KR20250153318A - 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스 - Google Patents

락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스

Info

Publication number
KR20250153318A
KR20250153318A KR1020257033657A KR20257033657A KR20250153318A KR 20250153318 A KR20250153318 A KR 20250153318A KR 1020257033657 A KR1020257033657 A KR 1020257033657A KR 20257033657 A KR20257033657 A KR 20257033657A KR 20250153318 A KR20250153318 A KR 20250153318A
Authority
KR
South Korea
Prior art keywords
shroud
receiver
electroporation device
needle
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020257033657A
Other languages
English (en)
Korean (ko)
Inventor
알레한드로 캠필로-어거스티
에두라르도 이. 호
네이선 러벨
스티븐 마스터슨
비트 스타델만
스테판 케머러
Original Assignee
이노비오 파마수티컬즈, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이노비오 파마수티컬즈, 인크. filed Critical 이노비오 파마수티컬즈, 인크.
Publication of KR20250153318A publication Critical patent/KR20250153318A/ko
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/0424—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00172—Connectors and adapters therefor
    • A61B2018/00178—Electrical connectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00184—Moving parts
    • A61B2018/00196—Moving parts reciprocating lengthwise
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A61B2018/143—Needle multiple needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1475—Electrodes retractable in or deployable from a housing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Prostheses (AREA)
KR1020257033657A 2015-12-30 2016-12-30 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스 Pending KR20250153318A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562272758P 2015-12-30 2015-12-30
US62/272,758 2015-12-30
PCT/US2016/069438 WO2017117508A1 (en) 2015-12-30 2016-12-30 Electroporation device with detachable needle array with lock-out system
KR1020247032017A KR102871106B1 (ko) 2015-12-30 2016-12-30 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020247032017A Division KR102871106B1 (ko) 2015-12-30 2016-12-30 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스

Publications (1)

Publication Number Publication Date
KR20250153318A true KR20250153318A (ko) 2025-10-24

Family

ID=59225790

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020257033657A Pending KR20250153318A (ko) 2015-12-30 2016-12-30 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스
KR1020187021055A Active KR102711822B1 (ko) 2015-12-30 2016-12-30 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스
KR1020247032017A Active KR102871106B1 (ko) 2015-12-30 2016-12-30 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020187021055A Active KR102711822B1 (ko) 2015-12-30 2016-12-30 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스
KR1020247032017A Active KR102871106B1 (ko) 2015-12-30 2016-12-30 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스

Country Status (17)

Country Link
US (3) US11071859B2 (https=)
EP (3) EP4311568A3 (https=)
JP (3) JP6961598B2 (https=)
KR (3) KR20250153318A (https=)
CN (2) CN109414580B (https=)
AU (3) AU2016381186B2 (https=)
CA (2) CA3009348A1 (https=)
ES (2) ES2970438T3 (https=)
IL (3) IL318805A (https=)
LT (1) LT3397337T (https=)
MX (2) MX394498B (https=)
PE (1) PE20181501A1 (https=)
PL (1) PL3397337T3 (https=)
PT (1) PT3397337T (https=)
RU (1) RU2746466C2 (https=)
SG (2) SG11201805381TA (https=)
WO (1) WO2017117508A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX394498B (es) 2015-12-30 2025-03-24 Inovio Pharmaceuticals Inc Dispositivo de electroporacion con arreglo de agujas extraible con sistema de bloqueo.
SE541651C2 (en) * 2017-07-28 2019-11-19 Scandinavian Chemotech Ab An electrode device and a needle electrode for use in delivery of electrical pulses to a desired tissue of a mammal
US11590345B2 (en) 2017-08-08 2023-02-28 Pulse Biosciences, Inc. Treatment of tissue by the application of energy
US10850095B2 (en) 2017-08-08 2020-12-01 Pulse Biosciences, Inc. Treatment of tissue by the application of energy
US10857347B2 (en) * 2017-09-19 2020-12-08 Pulse Biosciences, Inc. Treatment instrument and high-voltage connectors for robotic surgical system
US12178496B2 (en) 2018-10-10 2024-12-31 Pulse Biosciences, Inc. Treatment of dermal glands by the application of non-thermal energy
US11571569B2 (en) 2019-02-15 2023-02-07 Pulse Biosciences, Inc. High-voltage catheters for sub-microsecond pulsing
KR20220098004A (ko) * 2019-11-11 2022-07-08 프레시전 인코포레이티드 전기천공 장치 및 방법
WO2022214664A1 (en) 2021-04-09 2022-10-13 Philogen S.P.A. Improved interferon-gamma mutant
USD977094S1 (en) * 2021-04-23 2023-01-31 Pacira Cryotech, Inc. Tip assembly for a cryogenic device
KR102777932B1 (ko) * 2022-03-07 2025-03-11 주식회사 노바메디 니들카트리지
WO2024023246A1 (en) 2022-07-28 2024-02-01 Philogen S.P.A. Antibody binding to pd1
EP4568997A1 (en) 2022-08-08 2025-06-18 ATB Therapeutics Humanized antibodies against cd79b
US12070588B2 (en) * 2022-09-07 2024-08-27 Inocuject Corp. Injector and injection method therefor
CN115770099B (zh) * 2022-12-16 2025-11-28 杭州维纳安可医疗科技有限责任公司 探针组件和电极装置及其使用方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050215941A1 (en) 2002-04-05 2005-09-29 Bernard Robert M Method and apparatus for delivery of therapeutic agents

