KR900000346A - N-술파모일-3-[(2-구아니디노티아졸-4-일)메틸티오]프로피온 아미딘 유도체의 제조방법 - Google Patents

N-술파모일-3-[(2-구아니디노티아졸-4-일)메틸티오]프로피온 아미딘 유도체의 제조방법 Download PDF

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Publication number
KR900000346A
KR900000346A KR1019880006994A KR880006994A KR900000346A KR 900000346 A KR900000346 A KR 900000346A KR 1019880006994 A KR1019880006994 A KR 1019880006994A KR 880006994 A KR880006994 A KR 880006994A KR 900000346 A KR900000346 A KR 900000346A
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KR
South Korea
Prior art keywords
formula
compound
preparing
guanidinothiazol
sulfamoyl
Prior art date
Application number
KR1019880006994A
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English (en)
Other versions
KR900004907B1 (ko
Inventor
고문규
신재무
김동수
이춘석
Original Assignee
우대규
한일약품공업 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 우대규, 한일약품공업 주식회사 filed Critical 우대규
Priority to KR1019880006994A priority Critical patent/KR900004907B1/ko
Priority to JP63190770A priority patent/JPH01313471A/ja
Priority to GB8820830A priority patent/GB2220415B/en
Priority to DE3831162A priority patent/DE3831162A1/de
Publication of KR900000346A publication Critical patent/KR900000346A/ko
Application granted granted Critical
Publication of KR900004907B1 publication Critical patent/KR900004907B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

내용 없음.

Description

N-술파모일-3-[(2-구아니디노티아졸-4-일)메틸티오] 프로피온 아미딘 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 다음 구조식(II)의 이미데이트 화합물과 다음 구조식(III)의 술파미드 화합물을 비양자성 용매에서 반응시킴을 특징으로 하는 다음 구조식(IV)의 화합물의 제조방법.
    (상기 구조식에서 R1은 메틸·에틸등의 저급 알킬기이고, R2는 트리메틸실릴기, t-부틸디메틸실릴기등의 저급 트리알킬실릴기이다).
  2. 다음 구조식(I)의 화합물을 상기 일반식(IV)의 화합물으로부터 탈실릴화 반응시켜 제조함을 특징으로 하는 다음 구조식(I)의 화합물의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880006994A 1988-06-10 1988-06-10 N-술파모일-3-[(2-구아니디노티아졸-4-일)메틸티오]프로피온 아미딘 유도체의 제조방법 KR900004907B1 (ko)

Priority Applications (4)

Application Number Priority Date Filing Date Title
KR1019880006994A KR900004907B1 (ko) 1988-06-10 1988-06-10 N-술파모일-3-[(2-구아니디노티아졸-4-일)메틸티오]프로피온 아미딘 유도체의 제조방법
JP63190770A JPH01313471A (ja) 1988-06-10 1988-08-01 Ｎ−スルフアモイルアミジン化合物の製造法
GB8820830A GB2220415B (en) 1988-06-10 1988-09-05 Process for producing a sulphamide
DE3831162A DE3831162A1 (de) 1988-06-10 1988-09-13 Verfahren zur herstellung von 3-(((2-(diaminomethylen)amino)-4-thiazolyl)methyl)thio-n-sulfamoylpropionamidin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019880006994A KR900004907B1 (ko) 1988-06-10 1988-06-10 N-술파모일-3-[(2-구아니디노티아졸-4-일)메틸티오]프로피온 아미딘 유도체의 제조방법

Publications (2)

Publication Number Publication Date
KR900000346A true KR900000346A (ko) 1990-01-30
KR900004907B1 KR900004907B1 (ko) 1990-07-09

Family

ID=19275113

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880006994A KR900004907B1 (ko) 1988-06-10 1988-06-10 N-술파모일-3-[(2-구아니디노티아졸-4-일)메틸티오]프로피온 아미딘 유도체의 제조방법

Country Status (4)

Country Link
JP (1) JPH01313471A (ko)
KR (1) KR900004907B1 (ko)
DE (1) DE3831162A1 (ko)
GB (1) GB2220415B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731442A (en) * 1997-03-11 1998-03-24 Albemarle Corporation Synthesis of thiazole derivatives
US5856500A (en) * 1997-03-11 1999-01-05 Albemarle Corporation Synthesis of thiazole derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59227870A (ja) * 1983-06-07 1984-12-21 Yamanouchi Pharmaceut Co Ltd 新規２−グアニジノチアゾリン誘導体ならびにその製造法
DE3644246A1 (de) * 1986-06-20 1987-12-23 Uriach & Cia Sa J Verfahren zur herstelung von 3-(((2-((aminoiminomethyl)-amino)-4-thiazolyl)-methyl)-thio)-n-(aminosulfonyl)-propanimidamid

Also Published As

Publication number Publication date
DE3831162C2 (ko) 1992-02-20
GB2220415A (en) 1990-01-10
DE3831162A1 (de) 1989-12-14
JPH01313471A (ja) 1989-12-18
KR900004907B1 (ko) 1990-07-09
GB8820830D0 (en) 1988-10-05
GB2220415B (en) 1991-12-18

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