KR890002409A - 케톤의 환원방법 - Google Patents

케톤의 환원방법 Download PDF

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Publication number
KR890002409A
KR890002409A KR1019880009015A KR880009015A KR890002409A KR 890002409 A KR890002409 A KR 890002409A KR 1019880009015 A KR1019880009015 A KR 1019880009015A KR 880009015 A KR880009015 A KR 880009015A KR 890002409 A KR890002409 A KR 890002409A
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South Korea
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carbon atoms
hal
alkyl
het
iii
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KR1019880009015A
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English (en)
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라던쯔 한스-에카르트
슈바르츠 해리
하인리히 마틴
Original Assignee
나우만,호이만
메르크 라덴트 게젤샤프트 베슈랭크러 하프통
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Application filed by 나우만,호이만, 메르크 라덴트 게젤샤프트 베슈랭크러 하프통 filed Critical 나우만,호이만
Publication of KR890002409A publication Critical patent/KR890002409A/ko

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    • C—CHEMISTRY; METALLURGY
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
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    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Abstract

내용 없음

Description

케톤의 환원방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 미생물에 의해 2급알콜을 생성시키기 위해 케토 화합물의 호변 선택적 환원방법에 있어서, 다음 일반식(Ⅰ)의 화합물을 출발화합물로서 사용함을 특징으로 하는 호변 선택적 환원방법
    R3NH-CHR1-CO-CH2-COOR2(Ⅰ)
    상기식에서 R1은 A, Ar, Ar-알킬, HeT, HeT-알킬, 비치환 또는 A, AO 및/또는 Hal로 일치환 또는 다치환 된 탄화수소 3 내지 7의 시클로알킬, 탄소수 4 내지 11의 시클로알킬알킬, 탄소수 7 내지 14의 비시클로알킬 또는 탄소수 8 내지 18의 비시클로알킬알킬이고, R2는 H 또는 탄소수 1 내지 5의 알킬이고, R3는 H, 벤질, 트리페틸메틸, 벤질옥시카보닐, 3급-부틸옥시카보닐 또는 9-플루오레닐메톡시카보닐이고, Ar은 비치환 또는 A, AO, Hal, CF3, HO, 탄소수 1 내지 8의 히드록시알킬, Het는 벤젠링과 융합할 수 있는 1 내지 4의 N, O 및/또는 S원자를 갖고/갖거나, A, AO, Hal, CF3, HO, O2N, 카보닐산소, H2N,HAN, A2N, AS, ASO, ASO2,AOOC, CN, H|uNCO, HOOC, HNSO, ASONH, Ar, Ar懦케닐, 각기 탄소수 1 내지 8을 갖는 히드록시알킬 및/또는 아미노알킬로 일치환 또는 다치환된, 포화 또는 불포화 5-또는 6원 헤테로시클릭래디칼이고/이거나, N 및/또는 S 헤테로원자는 산화될 수도 있고, Hal은 F, Cl, Br 또는 I이고, Ac는 A-CO-, Ar-CO- 또는 A-NH-CO-이고, A는 탄소수 1 내지 8의 알킬이다.
  2. 다음 구조성분(Ⅲ)을 함유하는 레닌 억제제를 합성하는데 있어서의 다음 일반식(Ⅲ)의 화합물의 용도.
    R3NH-CHR1-CHOH-CH2-COOR2(Ⅱ) -NH-CH-CHOH-CH2-CO- (Ⅲ)
    상기 식에서 R1내지 R3는 제1항에서 정의한 바와 같다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880009015A 1987-07-22 1988-07-19 케톤의 환원방법 KR890002409A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873724197 DE3724197A1 (de) 1987-07-22 1987-07-22 Verfahren zur reduktion von ketonen
DEP3724197.4 1987-07-22

Publications (1)

Publication Number Publication Date
KR890002409A true KR890002409A (ko) 1989-04-10

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ID=6332081

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Application Number Title Priority Date Filing Date
KR1019880009015A KR890002409A (ko) 1987-07-22 1988-07-19 케톤의 환원방법

