KR880000596A - 효소 센서 - Google Patents

효소 센서 Download PDF

Info

Publication number
KR880000596A
KR880000596A KR1019870006187A KR870006187A KR880000596A KR 880000596 A KR880000596 A KR 880000596A KR 1019870006187 A KR1019870006187 A KR 1019870006187A KR 870006187 A KR870006187 A KR 870006187A KR 880000596 A KR880000596 A KR 880000596A
Authority
KR
South Korea
Prior art keywords
enzyme
sensor according
concentration
measures
enzyme sensor
Prior art date
Application number
KR1019870006187A
Other languages
English (en)
Other versions
KR890004367B1 (ko
Inventor
슈우이찌로오 야마구찌
마사또 우찌다
다께시 시모무라
노보루 고야마
Original Assignee
도자와 미쓰오
데루모 가부시끼 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 도자와 미쓰오, 데루모 가부시끼 가이샤 filed Critical 도자와 미쓰오
Publication of KR880000596A publication Critical patent/KR880000596A/ko
Application granted granted Critical
Publication of KR890004367B1 publication Critical patent/KR890004367B1/ko

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/58Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving urea or urease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/004Enzyme electrodes mediator-assisted
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/817Enzyme or microbe electrode

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

내용 없음

Description

효소 센서
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도 (a)는 실시에 1의 효소 센서의 구성 모식도.
제2도 (b)는 실시에 2의 효소 센서의 구성 모식도.
제3도 (c)는 실시에 3의 효소 센서의 구성 모식도.
제2도는 본 실시예의 효소 센서에 의한 측정 회로예도.
제3도는 실시에 1의 효소 센서에 의한 측정 결과를 나타낸 도면.

Claims (43)

  1. 효소의 분자 식별 기능에 의하여 소정의 기질 농도를 측정하는 효소 센서에 있어서, 도전성 기체와, 이 도전성 기체의 표면을 덮고 상기 기질의 화학반응을 촉진하는 효소로써 된 효소층을 갖고, 상기 도전성 기체의 전위에 의하여 상기 기질의 농도를 측정함을 특징으로 하는 효소 센서.
  2. 제1항에 있어서, 효소는 글루코오즈 옥시다제로서, 글루코오즈의 농도를 측정함을 특징으로 하는 효소 센서.
  3. 제1항에 있어서, 효소는 우레아제로서, 요소의 농도를 측정함을 특징으로 하는 효소 센서.
  4. 제1항에 있어서, 효소는 우리카제로서, 요산의 농도를 측정함을 특징으로 하는 효소 센서.
  5. 제1항에 있어서, 효소는 콜레스테롤 옥시다제로서, 콜레스테롤의 농도를 측정함을 특징으로 하는 효소 센서.
  6. 제1항에 있어서, 효소는 가교제에 의하여 가교 구조로 되어 있음을 특징으로 하는 효소 센서.
  7. 제1항에 있어서, 도전성 기체는 그라파이트 구조의 탄소임을 특징으로 하는 효소 센서.
  8. 효소의 분자 식별 기능에 의하여 소정의 기질의 농도를 측정하는 쇼소 센서에 있어서, 도전성 기체와, 이 도전성 기체의 표면을 덮고 산화환원 기능을 갖는 산화환원 기능층과, 이 산화환원 가능층의 표면을 덮고 상기 기질의 화학반응을 촉진하는 효소로써 된 효소층을 갖고, 상기 도전성 기체의 전위에 의하여 상기 기질의 농도를 측정함을 특징으로 하는 효소 센서.
  9. 제8항에 있어서, 효소는 글루코오즈 옥시다제로서, 글루코오즈의 농도를 측정함을 특징으로 하는 효소 센서.
  10. 제8항에 있어서, 효소는 우레아제로서, 요소의 농도를 측정함을 특징으로 하는 효소 센서.
  11. 제8항에 있어서, 효소는 우리카제로서, 요산의 농도를 측정함을 특징으로 하는 효소 센서.
  12. 제8항에 있어서, 효소는 콜레스테롤 옥시다제로서, 콜레스테롤의 농도를 측정함을 특징으로 하는 효소 센서.
  13. 제8항에 있어서, 효소는 가교제에 의하여 가교 구조로 되어 있음을 특징으로 하는 효소 센서.
  14. 제8항에 있어서, 도전성 기체는 그라파이트 구조의 탄소임을 특징으로 하는 효소 센서.
  15. 제8항에 있어서, 산화환원 기능층은 퀴논-하이드로 퀴논형의 산화환원 기능을 갖는 물질의 그룹으로부터 선택됨을 특징으로 하는 효소 센서.
  16. 제8항에 있어서, 산화환원 기능층은 아민-퀴노이드형의 산화환원 가능을 갖는 물질의 그룹으로부터 선택됨을 특징으로 하는 효소 센서.
  17. 제8항에 있어서, 산화환원 기능층은 폴리(피롤), 폴리(티에닐렌)의 산화환원 기능을 갖는 물질의 그룹으로부터 선택됨을 특징으로 하는 효소 센서.
  18. 효소의 분자 식별 기능에 의하여 소정의 기질 농도를 측정하는 산소 센서에 있어서, 도전성 기체와, 이 도전성 기체의 표면을 덮고 산화환원 기능을 갖는 산화환원 기능층과, 이 산화환원 기능층의 표면을 덮고 소정의 이온에 감응하는 이온 감응층과, 이 이온 감응층의 표면을 덮고 상기 기질의 화학반응을 촉진하는 효소로써 된 효소층을 갖고, 상기 도전성 기체의 전위에 의하여 상기 기질의 농도를 측정함을 특징으로 하는 효소 센서.
  19. 제18항에 있어서, 효소는 글루코오즈 옥시다제로서, 글루코오즈의 농도를 측정함을 특징으로 하는 효소 센서.
  20. 제18항에 있어서, 효소는 우레아제로서, 요소의 농도를 측정함을 특징으로 하는 효소 센서.
  21. 제18항에 있어서, 효소는 우리카제로서, 요산의 농도를 측정함을 특징으로 하는 효소 센서.
  22. 제18항에 있어서, 효소는 콜레스테롤 옥시다제로서, 콜레스테롤의 농도를 측정함을 특징으로 하는 효소 센서.
