KR870006411A - 면역 분석용 시약지의 제조방법 - Google Patents

면역 분석용 시약지의 제조방법 Download PDF

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KR870006411A
KR870006411A KR860010552A KR860010552A KR870006411A KR 870006411 A KR870006411 A KR 870006411A KR 860010552 A KR860010552 A KR 860010552A KR 860010552 A KR860010552 A KR 860010552A KR 870006411 A KR870006411 A KR 870006411A
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cellulose
fiber
acid
synthetic fiber
fleece
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KR890002942B1 (ko
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바이에르 만프레드
피터 카스파 클라우스
섀페르 타이너
트래거 울리히
뇌트젤 쉬그프리드
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독토르, 포우쿠에르
뵈링거 만하임 게엠베하
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
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  • Hematology (AREA)
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  • Urology & Nephrology (AREA)
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  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
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  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
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  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of Radiation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
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  • Compositions Of Macromolecular Compounds (AREA)

Abstract

내용 없음.

Description

면역 분석용 시약지의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (28)

  1. 셀룰로우스/합성 섬유 1-90/99-10의 중량비인 셀룰로우스/합성 섬유 혼합물의 섬유 플리스를 과요오드산염으로 처리하여 활성시키고, 활성화된 섬유 플리스를 산으로 처리된 단백질로 중량하고, 비결합 단백질을 제거하는 것으로 구성된, 면역분석용 시약지의 제조방법.
  2. 제1항에 있어서, 셀룰로우스/합성 섬유의 중량비가 10-80/20-90인 방법.
  3. 제2항에 있어서, 셀룰로우스/합성 섬유의 중량비가 20-40/60-80인 방법.
  4. 전기한 항의 어느 한 항에 있어서, 셀룰로우스 성분이 셀룰로우스, 셀룰로우스 아황산염, 셀룰로우스 황산염 및/또는 린터(linter)인 방법.
  5. 전기한 항의 어느 한 항에 있어서, 합성 섬유물질이 폴리아미드, 폴리아크릴로니트릴, 재생 셀룰로우스, 유리 섬유 또는 폴리에스테르인 방법.
  6. 전기한 항의 어느 한 항에 있어서, 합성 섬유에 부가하여, 셀룰로우스 섬유 중량의 0.1-30중량%로 결합 섬유 및/또는 습윤제가 사용되는 방법.
  7. 제6항에 있어서, 결합 섬유로서 폴리비닐 알콜, 폴리우레탄, 폴리스티렌 및/또는 폴리비닐 클로라이드가 사용되는 방법.
  8. 제7항 또는 제8항에 있어서, 습윤제로서 폴리아미드-에피클로로히드린, 오소-포름알데하이드 및/또는 멜라민-포름알데하이드가 사용되는 방법.
  9. 전기한 항의 어느 한 항에 있어서, 과요오드산염과 섬유의 활성화가 플리스 형성 전에 행해지는 방법.
  10. 제9항에 있어서, 셀룰로우스산 과요오드산염과 처리하는 방법.
  11. 전기한 양의 어느 한 항에 있어서, 단백질의 산 선처리가 그것 자체에서 행해지는 방법.
  12. 전기한 항의 어느 한 항에 있어서, 항체가 단백질로서 사용되는 방법.
  13. 제12항에 있어서, 항체가 산 용액에 대해 투석되고, 얻은 항체 용액은 동결하고, 섬유 플리스는 pH6-7에서 수용액내의 처리된 항체로 침투시키는 방법.
  14. 제13항에 있어서, 사용된 산이 락트산, 말레인산, 염산, 프로피온산, 아세트산 또는 타르타르산인 방법.
  15. 제12항에 있어서, 섬유 플리스의 중량을 위해, 항체를 pH2-4의 산 용액에 넣고 섬유 플리스를 이 용액으로 침투시키는 방법.
  16. 전기한 항의 어느 한 항에 있어서, 비결합 단백질을 pH6-8의 수성 완충 용액으로 증량된 플리스를 세척함에 의해 제거하는 방법.
  17. 제1항에서 제16항까지의 방법으로 제조된, 면역 분석용 시약지.
  18. 이질 면역 분석의 시약 담체로서, 셀룰로우스/합성 섬유 중량비 90-l/1O-99인 셀룰로우스/합성 섬유 혼합물의 섬유 플리스 사용법.
  19. 제18항에 있어서, 셀룰로우스/합성 섬유의 중량비가 10-80/20-90인 사용법.
  20. 제19항에 있어서, 셀룰로우스/합성 섬유의 중량비가 20-40/60-80인 사용법.
  21. 제18항에서 제20항까지의 어느 한 항에 있어서, 셀룰로우스 성분이 셀룰로우스, 셀룰로우스 아황산 염, 셀룰로우스 황산염 및/또는 린터인 사용법.
  22. 제18항에서 제21항까지의 어느 한 항에 있어서, 합성 섬유 물질이 폴리아미드, 재생 셀룰로우스, 폴리아크릴로니트릴, 유리 섬유 및/또는 폴리에스테르인 사용법.
  23. 제18항에서 제22항까지의 어느 한 항에 있어서, 합성 섬유에 부가하여, 결합 섬유 및/또는 습윤제가 셀룰로우스 섬유 중량의 0.1-30중량%로 존재하는 사용법.
  24. 제23항에 있어서, 결합 섬유로서 폴리비닐 알콜, 폴리우레탄, 폴리스티렌 및/또는 폴리비닐 클로라이드가 사용되는 사용법.
  25. 제23항 또는 제24항에 있어서, 습윤제가 폴리아미드-에피클로로히드린, 요소-포름알데하이드 및/또는 멜라민-포름알데하이드가 사용되는 사용법.
  26. 셀로우스/룰합 성섬 1-90/99-10유중량비인 셀룰로우스/합성 섬유 혼합물의 섬유플리스로 구성되는, 멈역 분석용 시약.
  27. 제26항에 있어서, 과요오드 산염으로 활성화된 섬유 플리스로 구성되는 시약지.
  28. 제26항 또는 제27항에 있어서, 산으로 선처리된 단백질로 증량된 섬유 플리스로 구성되는 시약지.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860010552A 1985-12-11 1986-12-10 면역분석용 시약지의 제조 방법 KR890002942B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3543749.9 1985-12-11
DEP3543749.9 1985-12-11
DE19853543749 DE3543749A1 (de) 1985-12-11 1985-12-11 Verfahren zur herstellung eines reagenzpapieres fuer die immunologische analyse

