KR830001900A - 페닐모르판과 그의 중간물질및 제조방법 - Google Patents
페닐모르판과 그의 중간물질및 제조방법 Download PDFInfo
- Publication number
- KR830001900A KR830001900A KR1019800001021A KR800001021A KR830001900A KR 830001900 A KR830001900 A KR 830001900A KR 1019800001021 A KR1019800001021 A KR 1019800001021A KR 800001021 A KR800001021 A KR 800001021A KR 830001900 A KR830001900 A KR 830001900A
- Authority
- KR
- South Korea
- Prior art keywords
- hydrogen
- formula
- phenylmorphane
- alkyl
- iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000000543 intermediate Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 239000001257 hydrogen Substances 0.000 claims 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229940100198 alkylating agent Drugs 0.000 claims 1
- 239000002168 alkylating agent Substances 0.000 claims 1
- 230000002152 alkylating effect Effects 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 150000007530 organic bases Chemical class 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1952779A | 1979-03-12 | 1979-03-12 | |
| US19,527 | 1979-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR830001900A true KR830001900A (ko) | 1983-05-19 |
Family
ID=21793680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019800001021A Ceased KR830001900A (ko) | 1979-03-12 | 1980-03-12 | 페닐모르판과 그의 중간물질및 제조방법 |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP0059989A1 (enExample) |
| JP (1) | JPS55124768A (enExample) |
| KR (1) | KR830001900A (enExample) |
| BE (1) | BE882152A (enExample) |
| CA (1) | CA1148150A (enExample) |
| FR (1) | FR2451368A1 (enExample) |
| GB (2) | GB2045248B (enExample) |
| HU (1) | HU179836B (enExample) |
| IL (1) | IL59553A0 (enExample) |
| IT (1) | IT1129740B (enExample) |
| LU (1) | LU82235A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0652811B2 (ja) * | 1984-07-04 | 1994-07-06 | 松下電器産業株式会社 | 高電圧発生装置 |
| US5087214A (en) * | 1991-05-21 | 1992-02-11 | United Technologies Automotive, Inc. | Battery terminal connector |
| US6900228B1 (en) | 1998-03-10 | 2005-05-31 | Research Triangle Institute | Opiate compounds, methods of making and methods of use |
| CA2324418C (en) * | 1998-03-10 | 2010-02-02 | Research Triangle Institute | Novel opiate compounds, methods of making and methods of use |
| AU2572800A (en) | 1999-02-18 | 2000-09-04 | Hisamitsu Pharmaceutical Co. Inc. | Morphan derivatives or salts thereof and medicinal compositions containing the same |
| TW200306189A (en) | 2002-03-21 | 2003-11-16 | Merz Pharma Gmbh & Co Kgaa | Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR206937A1 (es) * | 1974-09-06 | 1976-08-31 | Lilly Co Eli | Procedimiento para preparar compuestos de 1-sustituido-4-alquil-4-fenil-piperidina |
-
1980
- 1980-03-07 IL IL59553A patent/IL59553A0/xx unknown
- 1980-03-07 FR FR8005179A patent/FR2451368A1/fr active Granted
- 1980-03-10 BE BE1/9743A patent/BE882152A/fr not_active IP Right Cessation
- 1980-03-10 HU HU8080561A patent/HU179836B/hu unknown
- 1980-03-10 IT IT20473/80A patent/IT1129740B/it active
- 1980-03-10 CA CA000347364A patent/CA1148150A/en not_active Expired
- 1980-03-10 LU LU82235A patent/LU82235A1/fr unknown
- 1980-03-11 EP EP82102714A patent/EP0059989A1/en not_active Ceased
- 1980-03-11 JP JP3256680A patent/JPS55124768A/ja active Pending
- 1980-03-11 GB GB8008172A patent/GB2045248B/en not_active Expired
- 1980-03-11 EP EP80300746A patent/EP0018077A3/en not_active Ceased
- 1980-03-12 KR KR1019800001021A patent/KR830001900A/ko not_active Ceased
-
1982
- 1982-09-23 GB GB08227192A patent/GB2111976B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2045248B (en) | 1983-05-05 |
| CA1148150A (en) | 1983-06-14 |
| IT1129740B (it) | 1986-06-11 |
| EP0059989A1 (en) | 1982-09-15 |
| EP0018077A2 (en) | 1980-10-29 |
| GB2111976A (en) | 1983-07-13 |
| GB2045248A (en) | 1980-10-29 |
| FR2451368B1 (enExample) | 1983-03-18 |
| IL59553A0 (en) | 1980-06-30 |
| GB2111976B (en) | 1983-11-09 |
| FR2451368A1 (fr) | 1980-10-10 |
| IT8020473A0 (it) | 1980-03-10 |
| LU82235A1 (fr) | 1980-06-06 |
| JPS55124768A (en) | 1980-09-26 |
| EP0018077A3 (en) | 1980-11-26 |
| BE882152A (fr) | 1980-09-10 |
| HU179836B (en) | 1982-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19800312 |
|
| PG1501 | Laying open of application | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19840131 Patent event code: PE09021S01D |
|
| PE0601 | Decision on rejection of patent |
Patent event date: 19840914 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 19840131 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |