KR840005111A - 복소환식 화합물 - Google Patents

복소환식 화합물 Download PDF

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Publication number
KR840005111A
KR840005111A KR1019830002511A KR830002511A KR840005111A KR 840005111 A KR840005111 A KR 840005111A KR 1019830002511 A KR1019830002511 A KR 1019830002511A KR 830002511 A KR830002511 A KR 830002511A KR 840005111 A KR840005111 A KR 840005111A
Authority
KR
South Korea
Prior art keywords
compound
formula
hydrogen
group
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019830002511A
Other languages
English (en)
Korean (ko)
Inventor
콜린 임메트 죤 (외 3)
Original Assignee
데비드 마틴워터스
스미스 크라인 앤드 프랜취 라보라토리스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838300476A external-priority patent/GB8300476D0/en
Application filed by 데비드 마틴워터스, 스미스 크라인 앤드 프랜취 라보라토리스 리미티드 filed Critical 데비드 마틴워터스
Publication of KR840005111A publication Critical patent/KR840005111A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18Oxygen or sulfur atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1019830002511A 1982-06-05 1983-06-04 복소환식 화합물 Withdrawn KR840005111A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8216437 1982-06-05
GB8216437 1982-06-05
GB8300476 1983-01-08
GB838300476A GB8300476D0 (en) 1983-01-08 1983-01-08 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
KR840005111A true KR840005111A (ko) 1984-11-03

Family

ID=26283037

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830002511A Withdrawn KR840005111A (ko) 1982-06-05 1983-06-04 복소환식 화합물

Country Status (15)

Country Link
US (2) US4514568A (enrdf_load_html_response)
EP (1) EP0096517A3 (enrdf_load_html_response)
KR (1) KR840005111A (enrdf_load_html_response)
AU (1) AU1527583A (enrdf_load_html_response)
DD (1) DD209818A5 (enrdf_load_html_response)
DK (1) DK247783A (enrdf_load_html_response)
ES (2) ES8500244A1 (enrdf_load_html_response)
FI (1) FI831998L (enrdf_load_html_response)
GR (1) GR79299B (enrdf_load_html_response)
JO (1) JO1255B1 (enrdf_load_html_response)
NO (1) NO832016L (enrdf_load_html_response)
PL (1) PL242354A1 (enrdf_load_html_response)
PT (1) PT76791B (enrdf_load_html_response)
RO (1) RO86851B (enrdf_load_html_response)
ZW (1) ZW12783A1 (enrdf_load_html_response)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657906A (en) * 1982-06-05 1987-04-14 Smith Kline & French Laboratories Ltd. Heterocyclic compounds having inotropic activity
GB8332313D0 (en) * 1983-12-02 1984-01-11 Smith Kline French Lab Chemical compounds
US4697016A (en) * 1984-10-26 1987-09-29 Ciba-Geigy Corporation Intermediates for the preparation of a carboxylic acid
US4595766A (en) * 1984-10-26 1986-06-17 Ciba-Geigy Corporation Process for the preparation of an indoline carboxylic acid
JPS62198671A (ja) * 1986-02-25 1987-09-02 Toyo Jozo Co Ltd 1−置換アルキル1,2−ジヒドロ−2−ピラジノン誘導体
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
CN103601792B (zh) 2007-06-04 2016-06-29 协同医药品公司 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2009149279A2 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
CN102470127A (zh) * 2009-08-19 2012-05-23 埃姆比特生物科学公司 联芳基化合物和其使用方法
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012118972A2 (en) 2011-03-01 2012-09-07 Synegy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
HK1208681A1 (en) * 2012-06-12 2016-03-11 Abbvie Inc. Pyridinone and pyridazinone derivatives
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2913737A1 (en) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase c, method of making and using same
JP6694385B2 (ja) 2013-08-09 2020-05-13 アーデリクス,インコーポレーテッド リン酸塩輸送阻害のための化合物及び方法
EP3972599A1 (en) 2019-05-21 2022-03-30 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3745161A (en) * 1970-04-20 1973-07-10 Merck & Co Inc Phenyl-hydroxy-pyrazine carboxylic acids and derivatives

Also Published As

Publication number Publication date
FI831998A7 (fi) 1983-12-06
PL242354A1 (en) 1984-12-17
DK247783D0 (da) 1983-06-01
PT76791B (en) 1986-01-24
EP0096517A3 (en) 1985-04-03
RO86851A (ro) 1985-05-20
EP0096517A2 (en) 1983-12-21
AU1527583A (en) 1983-12-08
FI831998L (fi) 1983-12-06
ES522962A0 (es) 1984-10-01
DK247783A (da) 1983-12-06
ES8707507A1 (es) 1985-12-01
PT76791A (en) 1983-07-01
US4556711A (en) 1985-12-03
ES530024A0 (es) 1985-12-01
ZW12783A1 (en) 1983-08-24
JO1255B1 (en) 1985-04-20
GR79299B (enrdf_load_html_response) 1984-10-22
DD209818A5 (de) 1984-05-23
NO832016L (no) 1983-12-06
US4514568A (en) 1985-04-30
ES8500244A1 (es) 1984-10-01
FI831998A0 (fi) 1983-06-03
RO86851B (ro) 1985-05-31

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19830604

PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19870910

Patent event code: PE09021S01D

PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid