KR850008450A - 수포의 안정화 방법 - Google Patents
수포의 안정화 방법 Download PDFInfo
- Publication number
- KR850008450A KR850008450A KR1019850003629A KR850003629A KR850008450A KR 850008450 A KR850008450 A KR 850008450A KR 1019850003629 A KR1019850003629 A KR 1019850003629A KR 850003629 A KR850003629 A KR 850003629A KR 850008450 A KR850008450 A KR 850008450A
- Authority
- KR
- South Korea
- Prior art keywords
- micelle
- gel matrix
- polymerizable
- polymerizable gel
- protective
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
- A61K51/1227—Micelles, e.g. phospholipidic or polymeric micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
- A61K51/1234—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Dispersion Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Colloid Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Luminescent Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Ceramic Products (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Signal Processing For Digital Recording And Reproducing (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
내용없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
본 발명 방법에 의한 수포의 안정화도를 도시한 도면.
Claims (18)
- 액체로 변화되어 보호 갤 표면을 현탁수용액으로 변화시킬 수 있는 중합성 겔 매트릭스에 미셀입자를 현탁시켜 그 미셀입자 주위에 보호 겔 표면을 형성시키는 것을 특징으로 하는 미셀입자의 안정화 및 수명증대 방법.
- 제1항에 있어서, 상기 중합성 겔 매트릭스가 거의 실온 또는 그 이상의 온동에서 용융하여 상기 보호 겔 표면을 수용액으로 변화시킬 수 있는 다당류 또는 폴리펩티드인 방법.
- 제2항에 있어서, 상기 중합성 겔 매트릭스가 젤라틴인 방법.
- 제2항에 있어서, 상기 중합성 겔 매트릭스가 아가로우즈인 방법.
- 제1항 또는 제2항에 있어서, 상기 미셀입자가 인지질인 방법.
- 제5항에 있어서, 상기 수포의 내부에 치료제를 포함시키는 방법.
- 제1항, 제2항 또는 제5항에 있어서, 상기 중합성 겔 매트릭스 약 0.5중량% 내지 약 10중량%의 겔을 함유하는 방법.
- 제7항에 있어서, 상기 중합성 겔 매트릭스가 약 1중량% 내지 약 5중량%의 겔을 함유하는 방법.
- 제1항,제2항 또는 제5항에 있어서, 상기 중합성 겔 매트릭스를 액체로 변화시킴으로써 그 갤 매트릭스는 현탁수용액으로 변화시키고, 이어서 미셀입자에는 방사성 핵종으로 표지를 붙이는 방법.
- 액체로 변화되어 보호 겔 표면을 현탁수용액으로 변화시킬 수 있는 중합성 겔 매트릭스에 미셀입자를 현탁시켜 그 미셀입자 주위에 보호 겔 표면이 형성된 미셀입자.
- 제10항에 있어서, 상기 중합성 겔 매트릭스가 거의 실온 또는 그 이상의 온도에서 용융하여 상기 보호겔 표면을 수용액으로 변화시킬 수 있는 다당류 또는 폴리펩티드인 미셀입자.
- 제11항에 있어서, 상기 중합성 겔 매트릭스가 젤라틴인 미셀입자.
- 제11항에 있어서, 상기 중합성 겔 매트릭스가 아가로우즈인 미셀입자.
- 제11항에 있어서, 상기 미셀입자가 인지질인 미셀입자.
- 제14항에 있어서, 상기 수포의 내부에 치료제를 포함시키는 미셀입자.
- 제10항, 제11항 또는 제14항에 있어서, 상기 중합성 겔 매트릭스 약 0.5중량% 내지 약 10중량%의 겔을 함유하는 미셀입자.
- 제16항에 있어서, 상기 중합성 겔 매트릭스가 약 1중량% 내지 약 5중량%의 겔을 함유하는 미셀입자.