  23. 제18항에 있어서, 효소는 가교제에 의하여 가교 구조로 되어 있음을 특징으로 하는 효소 센서.
  24. 제18항에 있어서, 도전성 기체는 그라파이트 구조의 탄소임을 특징으로 하는 효소 센서.
  25. 제18항에 있어서, 산화환원 기능층은 퀴논-하이드로 퀴논형의 산화환원 반응을 행하는 물질의 그룹으로부터 선택됨을 특징으로 하는 효소 센서.
  26. 제18항에 있어서, 산화환원 기능층은 아민-퀴노이드형의 산화환원 반응을 행하는 물질의 그룹으로부터 선택됨을 특징으로 하는 효소 센서.
  27. 제18항에 있어서, 산화환원 기능층은 폴리(피롤), 폴리(티에닐렌)의 산화환원 반응을 행하는 물질의 그룹으로부터 선택됨을 특징으로 하는 효소 센서.
  28. 효소의 분자 식별 기능에 의하여 소정의 기질 농도를 측정하는 효소 센서에 있어서, 도전성 기체와, 이 도전성 기체를 피복하는 산소 환원 기능을 갖는 산소 환원 촉매층과, 산소 환원 촉매층을 피복하는 효소를 함유하는 효소층을 갖고, 효소 반응에 의하여 소비되는 산소 농도를 산소 환원 전류에 의하여 측정함을 특징으로 하는 효소 센서.
  29. 제28항에 있어서, 산소 환원 촉매층은 코발트 프탈로시 아닌 착체, 코발트 폴필린 착체 등의 중합체막으로부터 선택됨을 특징으로 하는 효소 센서.
  30. 제28항에 있어서, 효소막은 전해 중합법에 의하여 산소환원 촉매층에 효소를 고정화함을 특징으로 하는 효소 센서.
  31. 제30항에 있어서, 효소는 글루코오즈 옥시다제로서, 글루코오즈의 농도를 측정함을 특징으로 하는 효소 센서.
  32. 제30항에 있어서, 효소는 우레아제로서, 요소의 농도를 측정함을 특징으로 하는 효소 센서.
  33. 제30항에 있어서, 효소는 우리카제로서, 요산의 농도를 측정함을 특징으로 하는 효소 센서.
  34. 제30항에 있어서, 효소는 콜레스테롤 옥시다제로서, 콜레스테롤의 농도를 측정함을 특징으로 하는 효소 센서.
  35. 제30항에 있어서, 효소는 가교제에 의하여 가교 구조로 되어 있음을 특징으로 하는 효소 센서.
  36. 제28항에 있어서, 도전성 기체는 카본 파이버, 그라파이트, 백금, 금 등으로부터 선택됨을 특징으로 하는 효소 센서.
  37. 효소의 분자 식별 기능에 의하여 소정의 기질 농도를 측정하는 효소 센서에 있어서, 효소를 함유하는 효소층과, 이 효소층을 피복하여 효소의 유출과 기질의 유입을 제어하는 효소 제어층을 갖는 것을 특징으로 하는 효소 센서.
  38. 제37항에 있어서, 효소막은 전해 중합법에 의하여 산소환원 촉매층에 효소를 고정화하였음을 특징으로 하는 효소 센서.
  39. 제38항에 있어서, 효소는 글루코오즈 옥시다제로서, 클루코오즈의 농도를 측정함을 특징으로 하는 효소 센서.
  40. 제38항에 있어서, 효소는 우레아제로서, 요소의 농도를 측정함을 특징으로 하는 효소 센서.
  41. 제38항에 있어서, 효소는 우리카제로서, 요산의 농도를 측정함을 특징으로 하는 효소 센서.
  42. 제38항에 있어서, 효소는 콜레스테롤 옥시다제로서, 콜레스테롤의 농도를 측정함을 특징으로 하는 효소 센서.
  43. 제38항에 있어서, 효소는 가교제에 의하여 가교 구조로 되어 있음을 특징으로 하는 효소 센서.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870006187A 1986-06-27 1987-06-18 효소센서 KR890004367B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61149753A JPS636451A (ja) 1986-06-27 1986-06-27 酵素センサ
JP149753 1986-06-27

Publications (2)

Publication Number Publication Date
KR880000596A true KR880000596A (ko) 1988-03-28
KR890004367B1 KR890004367B1 (ko) 1989-10-31

Family

ID=15481997

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870006187A KR890004367B1 (ko) 1986-06-27 1987-06-18 효소센서

Country Status (5)

Country Link
US (1) US4927516A (ko)
EP (1) EP0251915A3 (ko)
JP (1) JPS636451A (ko)
KR (1) KR890004367B1 (ko)
DK (1) DK328487A (ko)

Families Citing this family (230)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2672561B2 (ja) * 1988-01-29 1997-11-05 テルモ株式会社 膜被履センサ
US5128015A (en) * 1988-03-15 1992-07-07 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
USRE36268E (en) * 1988-03-15 1999-08-17 Boehringer Mannheim Corporation Method and apparatus for amperometric diagnostic analysis
DE3812442A1 (de) * 1988-04-14 1989-10-26 Fraunhofer Ges Forschung Einrichtung zur enzympraeparation
JPH01272957A (ja) * 1988-04-25 1989-10-31 Terumo Corp イオン感応膜、その製造方法及びイオンセンサ
DK532589A (da) * 1988-10-27 1990-04-30 Terumo Corp Referenceelektrode
US5213675A (en) * 1988-10-27 1993-05-25 Terumo Kabushiki Kaisha Reference electrode, ion sensor and method of manufacturing the same
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
US5205920A (en) * 1989-03-03 1993-04-27 Noboru Oyama Enzyme sensor and method of manufacturing the same
US5269891A (en) * 1989-03-09 1993-12-14 Novo Nordisk A/S Method and apparatus for determination of a constituent in a fluid
EP0399127A1 (en) * 1989-05-23 1990-11-28 Pharmacia ENI Diagnostics Inc. Homogeneous immunochemical method for determining haptens by means of ion selective electrodes
US5264104A (en) * 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
US5320725A (en) * 1989-08-02 1994-06-14 E. Heller & Company Electrode and method for the detection of hydrogen peroxide
US5264105A (en) * 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
DE4003194A1 (de) * 1990-02-03 1991-08-08 Boehringer Mannheim Gmbh Verfahren und sensorelektrodensystem zur elektrochemischen bestimmung eines analyts oder einer oxidoreduktase sowie verwendung hierfuer geeigneter verbindungen
US5250439A (en) * 1990-07-19 1993-10-05 Miles Inc. Use of conductive sensors in diagnostic assays
US5202261A (en) * 1990-07-19 1993-04-13 Miles Inc. Conductive sensors and their use in diagnostic assays
CA2050057A1 (en) 1991-03-04 1992-09-05 Adam Heller Interferant eliminating biosensors
US5262305A (en) * 1991-03-04 1993-11-16 E. Heller & Company Interferant eliminating biosensors
US5593852A (en) 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
US5658443A (en) * 1993-07-23 1997-08-19 Matsushita Electric Industrial Co., Ltd. Biosensor and method for producing the same
AUPM506894A0 (en) * 1994-04-14 1994-05-05 Memtec Limited Novel electrochemical cells
AUPN239395A0 (en) * 1995-04-12 1995-05-11 Memtec Limited Method of defining an electrode area
US6413410B1 (en) 1996-06-19 2002-07-02 Lifescan, Inc. Electrochemical cell
AUPN363995A0 (en) 1995-06-19 1995-07-13 Memtec Limited Electrochemical cell
ES2103197B1 (es) * 1995-08-04 1998-01-16 Univ Alcala Henares Pasta conductora, electrodos y sensores electroquimicos que comprenden dicha pasta conductora, y su metodo de preparacion.
US6521110B1 (en) 1995-11-16 2003-02-18 Lifescan, Inc. Electrochemical cell
US6638415B1 (en) 1995-11-16 2003-10-28 Lifescan, Inc. Antioxidant sensor
AUPN661995A0 (en) * 1995-11-16 1995-12-07 Memtec America Corporation Electrochemical cell 2
US6863801B2 (en) 1995-11-16 2005-03-08 Lifescan, Inc. Electrochemical cell
US5830341A (en) * 1996-01-23 1998-11-03 Gilmartin; Markas A. T. Electrodes and metallo isoindole ringed compounds
US5795453A (en) * 1996-01-23 1998-08-18 Gilmartin; Markas A. T. Electrodes and metallo isoindole ringed compounds
GB9622304D0 (en) * 1996-10-26 1996-12-18 Univ Manchester Sensor
CN1240027A (zh) * 1996-10-30 1999-12-29 莫克里诊断公司 被校准的分析物化验系统
US6632349B1 (en) 1996-11-15 2003-10-14 Lifescan, Inc. Hemoglobin sensor
SE9700384D0 (sv) * 1997-02-04 1997-02-04 Biacore Ab Analytical method and apparatus
AU6157898A (en) 1997-02-06 1998-08-26 E. Heller & Company Small volume (in vitro) analyte sensor
US7885697B2 (en) 2004-07-13 2011-02-08 Dexcom, Inc. Transcutaneous analyte sensor
US7657297B2 (en) 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
US9155496B2 (en) 1997-03-04 2015-10-13 Dexcom, Inc. Low oxygen in vivo analyte sensor
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US6073482A (en) * 1997-07-21 2000-06-13 Ysi Incorporated Fluid flow module
US5932799A (en) * 1997-07-21 1999-08-03 Ysi Incorporated Microfluidic analyzer module
US6293012B1 (en) 1997-07-21 2001-09-25 Ysi Incorporated Method of making a fluid flow module