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US (1) US5026642A (ko)
EP (1) EP0300287B1 (ko)
JP (1) JPS6455187A (ko)
KR (1) KR890002409A (ko)
AR (1) AR240064A1 (ko)
AT (1) ATE84317T1 (ko)
AU (1) AU628289B2 (ko)
DD (1) DD272475A5 (ko)
DE (2) DE3724197A1 (ko)
DK (1) DK409388A (ko)
ES (1) ES2043738T3 (ko)
FI (1) FI883457A (ko)
HU (1) HU203905B (ko)
ZA (1) ZA885365B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100411685B1 (ko) * 2001-10-31 2003-12-18 (주)그린앤크린 대두지방산과 레시틴을 이용한 활성 수용성 천연세제조성물 및 그 제조방법

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232853A (en) * 1989-12-28 1993-08-03 Takeda Chemical Industries, Ltd. Method for producing (2r,3s)-3-hydroxy-2-methylbutyrate by microbial reduction
US5215919A (en) * 1991-02-25 1993-06-01 Takeda Chemical Industries, Ltd. Process for producing optically active 2-hydroxycycloalkanecarboxylic acid esters using microbially derived reductase
WO1993007289A1 (en) * 1991-10-04 1993-04-15 Schering Corporation ENZYMATIC SYNTHESIS OF CHIRAL α-HYDROXYKETONES AND DERIVATIVES
DE4209022B4 (de) * 1992-03-20 2006-01-19 Forschungszentrum Jülich GmbH Verfahren zur enzymatischen Herstellung von sekundären (S)-Alkoholen
US5324662A (en) * 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters
CA2103932A1 (en) * 1992-11-05 1994-05-06 Ramesh N. Patel Stereoselective reduction of ketones
GB9512837D0 (en) * 1995-06-23 1995-08-23 Zeneca Ltd reduction of ketone groups
JP2002513573A (ja) 1998-05-07 2002-05-14 ドゥーサン コーポレーション ピヒア・シフェリにおける遺伝子発現のためのプラスミド及びこれを用いた形質転換方法
US10784121B2 (en) 2016-08-15 2020-09-22 Xilinx, Inc. Standalone interface for stacked silicon interconnect (SSI) technology integration

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4478826A (en) * 1981-10-08 1984-10-23 Merck & Co., Inc. Renin inhibitory peptides
CA1258748A (en) * 1981-10-08 1989-08-22 Daniel F. Veber Renin inhibitory peptides
EP0104041B1 (en) * 1982-09-15 1988-07-27 Aktiebolaget Hässle Enzyme inhibitors
US4650661A (en) * 1982-09-15 1987-03-17 Aktiebolaget Hassle Enzyme inhibitors
US4477440A (en) * 1983-09-14 1984-10-16 Merck & Co., Inc. Renin inhibitors containing an n-terminal disulfide cycle
KR870005013A (ko) * 1985-11-29 1987-06-04 가와무라 요시부미 레닌-억제 올리고펩티드, 그의 제조방법 및 용도

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100411685B1 (ko) * 2001-10-31 2003-12-18 (주)그린앤크린 대두지방산과 레시틴을 이용한 활성 수용성 천연세제조성물 및 그 제조방법

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Publication number Publication date
DK409388D0 (da) 1988-07-21
ZA885365B (en) 1989-03-29
DE3724197A1 (de) 1989-02-02
FI883457A (fi) 1989-01-23
JPS6455187A (en) 1989-03-02
EP0300287A2 (de) 1989-01-25
AR240064A1 (es) 1990-01-31
ES2043738T3 (es) 1994-01-01
FI883457A0 (fi) 1988-07-21
EP0300287B1 (de) 1993-01-07
HU203905B (en) 1991-10-28
HUT47642A (en) 1989-03-28
AU1823288A (en) 1989-01-27
DK409388A (da) 1989-01-23
DD272475A5 (de) 1989-10-11
EP0300287A3 (en) 1989-05-03
AU628289B2 (en) 1992-09-17
ATE84317T1 (de) 1993-01-15
US5026642A (en) 1991-06-25
DE3877275D1 (de) 1993-02-18

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