- 제10항, 제11항 또는 제14항에 있어서, 상기 중합성 겔 매트릭스는 현탁수용액으로 변화되어 있고, 미셀입자에는 방사성 핵종으로 표지를 붙인 미셀입자.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61425584A | 1984-05-25 | 1984-05-25 | |
US614255 | 1984-05-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR850008450A true KR850008450A (ko) | 1985-12-18 |
Family
ID=24460474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019850003629A KR850008450A (ko) | 1984-05-25 | 1985-05-25 | 수포의 안정화 방법 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0162724B1 (ko) |
JP (1) | JPH0696515B2 (ko) |
KR (1) | KR850008450A (ko) |
AT (1) | ATE93387T1 (ko) |
AU (1) | AU576363B2 (ko) |
CA (1) | CA1263311A (ko) |
DE (1) | DE3587541T2 (ko) |
DK (1) | DK164483C (ko) |
ES (1) | ES8608862A1 (ko) |
HU (1) | HU200698B (ko) |
IE (1) | IE61706B1 (ko) |
IL (1) | IL75315A (ko) |
ZA (1) | ZA853943B (ko) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4708861A (en) * | 1984-02-15 | 1987-11-24 | The Liposome Company, Inc. | Liposome-gel compositions |
US4740375A (en) * | 1985-02-25 | 1988-04-26 | Technology Unlimited, Inc. | Gelcores |
EP0199362A3 (en) * | 1985-04-26 | 1987-10-07 | Massachusetts Institute Of Technology | System and apparatus for delayed and pulsed release of biologically active substances |
GB8522963D0 (en) * | 1985-09-17 | 1985-10-23 | Biocompatibles Ltd | Microcapsules |
US4839111A (en) * | 1987-02-02 | 1989-06-13 | The University Of Tennessee Research Corporation | Preparation of solid core liposomes |
FR2620333B1 (fr) * | 1987-09-15 | 1990-01-05 | Inst Nat Sante Rech Med | Liposomes, leur procede de preparation et application desdits liposomes comme vecteur de produits |
US5006473A (en) * | 1988-08-09 | 1991-04-09 | Abbott Laboratories | Electrophoresis method using vesicles |
US5064655A (en) * | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
NZ313769A (en) * | 1995-08-10 | 2000-02-28 | Kazunori Kataoka | block polymer having a functional group presented on each end |
US5962015A (en) * | 1997-05-02 | 1999-10-05 | Kobo Products S.A.R.L. | Stabilized liposomes |
FR2764507B1 (fr) * | 1997-06-11 | 2000-10-20 | Lipogel Sarl | Compositions pulverulentes de liposomes unilamellaires, leur procede de preparation et leurs applications comme complements nutritionnels et comme complements nutritionnels et comme medicaments |
US6048546A (en) * | 1997-07-31 | 2000-04-11 | Sandia Corporation | Immobilized lipid-bilayer materials |
WO2000076476A1 (en) * | 1999-06-11 | 2000-12-21 | Endorex Corporation | Adjuvant-containing polymerized liposomes for oral, mucosal or intranasal vaccination |
US20050129751A1 (en) * | 2003-12-16 | 2005-06-16 | Rothenberg Barry E. | Drug delivery compositions and methods |
EP2066310B1 (de) | 2006-09-22 | 2012-04-18 | Mivital AG | Emulsionen enthaltend gummi arabicum |
US20110020428A1 (en) * | 2007-11-15 | 2011-01-27 | Qun Zeng | Gel-stabilized liposome compositions, methods for their preparation and uses thereof |
CN105532922A (zh) * | 2008-11-14 | 2016-05-04 | 阿彻丹尼尔斯米德兰德公司 | 有机凝胶组合物及其生产方法 |
FR2943252B1 (fr) * | 2009-03-17 | 2011-08-05 | Dermo Cosmetique Animale Lab De | Composition dermo-cosmetique |
BR112012029040A2 (pt) | 2010-05-14 | 2016-08-02 | Archer Daniels Midland Co | composição de organogel de fosfolipideo estruturado termorreversível comestível para uso em produto alimentício, método de estruturar uma fase orgânica comestível, produto ou ingrediente alimentício, composição, método de carregar um organogel de fosfolipídeo estruturado termorreversível comestível, método de revestir um alimento e composição de organogel de fosfolipídeo estruturado termorreversivel comestível para uso em um produto alimentício |
JP2012102043A (ja) * | 2010-11-10 | 2012-05-31 | Konica Minolta Holdings Inc | 単胞リポソームの製造方法、単胞リポソームの分散液とその乾燥粉末及びそれらの製造方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE18353T1 (de) * | 1981-07-02 | 1986-03-15 | Hoffmann La Roche | Verfahren zur herstellung von liposomenloesungen. |
GB2135647A (en) * | 1983-02-15 | 1984-09-05 | Squibb & Sons Inc | Method of preparing liposomes and products produced thereby |
US4608278A (en) * | 1983-06-22 | 1986-08-26 | The Ohio State University Research Foundation | Small particule formation and encapsulation |
