and arginine derivatives
EP0663826B1 (en) * 1991-09-27 1998-12-23 Board Of Regents The University Of Texas System Amino acids containing parenteral formulations for the treatment of hypotension and related pathologies
US5234696A (en) * 1991-12-27 1993-08-10 Abbott Laboratories Method of producing tablets, tablets produced thereby, and method of treatment using same
US5891459A (en) 1993-06-11 1999-04-06 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
US5576287A (en) * 1994-04-29 1996-11-19 Wake Forest University Method for treating acute renal disease and failure
JP3539970B2 (ja) * 1994-10-07 2004-07-07 フイルメニツヒ ソシエテ アノニム フレーバリング組成物及びフレーバリング方法
AUPN115095A0 (en) * 1995-02-15 1995-03-09 Butt, Henry Lawrence Analysis of and compositions and methods for the treatment of disease
FR2775901B1 (fr) * 1998-03-13 2000-07-21 Logeais Labor Jacques Sels de cetoacides et de derives amines, et leur utilisation pour la preparation de medicaments
US20050196470A9 (en) * 1998-04-03 2005-09-08 Wuh Hank C Method and composition for enhancing sexual desire
AU3221599A (en) * 1998-04-03 1999-10-25 Daily Wellness Company, The Compositions comprising l-arginine, ginseng and gingko biloba for enhancing blood circulation
US6288116B1 (en) 1998-05-13 2001-09-11 Novartis Nutrition Ag Method of administration of a nutritional product to a person having renal failure
JP2003501393A (ja) * 1999-06-05 2003-01-14 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ 心臓血管細胞増殖を阻害するための方法および組成物
US7696219B2 (en) * 2000-09-27 2010-04-13 Everett Laboratories, Inc. Method and composition for supplementation of nutritional deficiences in renal patients
US6995166B1 (en) 2000-09-27 2006-02-07 Everett Laboratories, Inc. Method and composition for supplementation of nutritional deficiencies in renal patients
US6989164B2 (en) * 2000-12-22 2006-01-24 The Daily Wellness Company Method and composition for improving male fertility health
US6497885B2 (en) * 2000-12-22 2002-12-24 The Daily Wellness Company Method and composition for improving fertility health in female and male animals and humans
FR2822704B1 (fr) * 2001-03-29 2005-02-18 Chiesi Sa Sels de cetoacides et d'acides amines gastroresistants et leur utilisation pour la preparation de medicaments
WO2002081020A2 (en) * 2001-04-04 2002-10-17 Critical Therapeutics, Inc. Method for preventing acute renal failure
ITTO20020672A1 (it) * 2002-07-26 2004-01-26 Medestea Res And Production S Composizioni farmaceutiche contenenti cheto-acidi per somministrazione endoperitoneale
JP2007526316A (ja) * 2004-03-01 2007-09-13 ルーメン セラピューティックス リミテッド ライアビリティ カンパニー 疾患を処置するための組成物および方法

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* Cited by examiner, † Cited by third party
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US4100293A (en) * 1974-04-15 1978-07-11 The Johns Hopkins University Treatment of hepatic disorders with therapeutic compositions comprising keto analogs of essential amino acids
GB1511302A (en) * 1974-04-15 1978-05-17 Univ Johns Hopkins Pharmaceutical compositions comprising amino acid analogues
US4320146A (en) * 1978-03-17 1982-03-16 The Johns Hopkins University Treatment of hepatic and renal disorders with ornithine and arginine salts of branched chain keto acids
US4352814A (en) * 1979-04-18 1982-10-05 The Johns Hopkins University Treatment of hepatic and renal disorders with mixed salts of essential or semi-essential amino acids and nitrogen-free analogs
US4296127A (en) * 1979-04-18 1981-10-20 The Johns Hopkins University Mixed salts of essential or semi-essential amino acids and nitrogen-free analogs thereof
US4677121A (en) * 1985-01-22 1987-06-30 The Johns Hopkins University Method of inhibiting muscle protein degradation
US4752619A (en) * 1985-12-23 1988-06-21 The Johns Hopkins University Nutritional supplement for treatment of uremia
FR2615734B1 (fr) * 1987-05-27 1989-12-01 Synthelabo Compositions pharmaceutiques contenant un melange de sels de cetoacides et d'amino-acides utiles pour le traitement de l'uremie

Also Published As

Publication number Publication date
EP0405295A2 (en) 1991-01-02
JPH0331211A (ja) 1991-02-12
ES2058687T3 (es) 1994-11-01
US4957938A (en) 1990-09-18
AU627041B2 (en) 1992-08-13
DE69002201D1 (de) 1993-08-19
CA2019472A1 (en) 1990-12-21
ATE91392T1 (de) 1993-07-15
DE69002201T2 (de) 1994-01-05
EP0405295B1 (en) 1993-07-14
AU5767390A (en) 1991-01-03
EP0405295A3 (en) 1991-03-27

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