KR850000978A - 데포우 소염제의 제조방법 - Google Patents

데포우 소염제의 제조방법 Download PDF

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Publication number
KR850000978A
KR850000978A KR1019840003850A KR840003850A KR850000978A KR 850000978 A KR850000978 A KR 850000978A KR 1019840003850 A KR1019840003850 A KR 1019840003850A KR 840003850 A KR840003850 A KR 840003850A KR 850000978 A KR850000978 A KR 850000978A
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KR
South Korea
Prior art keywords
oil
formula
amides
esters
salts
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Application number
KR1019840003850A
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English (en)
Inventor
한스-디터델, (외 3)
Original Assignee
게르트 바디케, 하이레딘 야코비
트로폰 베르케 지엠비에이치 앤드 캄파니, 케이지
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Application filed by 게르트 바디케, 하이레딘 야코비, 트로폰 베르케 지엠비에이치 앤드 캄파니, 케이지 filed Critical 게르트 바디케, 하이레딘 야코비
Publication of KR850000978A publication Critical patent/KR850000978A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

내용 없음

Description

데포우 소염제의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 일반식(Ⅰ)의 화합물 및 이의 에스테르, 아미드 또는 염을, 비스콜레오, 이소프로필 미리스테이트, 에틸올레이트, 아주까리 기름, 참기름, 땅콩기름, 목화씨기름, 아먼드기름, 올리브유, 우각유, 중성오일 및 옥수수기름 중의 하나 이상을 함유하는 현탁제와 잘 혼합하고, 그 혼합물을 용기에 충진시킴을 특징으로 하여 일반식(Ⅰ)의 화합물 및 이의 에스테르, 아미드 또는 염, 및 현탁매질을 함유하는 데포우 제제를 제조하는 방법.
    상기 식에서,
    R은 수소, 저급알킬 또는 치환된 알킬이고,
    Ar은 아릴, 헤테로아릴, 치환된 아릴 또는 치환된 헤테로아릴이고,
    m 및/또는 n은 0일수 있으며, m+n은 1 또는 2이고,
    P는 0 또는 1이다.
  2. 제1항에 있어서, 일반식(Ⅰ)의 화합물 및 이의 에스테르, 아미드 또는 염이 3 내지 80중량%, 현탁제가 10 내지 70중량%인 방법.
    ※참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840003850A 1983-07-05 1984-07-04 데포우 소염제의 제조방법 KR850000978A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3324193,7 1983-07-05
DE19833324193 DE3324193A1 (de) 1983-07-05 1983-07-05 Depot-antiphlogistika

Publications (1)

Publication Number Publication Date
KR850000978A true KR850000978A (ko) 1985-03-14

Family

ID=6203193

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840003850A KR850000978A (ko) 1983-07-05 1984-07-04 데포우 소염제의 제조방법

Country Status (8)

Country Link
US (1) US4614741A (ko)
EP (1) EP0130514A3 (ko)
JP (1) JPS6036409A (ko)
KR (1) KR850000978A (ko)
DE (1) DE3324193A1 (ko)
DK (1) DK328484A (ko)
GR (1) GR82238B (ko)
PT (1) PT78838B (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH673395A5 (ko) * 1987-01-30 1990-03-15 Ciba Geigy Ag
US5283067A (en) * 1987-01-30 1994-02-01 Ciba-Geigy Corporation Parenteral suspensions
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
IT1318654B1 (it) * 2000-07-28 2003-08-27 Prodotti Antibiotici Spa Composizioni farmaceutiche comprendenti agenti antiinfiammatori e lorousi.
DE10059020A1 (de) * 2000-11-28 2002-05-29 Gruenenthal Gmbh Parenteral applizierbare Darreichungsformen
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
FR3000392B1 (fr) * 2012-12-27 2015-03-27 Virbac Nouvelles compositions pharmaceutiques veterinaires et leur procede de preparation
US20140187635A1 (en) 2012-12-28 2014-07-03 Themis Medicare Limited Diclofenac compositions
CA2931858C (en) * 2013-12-16 2018-12-11 Richard Andrew Ewin Long-acting ketoprofen compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1090703B (it) * 1976-12-03 1985-06-26 Scherer Ltd R P Perfezionamento nelle composizioni utili quali veicolo per farmaci
NL175882C (nl) * 1977-03-28 Procter & Gamble Farmaceutisch preparaat, dat een verbinding met ontstekingtegengaande werking bevat.
US4325949A (en) 1980-02-15 1982-04-20 American Cyanamid Company Combinations of agents which give enhanced anti-inflammatory activity
DE3026402A1 (de) * 1980-07-11 1982-02-04 Syntex Corp., Palo Alto, Calif. Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen
JPS5859912A (ja) * 1981-10-06 1983-04-09 Green Cross Corp:The 鎮痛消炎物質脂肪乳剤

Also Published As

Publication number Publication date
EP0130514A3 (de) 1986-08-13
GR82238B (ko) 1984-12-13
US4614741A (en) 1986-09-30
PT78838A (en) 1984-08-01
PT78838B (en) 1986-06-02
DK328484A (da) 1985-01-06
EP0130514A2 (de) 1985-01-09
DE3324193A1 (de) 1985-01-17
DK328484D0 (da) 1984-07-04
JPS6036409A (ja) 1985-02-25

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