FR2548902B1 (fr) * | 1983-07-13 | 1986-04-11 | Guerbet Sa | Gel pour embolisation therapeutique |
US4708861A (en) * | 1984-02-15 | 1987-11-24 | The Liposome Company, Inc. | Liposome-gel compositions |
-
1985
- 1985-05-24 CA CA000482261A patent/CA1263311A/en not_active Expired
- 1985-05-24 JP JP60111974A patent/JPH0696515B2/ja not_active Expired - Lifetime
- 1985-05-24 AU AU42856/85A patent/AU576363B2/en not_active Ceased
- 1985-05-24 DE DE85303676T patent/DE3587541T2/de not_active Expired - Fee Related
- 1985-05-24 AT AT85303676T patent/ATE93387T1/de active
- 1985-05-24 EP EP85303676A patent/EP0162724B1/en not_active Expired - Lifetime
- 1985-05-24 IL IL75315A patent/IL75315A/xx not_active IP Right Cessation
- 1985-05-24 ZA ZA853943A patent/ZA853943B/xx unknown
- 1985-05-24 IE IE130685A patent/IE61706B1/en not_active IP Right Cessation
- 1985-05-24 DK DK234185A patent/DK164483C/da active
- 1985-05-24 HU HU851987A patent/HU200698B/hu not_active IP Right Cessation
- 1985-05-24 ES ES543495A patent/ES8608862A1/es not_active Expired
- 1985-05-25 KR KR1019850003629A patent/KR850008450A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES8608862A1 (es) | 1986-09-01 |
HUT38266A (en) | 1986-05-28 |
IE851306L (en) | 1985-11-25 |
HU200698B (en) | 1990-08-28 |
IL75315A (en) | 1991-07-18 |
DK164483C (da) | 1992-11-16 |
JPH0696515B2 (ja) | 1994-11-30 |
AU576363B2 (en) | 1988-08-25 |
EP0162724A3 (en) | 1986-07-23 |
AU4285685A (en) | 1985-12-12 |
ATE93387T1 (de) | 1993-09-15 |
JPS60258109A (ja) | 1985-12-20 |
ZA853943B (en) | 1988-12-28 |
IE61706B1 (en) | 1994-11-30 |
EP0162724B1 (en) | 1993-08-25 |
DK234185A (da) | 1985-11-26 |
IL75315A0 (en) | 1985-09-29 |
DE3587541T2 (de) | 1993-12-23 |
DK164483B (da) | 1992-07-06 |
ES543495A0 (es) | 1986-09-01 |
DE3587541D1 (de) | 1993-09-30 |
DK234185D0 (da) | 1985-05-24 |
CA1263311A (en) | 1989-11-28 |
EP0162724A2 (en) | 1985-11-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR850008450A (ko) | 수포의 안정화 방법 | |
Ohkubo et al. | Rat liver alkaline phosphatase: Purification and properties | |
BR9712377A (pt) | Monitor eletroforético, e, sistema de exibição não emissivo. | |
BR8606835A (pt) | Capsulas de gelatina e processo para a sua obtencao | |
DE69435104D1 (de) | Herstellung von Weichgelatinekapseln | |
FI832314L (fi) | Friktionsreduktion genom anvaendning av ett viskoelastiskt ytaktivt medel | |
FI844597A0 (fi) | Foerfarande foer framstaellning av en synnerligen ren hyaluronsyra. | |
ES2052495T3 (es) | Terapia de fluidos con aniones l-lactato y/o piruvato. | |
IT8022479A0 (it) | Composizione vulcanizzabile di organopolisilossano contenente microcapsule. | |
IT1170993B (it) | Composizione anti-traspirante contenente come agenti attivi antitraspiranti cloruri d'alluminio ed ossicloruro di alluminio zirconio e relativo metodo di impiego | |
KR850000978A (ko) | 데포우 소염제의 제조방법 | |
MX156546A (es) | Composicion liquida acuosa estable de colorantes reactivos que contienen grupos beta-sulfatoetilsulfonilo | |
KR880013557A (ko) | 신규 안과용 조성물 | |
EP0659581A3 (en) | Stabilized materials for thermal bleaching of dyes. | |
Jasaitis et al. | Anilinonaphthalene sulfonate and other synthetic ions as mitochondrial membrane penetrants: An H+ pulse technique study | |
SE7700155L (sv) | Dispersion eller suspension av fast fas i flytande fas | |
IT1152475B (it) | Procedimento per porre a contatto gas e liquido e riempitivo per l'applicazione di tale procedimento | |
GB1303761A (ko) | ||
IT1189325B (it) | Preparazioni stabili di coloranti dispersi | |
ATE53006T1 (de) | Augenselektive betablockierende und diese enthaltende zusammensetzungen. | |
DK567582A (da) | Natriumchloridpraeparat i partikelform | |
JPS6437547A (en) | Direct positive silver halide photographic sensitive material having improved shelf stability | |
Omenyi et al. | Stability of erythrocyte suspensions layered on stationary and flowing liquids | |
MIKHO et al. | On the effect of energy dissipation on the drift of a horizontal pendulum(Effect of energy dissipation on drift of horizontal pendulum on vibrating base with application to gyroscopic suspension systems) | |
BR9814456A (pt) | Mostrador eletroforético encapsulado e processo para criar um mostrador eletroforético encapsulado |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application |