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU649218B2 (en) * 1989-02-01 1994-05-19 Sero-Guard Corporation Disposable automatic hypodermic needle guard
US5320610A (en) * 1991-12-16 1994-06-14 Inbae Yoon Automatic retractable trocar with safety shield and method of use
US5360408A (en) * 1992-11-16 1994-11-01 Vaillancourt Vincent L Shielded hypodermic needle assembly and a shield assembly for a hypodermic needle
US5702359A (en) * 1995-06-06 1997-12-30 Genetronics, Inc. Needle electrodes for mediated delivery of drugs and genes
US5439440A (en) * 1993-04-01 1995-08-08 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US6055453A (en) * 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
US6569123B2 (en) * 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US6972002B2 (en) * 2000-04-28 2005-12-06 Specialized Health Products, Inc. Passively activated safety shield for a catheter insertion needle
ES2683629T3 (es) 2001-04-13 2018-09-27 Becton, Dickinson And Company Dispositivo de administración intradérmica de llenado previo con aguja oculta y protección pasiva
US20040204669A1 (en) * 2001-07-05 2004-10-14 Hofmann Gunter A. Apparatus for electroporation mediated delivery for drugs and genes
AU2003230601A1 (en) 2002-03-07 2003-09-22 Instituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Clinical syringe with electrical stimulation aspects
CA2422472A1 (en) * 2002-03-19 2003-09-19 Volker Niermann Needle assembly
AU2003226605A1 (en) * 2002-04-19 2003-11-03 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US20050070841A1 (en) * 2002-07-04 2005-03-31 Inovio As Electroporation device and injection apparatus
US7500963B2 (en) * 2003-07-22 2009-03-10 Safety Syringes, Inc. Systems and methods for automatic medical injection with safeguard
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
US20080058706A1 (en) * 2004-06-30 2008-03-06 Genetronics, Inc. Modular electroporation device with disposable electrode and drug delivery components
US20060036210A1 (en) * 2004-06-30 2006-02-16 Lei Zhang Modular electroporation device with disposable electrode and drug delivery components
US20090030364A1 (en) * 2005-02-04 2009-01-29 The Johns Hopkins University Electroporation gene therapy gun system
CA2885759A1 (en) * 2006-06-30 2008-01-10 Abbvie Biotechnology Ltd. Automatic injection device
ES2360191T3 (es) * 2006-12-22 2011-06-01 Novo Nordisk A/S Ensamblaje de aguja protegible con un protector de seguridad pretensado.
NZ580997A (en) * 2007-04-27 2011-08-26 Echo Therapeutics Inc Dermal abrasion device with feedback electrode to deliver data on skin thickness and removable abrasion heads
US8361066B2 (en) 2009-01-12 2013-01-29 Ethicon Endo-Surgery, Inc. Electrical ablation devices
GB0914981D0 (en) * 2009-08-28 2009-09-30 Micromode Medical Ltd Electrostimulation device
WO2011076280A1 (de) * 2009-12-23 2011-06-30 Tecpharma Licensing Ag Injektionsvorrichtung mit einer nadelschutzhülse
AU2011223753B2 (en) 2010-03-01 2014-06-26 Inovio Pharmaceuticals, Inc. A tolerable and minimally invasive skin electroporation device
ES2548275T3 (es) * 2010-03-01 2015-10-15 Eli Lilly And Company Dispositivo de inyección automático con mecanismo de retardo que incluye un elemento de empuje de funcionamiento doble
KR102341551B1 (ko) * 2010-04-28 2021-12-21 이노비오 파마수티컬즈, 인크. 구강 점막 전기천공 장치 및 그 용도
KR101066883B1 (ko) 2010-07-01 2011-09-26 최종수 전류 인가형 멀티 주사 바늘 및 자동주사장치
US9289606B2 (en) * 2010-09-02 2016-03-22 St. Jude Medical, Atrial Fibrillation Division, Inc. System for electroporation therapy
US20120101475A1 (en) * 2010-10-21 2012-04-26 Meridian Medical Technologies, Inc. High Efficiency Auto-Injector
EP2468330A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489383A1 (en) * 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489384A1 (en) * 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
CA2837214C (en) 2011-06-28 2021-06-01 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
WO2013166203A2 (en) * 2012-05-01 2013-11-07 Life Technologies Corporation Pippette devices, systems, and methods of use thereof
WO2014001318A2 (en) * 2012-06-29 2014-01-03 Novo Nordisk A/S Shield lock for spring driven injection device
WO2014066655A2 (en) * 2012-10-25 2014-05-01 Oncosec Medical Incorporation Electroporation device
WO2015089492A2 (en) 2013-12-13 2015-06-18 The Trustees Of The University Of Pennsylvania Dna antibody constructs and method of using same
GB2511317A (en) * 2013-02-27 2014-09-03 Owen Mumford Ltd Automatic injection device
MX394498B (es) * 2015-12-30 2025-03-24 Inovio Pharmaceuticals Inc Dispositivo de electroporacion con arreglo de agujas extraible con sistema de bloqueo.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050215941A1 (en) 2002-04-05 2005-09-29 Bernard Robert M Method and apparatus for delivery of therapeutic agents