AUPO855897A0 (en) 1997-08-13 1997-09-04 Usf Filtration And Separations Group Inc. Automatic analysing apparatus II
US6193865B1 (en) 1997-09-11 2001-02-27 Usf Filtration And Separations Group, Inc. Analytic cell
AU738325B2 (en) 1997-12-22 2001-09-13 Roche Diagnostics Operations Inc. Meter
US7494816B2 (en) 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
US8071384B2 (en) 1997-12-22 2011-12-06 Roche Diagnostics Operations, Inc. Control and calibration solutions and methods for their use
US7390667B2 (en) 1997-12-22 2008-06-24 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC phase angle measurements
US7407811B2 (en) 1997-12-22 2008-08-05 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC excitation
US6103033A (en) * 1998-03-04 2000-08-15 Therasense, Inc. Process for producing an electrochemical biosensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6878251B2 (en) 1998-03-12 2005-04-12 Lifescan, Inc. Heated electrochemical cell
US6652734B1 (en) 1999-03-16 2003-11-25 Lifescan, Inc. Sensor with improved shelf life
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
WO2000012512A1 (en) 1998-08-28 2000-03-09 Destiny Pharma Limited Porphyrin derivatives, their use in photodynamic therapy and medical devices containing them
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
USD433755S (en) * 1999-02-25 2000-11-14 Minimed Inc. Glucose sensor
EP1192269A2 (en) 1999-06-18 2002-04-03 Therasense, Inc. MASS TRANSPORT LIMITED i IN VIVO /i ANALYTE SENSOR
US20050103624A1 (en) 1999-10-04 2005-05-19 Bhullar Raghbir S. Biosensor and method of making
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
RU2278612C2 (ru) 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
US6444115B1 (en) 2000-07-14 2002-09-03 Lifescan, Inc. Electrochemical method for measuring chemical reaction rates
ES2167258B2 (es) * 2000-07-28 2003-03-01 Univ Madrid Complutense Biosensor amperometrico composito para la determinacion de colesterol en alimentos.
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6576102B1 (en) 2001-03-23 2003-06-10 Virotek, L.L.C. Electrochemical sensor and method thereof
US6572745B2 (en) * 2001-03-23 2003-06-03 Virotek, L.L.C. Electrochemical sensor and method thereof
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
IL156007A0 (en) 2001-10-10 2003-12-23 Lifescan Inc Electrochemical cell
US7018843B2 (en) * 2001-11-07 2006-03-28 Roche Diagnostics Operations, Inc. Instrument
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US20060134713A1 (en) 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US8771183B2 (en) 2004-02-17 2014-07-08 Abbott Diabetes Care Inc. Method and system for providing data communication in continuous glucose monitoring and management system
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
JP4619359B2 (ja) 2003-06-20 2011-01-26 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト フレア状に形成された試料受入チャンバーを持つ試験片
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
US8071030B2 (en) 2003-06-20 2011-12-06 Roche Diagnostics Operations, Inc. Test strip with flared sample receiving chamber
US8058077B2 (en) 2003-06-20 2011-11-15 Roche Diagnostics Operations, Inc. Method for coding information on a biosensor test strip
US7488601B2 (en) 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
US8206565B2 (en) 2003-06-20 2012-06-26 Roche Diagnostics Operation, Inc. System and method for coding information on a biosensor test strip
US7645373B2 (en) 2003-06-20 2010-01-12 Roche Diagnostic Operations, Inc. System and method for coding information on a biosensor test strip
US7604721B2 (en) 2003-06-20 2009-10-20 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US7645421B2 (en) 2003-06-20 2010-01-12 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7718439B2 (en) 2003-06-20 2010-05-18 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8282549B2 (en) 2003-12-09 2012-10-09 Dexcom, Inc. Signal processing for continuous analyte sensor
US20080119703A1 (en) 2006-10-04 2008-05-22 Mark Brister Analyte sensor
US9135402B2 (en) 2007-12-17 2015-09-15 Dexcom, Inc. Systems and methods for processing sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US8845536B2 (en) 2003-08-01 2014-09-30 Dexcom, Inc. Transcutaneous analyte sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US8060173B2 (en) 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US8886273B2 (en) 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
US8788006B2 (en) 2003-08-01 2014-07-22 Dexcom, Inc. System and methods for processing analyte sensor data
US7959569B2 (en) 2003-08-01 2011-06-14 Dexcom, Inc. System and methods for processing analyte sensor data
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US20050124060A1 (en) * 2003-10-20 2005-06-09 Masaki Yamaguchi Enzyme activity measuring apparatus, enzyme activity measuring method, sample transcription apparatus and color measuring apparatus
USD914881S1 (en) 2003-11-05 2021-03-30 Abbott Diabetes Care Inc. Analyte sensor electronic mount
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US20050121826A1 (en) * 2003-12-03 2005-06-09 Kiamars Hajizadeh Multi-sensor device for motorized meter and methods thereof
US8287453B2 (en) 2003-12-05 2012-10-16 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP1711790B1 (en) 2003-12-05 2010-09-08 DexCom, Inc. Calibration techniques for a continuous analyte sensor
US20050182451A1 (en) * 2004-01-12 2005-08-18 Adam Griffin Implantable device with improved radio frequency capabilities
US7637868B2 (en) 2004-01-12 2009-12-29 Dexcom, Inc. Composite material for implantable device
WO2005078118A1 (en) 2004-02-06 2005-08-25 Bayer Healthcare Llc Oxidizable species as an internal reference for biosensors and method of use
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US7556723B2 (en) 2004-06-18 2009-07-07 Roche Diagnostics Operations, Inc. Electrode design for biosensor
US7569126B2 (en) 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US20070045902A1 (en) 2004-07-13 2007-03-01 Brauker James H Analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US7640048B2 (en) 2004-07-13 2009-12-29 Dexcom, Inc. Analyte sensor
US7905833B2 (en) 2004-07-13 2011-03-15 Dexcom, Inc. Transcutaneous analyte sensor
ES2362790T3 (es) * 2004-09-02 2011-07-13 Abbott Point Of Care, Inc. Sensor de nitrógeno ureico en sangre (bun).
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US8613703B2 (en) 2007-05-31 2013-12-24 Abbott Diabetes Care Inc. Insertion devices and methods
US8571624B2 (en) 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
GB0509919D0 (en) * 2005-05-16 2005-06-22 Ralph Ellerker 1795 Ltd Improvements to door closure system
MX2008000836A (es) 2005-07-20 2008-03-26 Bayer Healthcare Llc Amperimetria regulada.
US7794778B2 (en) * 2005-08-26 2010-09-14 Chung Yuan Christian University Amperometric sensor for uric acid and method for the same
EP1934591B1 (en) 2005-09-30 2019-01-02 Ascensia Diabetes Care Holdings AG Gated voltammetry
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
EP1968432A4 (en) 2005-12-28 2009-10-21 Abbott Diabetes Care Inc INTRODUCTION OF A MEDICAL DEVICE
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US9757061B2 (en) 2006-01-17 2017-09-12 Dexcom, Inc. Low oxygen in vivo analyte sensor
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
EP1991110B1 (en) 2006-03-09 2018-11-07 DexCom, Inc. Systems and methods for processing analyte sensor data
US8529751B2 (en) 2006-03-31 2013-09-10 Lifescan, Inc. Systems and methods for discriminating control solution from a physiological sample
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
TW200738884A (en) * 2006-04-04 2007-10-16 Univ Nat Yunlin Sci & Tech Uricase enzyme biosensors and fabrication method thereof, sensing systems and sensing circuits comprising the same
US20080071157A1 (en) 2006-06-07 2008-03-20 Abbott Diabetes Care, Inc. Analyte monitoring system and method
GB0616566D0 (en) * 2006-08-19 2006-09-27 Rolls Royce Plc An alloy and method of treating titanium aluminide
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
EP2152350A4 (en) 2007-06-08 2013-03-27 Dexcom Inc INTEGRATED MEDICINE DELIVERY DEVICE FOR USE WITH A CONTINUOUS ANALYZING SUBSTANCE SENSOR
US8702932B2 (en) 2007-08-30 2014-04-22 Pepex Biomedical, Inc. Electrochemical sensor and method for manufacturing
WO2009051901A2 (en) * 2007-08-30 2009-04-23 Pepex Biomedical, Llc Electrochemical sensor and method for manufacturing
US8778168B2 (en) 2007-09-28 2014-07-15 Lifescan, Inc. Systems and methods of discriminating control solution from a physiological sample
EP4098177A1 (en) 2007-10-09 2022-12-07 DexCom, Inc. Integrated insulin delivery system with continuous glucose sensor
US8417312B2 (en) 2007-10-25 2013-04-09 Dexcom, Inc. Systems and methods for processing sensor data
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
US9839395B2 (en) 2007-12-17 2017-12-12 Dexcom, Inc. Systems and methods for processing sensor data
US8603768B2 (en) 2008-01-17 2013-12-10 Lifescan, Inc. System and method for measuring an analyte in a sample
WO2009105709A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8396528B2 (en) 2008-03-25 2013-03-12 Dexcom, Inc. Analyte sensor
US8551320B2 (en) 2008-06-09 2013-10-08 Lifescan, Inc. System and method for measuring an analyte in a sample
