KR890009876A - 9-아실아미노- 테트라히드로아크리딘 유도체 및 그 유도체를 활성성분으로 포함하는 기억력 촉진제 - Google Patents
9-아실아미노- 테트라히드로아크리딘 유도체 및 그 유도체를 활성성분으로 포함하는 기억력 촉진제 Download PDFInfo
- Publication number
- KR890009876A KR890009876A KR1019880016146A KR880016146A KR890009876A KR 890009876 A KR890009876 A KR 890009876A KR 1019880016146 A KR1019880016146 A KR 1019880016146A KR 880016146 A KR880016146 A KR 880016146A KR 890009876 A KR890009876 A KR 890009876A
- Authority
- KR
- South Korea
- Prior art keywords
- derivatives
- acylamino
- tetrahydroacridine
- promoter
- memory
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
- C07D219/12—Amino-alkylamino radicals attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 하기 일반식(Ⅰ)으로 표현되는 9-아실아미노- 테트라히드로아크리딘 유도체, 유도체의 광학적 대장체 또는 약리적으로 허용되는 그의 산 부가염 ;상기 식에서, R은 알킬기, 아르알킬기 또는 하기 일반식(Ⅱ)로 표현되는 기임 :상기식(Ⅱ)에서, R1은 수소원자 또는 알킬기이며, R2는 수소원자OR3(여기서, R3는 수소원자 또는 알킬기임) 또는R2가 서로 결합되어
- 제1항에 있어서, R이 일반식(Ⅱ)로 표현되는 화합물.
- 활성성분으로서 콜린성 신경에 대한 고-친화성 콜린 흡수 작용을 중진시키는 역할을 하는 9-아실아미노-테트라히드로아크리딘 유도체, 그 유도체의 광학적 대장체 또는 약리적으로 허용되는 그의 산 부가염을 함유하는 기억력 촉진제.
- 제1항에서 정의된 일반식(Ⅰ)의 9-아실아미노-테트라히드로아크리딘 유도체, 그 유도체의 광학적 대장체 또는 약리적으로 허용되는 그의 산 부가염을 활성성분으로 포함하는 기억력 촉진제.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP30675387 | 1987-12-03 | ||
JP62-306753 | 1987-12-03 | ||
JP63283351A JPH01250353A (ja) | 1987-12-03 | 1988-11-09 | 9−アシルアミノ−テトラヒドロアクリジン誘導体及び該誘導体を有効成分とする記憶障害改善剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR890009876A true KR890009876A (ko) | 1989-08-04 |
KR0128975B1 KR0128975B1 (ko) | 1998-04-09 |
Family
ID=26555006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880016146A KR0128975B1 (ko) | 1987-12-03 | 1988-12-03 | 9-아실아미노-테트라히드로아크리딘 유도체 및 그 유도체를 활성 성분으로 포함하는 기억력 촉진제 |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPH01250353A (ko) |
KR (1) | KR0128975B1 (ko) |
HU (1) | HU202499B (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2720549B2 (ja) * | 1989-11-08 | 1998-03-04 | 三菱化学株式会社 | 9―アミノアセチルアミノテトラヒドロアクリジン誘導体 |
JP2546919B2 (ja) * | 1989-11-08 | 1996-10-23 | 三菱化学株式会社 | 9ーアシルアミノテトラヒドロアクリジン誘導体 |
AU2011232058B2 (en) * | 2010-03-26 | 2016-09-08 | Merck Patent Gmbh | Benzonaphthyridinamines as autotaxin inhibitors |
-
1988
- 1988-11-09 JP JP63283351A patent/JPH01250353A/ja active Pending
- 1988-12-02 HU HU886151A patent/HU202499B/hu not_active IP Right Cessation
- 1988-12-03 KR KR1019880016146A patent/KR0128975B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR0128975B1 (ko) | 1998-04-09 |
JPH01250353A (ja) | 1989-10-05 |
HU202499B (en) | 1991-03-28 |
HUT50460A (en) | 1990-02-28 |
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