KR890701145A - 의료용 기구 및 그 제조방법 - Google Patents

의료용 기구 및 그 제조방법

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Publication number
KR890701145A
KR890701145A KR1019890700886A KR890700886A KR890701145A KR 890701145 A KR890701145 A KR 890701145A KR 1019890700886 A KR1019890700886 A KR 1019890700886A KR 890700886 A KR890700886 A KR 890700886A KR 890701145 A KR890701145 A KR 890701145A
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membrane
surfactant
blood
medical device
hollow fiber
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KR1019890700886A
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KR930003334B1 (ko
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아쓰히꼬 노가와
오사무 노무라
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도자와 미쓰오
데루모 가부시끼가이샤
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0088—Physical treatment with compounds, e.g. swelling, coating or impregnation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0017—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using a surface active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698—Blood oxygenators with or without heat-exchangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3623—Means for actively controlling temperature of blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B01D63/0233—Manufacturing thereof forming the bundle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/10—Testing of membranes or membrane apparatus; Detecting or repairing leaks
    • B01D65/104—Detection of leaks in membrane apparatus or modules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/03—Heart-lung
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S261/00—Gas and liquid contact apparatus
    • Y10S261/28—Blood oxygenators

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Manufacturing & Machinery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)

Abstract

내용 없음

Description

의료용 기구 및 그 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1 도는 본 발명의 의료용 기구를 막형 인공폐에 응용한 일 실시예의 단면도이다. 제 2 도는 본 발명의 의료용 기구를 열교환기 및 저혈조를 취부(取付)한 막형 인공폐 장치에 응용한 일 실시예의 부분 단면도이다. 제 3 도는 본 발명의 의료용 기구를 혈액 필터에 응용한 일 실시예의 부분 단면도이다.

Claims (14)

  1. 소수성 재료로서된 혈액 접촉부를 갖는 의료용 기구의 그 혈액 접촉부의 일부 또는 전부에 생체에 안전한 계면 활성제를 부착시킨 것을 특징으로 하는 의료용 기구.
  2. 제 1 항에 있어서, 상기 의료용 기구가, 가스 교환막으로서 소수성막을 사용한 막형 인공폐이며, 그 막형 인공폐 내부의 혈액 접촉부의 일부 또는 전부에 상기 계면 활성제가 부착되어 있는 의료용 기구.
  3. 제 1 항에 있어서, 상기 의료용 기구가, 소수성막을 사용한 혈액필터이며, 그 혈액필터 내부의 혈액 접촉부의 일부 또는 전부에 상기 계면 활성제가 부착되어 있는 의료용 기구.
  4. 제 1 항에 있어서, 상기 계면 활성제가, 바이온계 계면 활성제인 의료용 기구.
  5. 제 1 항에 있어서, 상기 계면 활성제가, 폴리에텔형 고분자 계면 활성제인 의료용 기구
  6. 제 2 항에 있어서, 상기 가스 교환막이 다공질막인 의료용 기구.
  7. 제 2 항에 있어서, 상기 가스 교환막이 다공질 중공사막인 의료용 기구.
  8. 제 2 항에 있어서, 상기 막형 인공폐가, 혈액 유입구와 혈액 유출구를 갖는 하우징과 그 하우징내에 수납된 다수의 가스교환용 중공사막으로된 중공사막속과, 그 중공사막속(中空系膜束)의 양단부를 상기한 하우징에 액밀하게 지지하는 한쌍의 격벽을 가지며, 그 격벽과 상기한 하우징 내면 및 상기한 중공사막 외면에 의해 형성된 혈액실과, 상기한 중공사막 내부에 형성된 가스실을 가지며, 다시 적어도 어느것인가 한쪽의 격벽의 외측에 설치되며, 상기한 가스실과 연통하는 가스 유입구를 갖는 가스 유로형성체를 갖는 의료용 기구.
  9. 소수성 재료로서된 혈액 접촉부를 갖는 의료용 기구를 조립한 후, 그 혈액접촉부에, 생체에 안전한 계면 활성체를 함유한 액체를 접촉시키고, 다시 건조시켜서, 상기한 혈액접촉부의 표면에 상기한 계면 활성제를 부착시키는 것을 특징으로 하는 의료용 기구의 제조방법.
  10. 제 9 항에 있어서, 상기 의료용 기구가, 하우징내에 수납된 소수성 가스 교환막에 의해 하우징내가 혈액실과 가스실로 구획된 막형 인공폐이며, 그 막형 인공폐를 조립한 후, 상기 혈액실내에 계면 활성제를 첨가한 용액을 충전하고, 다시 혈액실측을 가압 상태 혹은 가스실측을 음압(陰壓)으로 한후, 상기 용액을 제거하여 건조하는 것을 특징으로 하는 의료용 기구의 제조방법.
  11. 제 10항에 있어서, 상기 가스 교환막이 다공질막인 의료용 기구의 제조방법.
  12. 제 10항에 있어서, 상기 막형 인공폐가, 하우징과 그 하우징내에 수납된 다수의 가스 교환용 중공사막으로된 중공사막속과, 그 중공사막속의 양단부를 상기한 하우징에 액밀하게 지지하는 한쌍의 격벽과 그 격벽과 상기한 하우징 내면 및 상기한 중공사막 외면에 의해 형성된 혈액실과, 상기한 중공사막 내부에 형성된 가스실을 가지며, 다시, 적어도 어느것인가 한쪽의 격벽의 외측에 설치되며, 상기한 가스실과 연통하는 유입구를 갖는 가스 유로형성체를 갖는 의료용 기구의 제조방법.
  13. 제 9 항에 있어서, 상기 계면 활성제가 바이온계 계면 활성제인 의료용 기구의 제조방법.
  14. 제 9 항에 있어서, 상기 계면 활성제가, 폴리에텔형 고분자 계면 활성제인 의료용 기구의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890700886A 1987-09-21 1988-09-16 의료용 기구 및 그 제조방법 KR930003334B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP23486087 1987-09-21
JP234,860 1987-09-21
JP62-234860 1987-09-21
PCT/JP1988/000936 WO1989002282A1 (en) 1987-09-21 1988-09-16 Medical instrument and production thereof

Publications (2)

Publication Number Publication Date
KR890701145A true KR890701145A (ko) 1989-12-19
KR930003334B1 KR930003334B1 (ko) 1993-04-26

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KR1019890700886A KR930003334B1 (ko) 1987-09-21 1988-09-16 의료용 기구 및 그 제조방법

Country Status (8)

Country Link
US (1) US5162102A (ko)
EP (1) EP0381757B1 (ko)
JP (1) JP2610042B2 (ko)
KR (1) KR930003334B1 (ko)
AU (1) AU616212B2 (ko)
CA (1) CA1340585C (ko)
DE (1) DE3879218T2 (ko)
WO (1) WO1989002282A1 (ko)

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DE3879218D1 (de) 1993-04-15
EP0381757A1 (en) 1990-08-16
JP2610042B2 (ja) 1997-05-14
AU2382588A (en) 1989-04-17
AU616212B2 (en) 1991-10-24
EP0381757A4 (en) 1990-09-05
DE3879218T2 (de) 1993-07-22
WO1989002282A1 (en) 1989-03-23
KR930003334B1 (ko) 1993-04-26
US5162102A (en) 1992-11-10
EP0381757B1 (en) 1993-03-10
CA1340585C (en) 1999-06-08

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