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Priority to KR7702466ApriorityCriticalpatent/KR790000100B1/en
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β-alanyl-L-histidine(I) with antiinflamatory and wound healing activity was manufd. Acrylic acid-protected carboxyl group was reacted with histidine in inactive org. solvent at -20-50≰C for 30 min-6 hr to give β-acryl-L-histidine and the addition reaction of NH3 was done at room temp-120≰C. β-alanyl-L-histidine was yielded by hydrolysis of the protected carboxyl group in alk. or acid.
KR7702466A1977-10-261977-10-26Process for preparing -alanyl-l-histidine
KR790000100B1
(en)
Amides isoxasole - 4 - carbon acid and amides of hidroxy-alkiliden ciano vinegar acid and the procedure for obtaining pharmaceutic preparations containing those compounds