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KR870006411A true KR870006411A (ko) 1987-07-11
KR890002942B1 KR890002942B1 (ko) 1989-08-12

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US (1) US4803171A (ko)
EP (1) EP0226182B1 (ko)
JP (1) JPH0614050B2 (ko)
KR (1) KR890002942B1 (ko)
AT (1) ATE63001T1 (ko)
DE (2) DE3543749A1 (ko)
ES (1) ES2022109B3 (ko)
FI (1) FI865022A (ko)

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DE3735684A1 (de) * 1987-10-22 1989-05-03 Boehringer Mannheim Gmbh Immunreaktives traegermaterial und verfahren zu seiner herstellung
DE3802366A1 (de) * 1988-01-27 1989-08-10 Boehringer Mannheim Gmbh Traegervlies fuer abloesbar impraegnierte reagenzien
US5217874A (en) 1989-04-04 1993-06-08 Helena Laboratories Corporation Fecal occult blood test product with positive and negative controls
US5196167A (en) 1989-04-04 1993-03-23 Helena Laboratories Corporation Fecal occult blood test product with positive and negative controls
JPH02296152A (ja) * 1989-05-11 1990-12-06 Hidenobu Akutsu 病状示唆検知用紙
FI90800C (fi) * 1991-03-13 1994-03-25 Veikko Naentoe Biospesifinen määritysmenetelmä sekä tuote määritystä varten
DE4123324C2 (de) * 1991-07-14 1996-01-11 Risa Ges Fuer Chemische Tech U Scheibe für Probenröhrchen und deren Verwendung
DE4211108A1 (de) * 1992-04-03 1993-10-07 Boehringer Mannheim Gmbh Viruslösung zum Einsatz bei Immunoassays
DE4236189A1 (de) * 1992-10-27 1994-04-28 Boehringer Mannheim Gmbh Verfahren zur simultanen Bestimmung von Antigenen und Antikörpern
US5561045A (en) * 1994-01-04 1996-10-01 Intracel Corporation Detection reagent, article, and immunoassay method
US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
US5580790A (en) * 1994-10-21 1996-12-03 Chiron Corporation Method and apparatus for processing fluids
US6274041B1 (en) 1998-12-18 2001-08-14 Kimberly-Clark Worldwide, Inc. Integrated filter combining physical adsorption and electrokinetic adsorption
US6537614B1 (en) 1998-12-18 2003-03-25 Kimberly-Clark Worldwide, Inc. Cationically charged coating on hydrophobic polymer fibers with poly (vinyl alcohol) assist
US6645388B2 (en) 1999-12-22 2003-11-11 Kimberly-Clark Corporation Leukocyte depletion filter media, filter produced therefrom, method of making same and method of using same
US6927062B2 (en) * 2002-11-25 2005-08-09 Agdia, Inc. Controls and standards for assays and method for manufacture thereof
ITMI20031483A1 (it) * 2003-07-21 2005-01-22 Bartholdy Consultadoria E Servicos Lda Fibre marcate e metodi immunochimici per la loro rivelazione
US7248356B2 (en) * 2004-04-06 2007-07-24 Pulsion Medical Systems Ag Calibration aid
JP5573932B2 (ja) 2012-12-14 2014-08-20 株式会社豊田自動織機 電池パック

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DE2158124C3 (de) * 1971-11-24 1975-03-13 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von Polyamidvlies oder -filz als saugfähiger Träger für diagnostische Mittel
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
FR2502786B1 (fr) * 1981-03-24 1985-06-21 Stallergenes Laboratoire Procede de fixation d'antigenes et d'anticorps sur support de polysaccharides, et utilisation du produit ainsi obtenu pour les dosages immunologiques
JPS5899966A (ja) * 1981-11-30 1983-06-14 コ−ディス、コ−ポレイション 治療的免疫除去装置および方法
JPS5977356A (ja) * 1982-06-30 1984-05-02 Fuji Photo Film Co Ltd 螢光アツセイ用多層分析要素およびそれを用いる螢光アツセイ法
US4444880A (en) * 1982-07-27 1984-04-24 Syva Company Periodate removal of ascorbate interference in dipsticks for immunoassays
JPS60222769A (ja) * 1984-04-19 1985-11-07 Fuji Photo Film Co Ltd 一体型多層分析要素

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Publication number Publication date
FI865022A (fi) 1987-06-12
DE3543749A1 (de) 1987-06-19
EP0226182A1 (de) 1987-06-24
JPS62138761A (ja) 1987-06-22
ES2022109B3 (es) 1991-12-01
JPH0614050B2 (ja) 1994-02-23
ATE63001T1 (de) 1991-05-15
KR890002942B1 (ko) 1989-08-12
FI865022A0 (fi) 1986-12-10
US4803171A (en) 1989-02-07
EP0226182B1 (de) 1991-04-24
DE3678912D1 (de) 1991-05-29

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