KR870008581A - 안정하고 주사가능한 1,4-디히드록시-5,8-비스 [2-(2-히드록시에틸아미노)에틸아미노]안트라퀴논, 디히드로클로라이드의 약학적 배합제제 - Google Patents
안정하고 주사가능한 1,4-디히드록시-5,8-비스 [2-(2-히드록시에틸아미노)에틸아미노]안트라퀴논, 디히드로클로라이드의 약학적 배합제제 Download PDFInfo
- Publication number
- KR870008581A KR870008581A KR870002031A KR870002031A KR870008581A KR 870008581 A KR870008581 A KR 870008581A KR 870002031 A KR870002031 A KR 870002031A KR 870002031 A KR870002031 A KR 870002031A KR 870008581 A KR870008581 A KR 870008581A
- Authority
- KR
- South Korea
- Prior art keywords
- hydroxyethylamino
- dihydrochloride
- ethylamino
- anthraquinone
- dihydroxy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (3)
- 메타중아황산 나트륨 0.01~0.10%, EDTA이 나트륨 0.01~0.11% 및 글리신 0.05~0.20%를 함유한 pH2.0~3.5의 등장액내에 1,4-디히드록시-5,8-비스[2-(2-히드록시에틸아미노)에틸아미노]안트라퀴논, 디히드로클로라이드가 배합제제의 ml당 1~5mg으로 포함된 약제학적인 배합제제.
- 제 1 항에 있어서, 1,4-디히드록시-5,8-비스[2-(2-히드록시에틸아미노)에틸아미노]안트라퀴논, 디히드로클로라이드의 농도가 2mg/ml, 메타중아황산 나트륨의 농도가 0.05%, EDTA 이나트륨의 농도가 0.10% 및 글리신의 농도가 0.10%인 배합제제.
- 황산화제의 첨가, 특정 pH 범위의 조절 및 적절한 금속이온 킬레이트 화제의 첨가로 구성되는 정상적인 저장 조건하에서 안정한 배합제제의 제조방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83724386A | 1986-03-07 | 1986-03-07 | |
US06/837,243 | 1986-03-07 | ||
US837243 | 1986-03-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR870008581A true KR870008581A (ko) | 1987-10-19 |
KR900002030B1 KR900002030B1 (ko) | 1990-03-31 |
Family
ID=25273922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019870002031A KR900002030B1 (ko) | 1986-03-07 | 1987-03-06 | 안정하고 주사가능한 1,4-디히드록시-5,8-비스[2-(2-히드록시에틸아미노)에틸아미노]안트라퀴논, 디히드로클로라이드의 약학적 배합제제 |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0236822B1 (ko) |
JP (1) | JPH0717500B2 (ko) |
KR (1) | KR900002030B1 (ko) |
AT (1) | ATE59290T1 (ko) |
AU (1) | AU593330B2 (ko) |
CA (1) | CA1283607C (ko) |
DE (1) | DE3766984D1 (ko) |
DK (1) | DK166754B1 (ko) |
ES (1) | ES2033247T3 (ko) |
FI (1) | FI84977C (ko) |
GR (1) | GR3001503T3 (ko) |
HK (1) | HK63991A (ko) |
HU (1) | HU199286B (ko) |
IE (1) | IE60025B1 (ko) |
IL (1) | IL81681A (ko) |
NO (1) | NO173635C (ko) |
NZ (1) | NZ219454A (ko) |
PH (1) | PH22808A (ko) |
PT (1) | PT84398B (ko) |
SG (1) | SG45292G (ko) |
ZA (1) | ZA871652B (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE59409088D1 (de) * | 1994-10-04 | 2000-02-24 | Lohmann Rudolf Lomapharm | Lösungen von Anthrachinonen zur parenteralen Applikation |
DE19818802A1 (de) * | 1998-04-27 | 1999-10-28 | Dresden Arzneimittel | Stabile Mitoxantron-Lösungen |
TW200526268A (en) * | 2003-12-17 | 2005-08-16 | Takeda Pharmaceutical | Injectable composition |
KR20130132496A (ko) * | 2010-12-09 | 2013-12-04 | 마루이시세이야쿠가부시키가이샤 | 아세트아미노펜의 안정화제 |
CN114601791B (zh) * | 2020-12-08 | 2023-09-19 | 成都倍特药业股份有限公司 | 一种盐酸米托蒽醌液体制剂及其制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3230143A (en) * | 1965-05-14 | 1966-01-18 | Merck & Co Inc | Antihypertensive injection methods using acid addition salts of alkyl esters of alpha-methyl-3, 4-dihy-droxyphenylalanine |
US4223022A (en) * | 1978-01-16 | 1980-09-16 | Schering Corporation | Stabilized aminoglycoside antibiotic formulations |
US4328213A (en) * | 1979-11-28 | 1982-05-04 | Schering Corporation | Stable injectable labetalol formulation |
DE3574932D1 (de) * | 1984-02-27 | 1990-02-01 | American Cyanamid Co | Verwendung von 1,4 bisubstituierten anthrachinonen zur herstellung von immunsuppressiva. |
-
1987
- 1987-02-20 DE DE8787102448T patent/DE3766984D1/de not_active Expired - Lifetime
- 1987-02-20 EP EP87102448A patent/EP0236822B1/en not_active Expired - Lifetime
- 1987-02-20 ES ES198787102448T patent/ES2033247T3/es not_active Expired - Lifetime
- 1987-02-20 AT AT87102448T patent/ATE59290T1/de not_active IP Right Cessation
- 1987-02-26 IL IL81681A patent/IL81681A/xx not_active IP Right Cessation
- 1987-03-02 NZ NZ219454A patent/NZ219454A/en unknown
- 1987-03-04 PH PH34969A patent/PH22808A/en unknown
- 1987-03-04 PT PT84398A patent/PT84398B/pt unknown
- 1987-03-05 CA CA000531200A patent/CA1283607C/en not_active Expired - Lifetime
- 1987-03-06 HU HU87969A patent/HU199286B/hu not_active IP Right Cessation
- 1987-03-06 KR KR1019870002031A patent/KR900002030B1/ko not_active IP Right Cessation
- 1987-03-06 AU AU69773/87A patent/AU593330B2/en not_active Expired
- 1987-03-06 DK DK116687A patent/DK166754B1/da not_active IP Right Cessation
- 1987-03-06 FI FI870994A patent/FI84977C/fi not_active IP Right Cessation
- 1987-03-06 NO NO870950A patent/NO173635C/no unknown
- 1987-03-06 ZA ZA871652A patent/ZA871652B/xx unknown
- 1987-03-06 JP JP62050398A patent/JPH0717500B2/ja not_active Expired - Lifetime
- 1987-03-06 IE IE56987A patent/IE60025B1/en not_active IP Right Cessation
-
1991
- 1991-02-26 GR GR90400362T patent/GR3001503T3/el not_active IP Right Cessation
- 1991-08-15 HK HK639/91A patent/HK63991A/xx not_active IP Right Cessation
-
1992
- 1992-04-24 SG SG45292A patent/SG45292G/en unknown
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Payment date: 20050114 Year of fee payment: 16 |
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