WO2010033724A2 (en) 2008-09-19 2010-03-25 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
WO2010056878A2 (en) 2008-11-14 2010-05-20 Pepex Biomedical, Llc Electrochemical sensor module
US8506740B2 (en) 2008-11-14 2013-08-13 Pepex Biomedical, Llc Manufacturing electrochemical sensor module
US8951377B2 (en) 2008-11-14 2015-02-10 Pepex Biomedical, Inc. Manufacturing electrochemical sensor module
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US20100198034A1 (en) 2009-02-03 2010-08-05 Abbott Diabetes Care Inc. Compact On-Body Physiological Monitoring Devices and Methods Thereof
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
EP2410910A4 (en) 2009-03-27 2014-10-15 Dexcom Inc METHODS AND SYSTEMS FOR PROMOTING GLUCOSE MANAGEMENT
WO2010127050A1 (en) 2009-04-28 2010-11-04 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
WO2011041469A1 (en) 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
EP4066731A1 (en) 2010-03-24 2022-10-05 Abbott Diabetes Care, Inc. Medical device inserters
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
WO2012142502A2 (en) 2011-04-15 2012-10-18 Dexcom Inc. Advanced analyte sensor calibration and error detection
US9504162B2 (en) 2011-05-20 2016-11-22 Pepex Biomedical, Inc. Manufacturing electrochemical sensor modules
CA2840640C (en) 2011-11-07 2020-03-24 Abbott Diabetes Care Inc. Analyte monitoring device and methods
FI4056105T3 (fi) 2011-12-11 2023-12-28 Abbott Diabetes Care Inc Analyyttisensorilaitteita
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
BR112015012958B1 (pt) 2012-12-03 2022-03-15 Pepex Biomedical, Inc Módulo sensor para detectar um analito em uma amostra de sangue
US8858884B2 (en) 2013-03-15 2014-10-14 American Sterilizer Company Coupled enzyme-based method for electronic monitoring of biological indicator
US9121050B2 (en) 2013-03-15 2015-09-01 American Sterilizer Company Non-enzyme based detection method for electronic monitoring of biological indicator
WO2015127354A1 (en) * 2014-02-24 2015-08-27 Siemens Healthcare Diagnostics Inc. Potentiometric sensor, kit and method of use
WO2015187959A1 (en) 2014-06-04 2015-12-10 Pepex Biomedical, Inc. Electrochemical sensors and methods for making electrochemical sensors using advanced printing technology
EP3294134B1 (en) 2015-05-14 2020-07-08 Abbott Diabetes Care Inc. Inserter system for a compact medical device and corresponding method
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
US11058328B2 (en) * 2015-12-31 2021-07-13 Banpil Photonics, Inc. System for screening and diagnosis of diabetes
US11071478B2 (en) 2017-01-23 2021-07-27 Abbott Diabetes Care Inc. Systems, devices and methods for analyte sensor insertion
US11943876B2 (en) 2017-10-24 2024-03-26 Dexcom, Inc. Pre-connected analyte sensors
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1442303A (en) * 1972-09-08 1976-07-14 Radiometer As Cell for electro-chemical analysis
DE2454610C2 (de) * 1973-11-28 1982-11-04 Conrad Zürich Sigg Einrichtung zum Verbrennen von schlammförmigen Abfallstoffen
US4321123A (en) * 1978-04-21 1982-03-23 Matsushita Electric Industrial Co., Ltd. Coenzyme immobilized electrode
US4340448A (en) * 1978-08-28 1982-07-20 University Of Pittsburgh Potentiometric detection of hydrogen peroxide and apparatus therefor
US4434229A (en) * 1979-05-21 1984-02-28 Matsushita Electric Industrial Co., Ltd. Enzyme immobilization with an immobilizing reagent in vapor phase
DE3127654C2 (de) * 1981-07-13 1983-05-11 Hoechst Ag, 6230 Frankfurt Automatisiertes Verfahren zur Selektion von Mikroorganismen
US4655880A (en) * 1983-08-01 1987-04-07 Case Western Reserve University Apparatus and method for sensing species, substances and substrates using oxidase
US4820399A (en) * 1984-08-31 1989-04-11 Shimadzu Corporation Enzyme electrodes
GB2168815A (en) * 1984-11-13 1986-06-25 Genetics Int Inc Bioelectrochemical assay electrode
JPS61213662A (ja) * 1985-03-19 1986-09-22 Terumo Corp pHセンサ−
US4671288A (en) * 1985-06-13 1987-06-09 The Regents Of The University Of California Electrochemical cell sensor for continuous short-term use in tissues and blood
US4680268A (en) * 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
GB8531755D0 (en) * 1985-12-24 1986-02-05 Genetics Int Inc Assay for cholestrol & derivatives
CA1254945A (en) * 1986-02-27 1989-05-30 Marco F. Cardosi Application of tetrathiafulvalenes in bioelectrochemical processes
JPS62240849A (ja) * 1986-04-11 1987-10-21 Omron Tateisi Electronics Co 酵素電極
US4704193A (en) * 1986-05-14 1987-11-03 Gte Laboratories Incorporated Covalently coupled cofactor modified electrodes and methods of synthesis and use
JPS63131057A (ja) * 1986-11-20 1988-06-03 Terumo Corp 酵素センサ

