KR840004116A - 7β-(2D-2-아미노-2-카르복시-에틸티오아세트아미드)-7α-메톡시-3-(1-메틸-1H-테트라졸-5-일)-티오메틸-3-세펨-4-카르본산나트륨염 7수화물의 제조방법 - Google Patents
7β-(2D-2-아미노-2-카르복시-에틸티오아세트아미드)-7α-메톡시-3-(1-메틸-1H-테트라졸-5-일)-티오메틸-3-세펨-4-카르본산나트륨염 7수화물의 제조방법 Download PDFInfo
- Publication number
- KR840004116A KR840004116A KR1019830001321A KR830001321A KR840004116A KR 840004116 A KR840004116 A KR 840004116A KR 1019830001321 A KR1019830001321 A KR 1019830001321A KR 830001321 A KR830001321 A KR 830001321A KR 840004116 A KR840004116 A KR 840004116A
- Authority
- KR
- South Korea
- Prior art keywords
- thiomethyl
- tetrazol
- methoxy
- amino
- methyl
- Prior art date
Links
- -1 1-methyl-1H-tetrazol-5-yl Chemical group 0.000 title claims 3
- 229910052708 sodium Inorganic materials 0.000 title 1
- 239000011734 sodium Substances 0.000 title 1
- 239000007864 aqueous solution Substances 0.000 claims 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 238000001556 precipitation Methods 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 7β-(2D-2-아미노-2-카르복시에틸티오아세트아미드)-7α-메톡시-3-(1-메틸-1H-테트라졸-5-일)-티오메틸-3-세펨-4-카르본산나트륨염의 수용액 또는 수성용액을 PH 4.0-7.5로 조절하여 결정을 석출시킴을 특징으로 하는 7β-(2D-2-아미노-2-카르복시에틸티오아세트아미드)-7α-메톡시-3-(1-메틸-1H-테트라졸-5-일)-티오메틸-3-세펨-4-카르본산나트륨염 7수화물의 제조방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57080075A JPS58198489A (ja) | 1982-05-14 | 1982-05-14 | ７β−（２Ｄ−２−アミノ−２−カルボキシエチルチオアセトアミド）−７α−メトキシ−３−（１−メチル−１Ｈ−テトラゾ−ル−５−イル）−チオメチル−３−セフエム−４−カルボン酸ナトリウム塩の七水和物及びその製造方法 |
| JP57-80075 | 1982-05-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR840004116A true KR840004116A (ko) | 1984-10-06 |
| KR880001299B1 KR880001299B1 (ko) | 1988-07-22 |
Family
ID=13708087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019830001321A KR880001299B1 (ko) | 1982-05-14 | 1983-03-31 | 7β-(2D-2-아미노-2-카르복시-에틸티오아세트아미드)-7α-메톡시-3-(1-메틸-1H-테트라졸-5-일)-티오메틸-3-세펨-4-카르본산나트륨염 7수화물의 제조방법 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4555404A (ko) |
| EP (1) | EP0094639B1 (ko) |
| JP (1) | JPS58198489A (ko) |
| KR (1) | KR880001299B1 (ko) |
| DE (1) | DE3370802D1 (ko) |
| ES (1) | ES8407056A1 (ko) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7842791B2 (en) * | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
| CN102363621B (zh) * | 2011-06-17 | 2013-05-01 | 深圳信立泰药业股份有限公司 | 头孢米诺钠六水合物及其制备方法和含有该水合物的药物组合物 |
| CN103588787B (zh) * | 2013-10-18 | 2015-12-02 | 中国食品药品检定研究院 | 一种头孢米诺钠晶体及其制备方法与应用 |
| CN103819491B (zh) * | 2013-12-19 | 2016-01-20 | 悦康药业集团有限公司 | 一种头孢米诺钠晶型化合物 |
| CN110003240A (zh) * | 2019-05-06 | 2019-07-12 | 哈尔滨誉衡药业股份有限公司 | 一种头孢米诺钠原料及其制备方法和制剂 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5583791A (en) * | 1978-12-18 | 1980-06-24 | Meiji Seika Kaisha Ltd | 7-methoxycephalosporin derivative and its preparation |
| JPS5630986A (en) * | 1979-08-23 | 1981-03-28 | Meiji Seika Kaisha Ltd | Preparation of 7-methoxycephalosporin derivative and drug composition |
| US4329453A (en) * | 1979-10-02 | 1982-05-11 | Glaxo Group Limited | Cephalosporin antibiotic |
-
1982
- 1982-05-14 JP JP57080075A patent/JPS58198489A/ja active Granted
-
1983
- 1983-03-31 KR KR1019830001321A patent/KR880001299B1/ko not_active IP Right Cessation
- 1983-05-13 EP EP83104736A patent/EP0094639B1/en not_active Expired
- 1983-05-13 ES ES522388A patent/ES8407056A1/es not_active Expired
- 1983-05-13 DE DE8383104736T patent/DE3370802D1/de not_active Expired
- 1983-05-16 US US06/495,236 patent/US4555404A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0094639A3 (en) | 1984-12-12 |
| JPS58198489A (ja) | 1983-11-18 |
| KR880001299B1 (ko) | 1988-07-22 |
| EP0094639A2 (en) | 1983-11-23 |
| DE3370802D1 (en) | 1987-05-14 |
| JPH0144189B2 (ko) | 1989-09-26 |
| EP0094639B1 (en) | 1987-04-08 |
| ES522388A0 (es) | 1984-08-16 |
| US4555404A (en) | 1985-11-26 |
| ES8407056A1 (es) | 1984-08-16 |
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| J206 | Request for trial to confirm the scope of a patent right | ||
| J121 | Written withdrawal of request for trial | ||
| FPAY | Annual fee payment |
Payment date: 20020615 Year of fee payment: 15 |
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| EXPY | Expiration of term |