KR900001072B1 - Process for axtraction of cassia tora l. - Google Patents

Abstract

An extraction method of cassia tora L. is provided. Thus, selected cassia tora L. is treated at 150-210oC for a few min, crushed (5-10 mesh), dissolved in water, boiled, and extracted. The cassia tora L. cake is treated with 3-4 times of 30-50% ethanol and extracted with stirring at room temperature for 12-24 hrs to give a final product.

Description

Method of Preparation of Clarifier Extract

The first degree predicate treatment.

Figure 2 Process for producing Cassiae extract 1) Water extract manufacturing process 2) Ethanol extract manufacturing process.

Third process for producing carbonated beverages.

In the present invention, in extracting the active ingredient in the deficiency used as a prescription material such as blue liver, nominal blood pressure, constipation, etc. in one shot, while the pharmacological components are almost extracted at room temperature, waterproof and storage properties , Relates to a method for preparing the extract of the Clarifier to enable mass extraction.

Cassia tora L, is a 1 year-old herb belonging to the legumes. In general, the deficiency is slightly roasted, put it in water, and boiled it to make tea. The color is yellowish brown, the taste is slightly bitter, and the smell smells like aloe, so it is inferior to other teas in color and flavor.

The pharmacological components of the deficiencies introduced in Oriental medicine include vitamin A precursor (Carotene (C40 h56)), yellow alloin (C21 H22 O4) with aloe flavor and bitter taste, and Rhein (C15 H8 O6) with yellow color. And Emodin (C15 H10 O5), Chrysophanol, Aloe-emodin, physcion, Obtusin, Aurantio-obtusin, Rubrofusarin, torachryson, Toralactone and so on.

The pharmacological effect of these ingredients is that Carotene is an essential ingredient for optic nerve stimulation and delivery, and it is effective for maintaining good vision, and Alloin is known to lower blood Cholesterol content and to lower blood pressure.

Comprehensive effect of other deficiency is to help the diuretic effect of liver and kidneys, and intestinal fever to prevent constipation effect.

In view of the fact that the defectors have the characteristics of ingredients and until now, the use of them is surprisingly low. This low availability is not because the drinking tea is not simplified, and the soft drink type of beverage is not provided with characteristics that meet the taste of consumers with high preference. In recent years, the number of children and students with low vision has been increasing rapidly, and students are suffering from hypertension, arteriosclerosis and stroke due to not only overworked students, but also constipation due to tension. Popularization of the missing car is very desirable.

By the way, each household currently boils the defector with water and uses it as a tea of tea, but even if the pharmacological ingredients contained in the fruit are boiled with water at 100 ℃, the pharmacological ingredients in the family have -OH and -COOH in the structure. It is slightly soluble in polar solvents such as water, ethanol and methanol. However, when water is used as an extractant, it is required to heat at 100 ° C for a long time, so that the elution is slightly increased. This requires a lot of heating energy and difficulty in management. However, since high temperature heating is performed for a long time, pharmacological components are destroyed and halved, and when extracted as methanol, harmful substances remain in the extract, which is harmful. In addition, when boiled and extracted with water, starch or protein is dispersed in the solution, and even the filtered supernatant contains a large amount of suspended solids, so that the unique color of the deficiency tea cannot be clearly seen. After that, there is the hassle of forced filtering of suspended solids. Because of the above problems, there was a flaw in the lighting, which was not popularized despite the excellent pharmacological action.

)의 유도체들로 극성기인 -OH 기나 -COOH 기를 가지고 있고 분자의 일부에는 CH₃-, CH₃O-를 가지고 있어서 극성물질과 비극성물질을 공히 녹일수 있는 용제가 이상적이다. 이러한 용제들은 아세톤(acetone), 메탄올(methanol), 에탄올(ethanol)을 들수 있으나 에탄올을 제외하고는 잔유물질이 유해하므로 결명자 추출물을 얻기 위해서는 에탄올이 적합하다. 본 발명에서는, 결명자내의 약리적 성분을 추출하기 위한 용제로서 에탄올을 사용하되, 정선된 결명자를 150-210℃에서 수분간 배소한후 5-10메쉬로 분쇄한 결명자 가루에다 농도가 30-50%인 에탄올을 상기 결명자 가루의 중량에 대하여 부피가 5-10배되게 첨가하여 12-24시간동안 가끔 교반하면서 약리적 성분을 추출하는 것이며, 또한, 경제적인 추출을 하기 위하여, 정선된 결명자를 150-210℃에서 수분간 배소한후 5-10메쉬로 분쇄하여 일차로 물을 가한 후 100℃로 끓여 수 추출액을 얻고, 이때 발생한 결명자박에다 농도가 30-50%인 에탄올을 상기 결명자 가루의 중량에 대하여 부피가 3-4배되게 첨가하여 12-24시간동안 교반하면서 이차추출하여 에탄올 추출액을 얻는 것을 특징으로 하는 결명자 추출물의 제조방법을 제공하고자 하는 것이다.The present invention is to solve this drawback, that is to extract a large amount of pharmacological components in the Clarifier at room temperature almost in a large amount, the clearness of the extraction solution is excellent filtration process is easy, at the same time excellent antiseptic, good storage ability To obtain a phase or granular extract of the defect. The active ingredients contained in the deficiency are oxyanthraquinone (

Derivatives of) have polar groups -OH group or -COOH group, and some of the molecules have CH _3- , CH ₃ O-, so the solvent that can dissolve both polar and non-polar materials is ideal. These solvents may include acetone, methanol and ethanol. However, except for ethanol, residual substances are harmful, so ethanol is suitable for obtaining a deficiency extract. In the present invention, ethanol is used as a solvent for extracting pharmacological components in the cultivars, but the concentration of the spermatozoa pulverized with 5-10 mesh after roasting the selected spermatozoa at 150-210 ° C. for several minutes is 30-50%. Ethanol is added to a volume of 5 to 10 times the weight of the grains of the clarifier to extract the pharmacological component with occasional stirring for 12-24 hours, and also, in order to economically extract, the selected deflector 150-210 ℃ After roasting for several minutes at 5-10 mesh pulverized water was added first and then boiled at 100 ℃ to obtain a water extract, and the ethanol of 30-50% concentration in the deficiency of the deficiency of the deficiency powder Is added to be 3-4 times to stir for 12-24 hours while stirring to provide a method for the preparation of the deflector extract, characterized in that to obtain an ethanol extract.

As mentioned above, the pharmacological components in the deflector have several hydroxyl groups (OH), which elute well as ethanol, and at the same time, ethanol is insoluble by denaturing suspended matters such as proteins, so that even if a rich substance of protein is generated, Since it precipitates, yellowish brown, which is a unique natural color of the pharmacological component, appears clearly, and the extract obtained by ethanol has good preservatives because of its preservative property, and has an advantage of allowing instant extraction of the extract during long-term storage.

In addition, the process is easy, convenient, and easy to manage because it extracts the active ingredient in the defect at room temperature, it is more economical than heat extraction because a large amount of extract can be obtained without too long. The extract obtained as described above is taken as a water-free car when it is intact, and it can be concentrated under reduced pressure at 70-80 ° C to obtain an aqueous phase, and when it is spray-dried, it can be granular. It can be easily purchased and can popularize the faulty car.

Such extracts can be carbonated beverages, which can also be used as a raw material of carbonated beverages prepared by the method.

Example 1

In the same process as in FIG. 1 and FIG. 2, 1), roast the deflector at 150-210 ° C., and crush it with 5-10 mesh. 10 g of water and 1.5 l of water are added and boiled for 1 hour, followed by filtration. Tea extract). At this time, it is important to extract the active ingredient in the missing name, and the degree of extraction of the active ingredient was determined by Lovibond colorimeter (Tintometer Model E AF 900). Redness (R), yellowness (Y), and blueness (B) were 1.9, 19.9, and 0.2, respectively. It was.

Example 2

The ethanol extract was obtained through 2) of FIG. That is, there are Carotene, alloin, Emodin, etc., which are not well eluted in water, so that the active ingredient still remains in the foil generated when obtaining the primary extract in Example 1. Thus, the ethanol having a concentration of 30-50% was added to the gourd obtained in the preparation of the extract so that the volume was 3-4 times (weight-to-volume) with respect to the weight of the gourd gourd, and extracted for 12-24 hours. As a result, a yellowish brown extract having redness (R), yellowness (Y), and blueness (B) of 9.9, 45.9, and 1.1, respectively. These results indicate that the active ingredient contained in the defecter tissue contains a lot of ethanol soluble components that are not easily extracted by hot water extraction alone. At this time, the obtained liquid as a secondary extract (ethanol extract) and obtained as in Example 1 as a primary extract (water extract) by combining this primary and secondary extracts obtained a carbonated beverage according to the carbonated beverage manufacturing process as shown in FIG. Results The redness (R), yellowness (Y), and blueness (B) are 5.6, 25.2, and 0.9, respectively. Therefore, when manufacturing the clarifier tea (also called undercarriage) from the cultivator or the cultivating carbonated beverage, the extraction rate of the active ingredient in the cultivator is very low. Can be used in parallel.

However, the pharmacological components of the fault is a problem that causes a decrease in efficacy by heating the pharmacological components by extracting at a high temperature by heating 1-2 hours at a high temperature of about 100 ℃.

Example 3

2, using the ethanol solution having a lower boiling point than water and having a polarity and dissolving both water-soluble and non-water-soluble components in the crystallized according to the process of FIG. Cold extracted.

In other words, the selected deflector was roasted for several minutes at 150-210 ° C. to remove the odor, pulverized with 5-10 mesh, and 5-10 times 30-50% ethanol was added to the deflector powder, followed by cold extraction while stirring at room temperature. After 2) to obtain an ethanol extract. The chromaticity of the liquid obtained at this time is red (R), yellow (Y), and blue (B) of 10.6, 52.2, and 1.1, respectively. It can be seen that.

In addition, the extract obtained by this process contains a component having a polarity and a component having no polarity, so that the extract has a large pharmacological effect because it uses a cold acupuncture method rather than a high temperature extraction as in water extraction.

Claims (2)

The selected crystallizer was roasted at 150-210 ℃ for several minutes, pulverized with 5-10 mesh, added with water, boiled to obtain a water extract, and the ethanol having a concentration of 30-50% was added to the weight of the crystallizer foil. Method for producing a deflector extract, characterized in that to obtain a secondary extract (ethanol extract) while stirring for 12-24 hours by adding a volume 3-4 times the relative volume. The selected crystallizer was roasted at 150-210 ° C. for several minutes, and then ethanol having a concentration of 30-50% was added to the crystallized powder, which was pulverized with 5-10 mesh, to obtain the extract liquid by 5-10 times the volume of the crystallized powder. Method for producing a Clarifier extract, characterized in that.

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