Also Published As

Publication number Publication date
US4927516A (en) 1990-05-22
EP0251915A3 (en) 1990-09-05
JPS636451A (ja) 1988-01-12
EP0251915A2 (en) 1988-01-07
JPH0419503B2 (ko) 1992-03-30
DK328487D0 (da) 1987-06-26
DK328487A (da) 1987-12-28
KR890004367B1 (ko) 1989-10-31

Similar Documents

Publication Publication Date Title
KR880000596A (ko) 효소 센서
US5312762A (en) Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte
Chaubey et al. Mediated biosensors
US5773270A (en) Three-layered membrane for use in an electrochemical sensor system
Ramanathan et al. Covalent immobilization of glucose oxidase to poly (O‐amino benzoic acid) for application to glucose biosensor
KR970001146B1 (ko) 가스측정용 바이오센서 및 그 제조방법
Shinohara et al. Enzyme microsensor for glucose with an electrochemically synthesized enzyme-polyaniline film
EP0585113B1 (en) Detecting an analyte in the gaseous or vapour phase by bioelectrochemical reactions and media therefor
US5202261A (en) Conductive sensors and their use in diagnostic assays
Silber et al. Poly (methylene blue)-modified thick-film gold electrodes for the electrocatalytic oxidation of NADH and their application in glucose biosensors
CA2163816C (en) Electrochemical enzyme biosensor
Jing-Juan et al. Amperometric glucose sensor based on coimmobilization of glucose oxidase and poly (p-phenylenediamine) at a platinum microdisk electrode
Xu et al. Amperometric glucose sensor based on glucose oxidase immobilized in electrochemically generated poly (ethacridine)
Kim et al. Disposable creatinine sensor based on thick-film hydrogen peroxide electrode system
JPS60113142A (ja) 重合体―触媒トランスデューサー
Palleschi et al. Ideal hydrogen peroxide-based glucose sensor
JPS61128152A (ja) 生物化学センサ
Dempsey et al. Electropolymerised o-phenylenediamine film as means of immobilising lactate oxidase for a L-lactate biosensor
JPH0136062B2 (ko)
Kuwabata et al. Preparation and properties of amperometric uric acid sensors
EP0467219A2 (en) Conductive sensors and their use in diagnostic assays
EP0304494A1 (en) Immobilization of biofunctional material, element prepared therefrom and measurement using the same
Buendía et al. Plasma‐treated polyethylene as electrochemical mediator for enzymatic glucose sensors: Toward bifunctional glucose and dopamine sensors
Bartlett et al. Electrochemical immobilization of enzymes. Part VI. Microelectrodes for the detection of L-lactate based on flavocytochrome b 2 immobilized in a poly (phenol) film
Shin et al. In situ biochemical reduction of interference in an amperometric biosensor with a novel heterobilayer configuration of polypyrrole/glucose oxidase/horseradish peroxidase

Legal Events

Date Code Title Description
A201 Request for examination
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20001025

Year of fee payment: 12

LAPS Lapse due to unpaid annual fee