Also Published As

Publication number Publication date
MX2018008007A (es) 2019-03-28
KR102871106B1 (ko) 2025-10-15
ES2970438T3 (es) 2024-05-28
US20190009084A1 (en) 2019-01-10
JP7365383B2 (ja) 2023-10-19
JP2022002758A (ja) 2022-01-11
AU2016381186B2 (en) 2022-01-20
ES2843400T3 (es) 2021-07-16
RU2018127656A (ru) 2020-01-30
CN115475000B (zh) 2025-03-11
AU2022202620A1 (en) 2022-05-12
IL300102A (en) 2023-03-01
IL260072A (en) 2018-07-31
RU2018127656A3 (https=) 2020-05-14
CN109414580B (zh) 2022-09-20
SG11201805381TA (en) 2018-08-30
EP3799922B1 (en) 2023-08-30
JP2023168619A (ja) 2023-11-24
PE20181501A1 (es) 2018-09-18
SG10202110370PA (en) 2021-11-29
KR102711822B1 (ko) 2024-09-30
BR112018013312A2 (pt) 2018-12-11
PL3397337T3 (pl) 2021-01-25
AU2016381186A1 (en) 2018-07-12
US20230398350A1 (en) 2023-12-14
EP4311568A3 (en) 2024-03-20
RU2021109844A (ru) 2021-05-13
EP3397337B1 (en) 2020-07-29
EP3397337A4 (en) 2019-01-02
CA3200544A1 (en) 2017-07-06
EP4311568A2 (en) 2024-01-31
IL318805A (en) 2025-04-01
JP6961598B2 (ja) 2021-11-05
AU2022202620B2 (en) 2024-05-02
CA3009348A1 (en) 2017-07-06
US11883653B2 (en) 2024-01-30
IL260072B2 (en) 2023-06-01
CN109414580A (zh) 2019-03-01
KR20240148925A (ko) 2024-10-11
MX394498B (es) 2025-03-24
LT3397337T (lt) 2020-11-25
RU2746466C2 (ru) 2021-04-14
CN115475000A (zh) 2022-12-16
EP3397337A1 (en) 2018-11-07
IL300102B2 (en) 2025-07-01
IL300102B1 (en) 2025-03-01
US20210330967A1 (en) 2021-10-28
PT3397337T (pt) 2020-11-24
US11071859B2 (en) 2021-07-27
AU2024205496A1 (en) 2024-08-22
JP2019500158A (ja) 2019-01-10
MX2022009539A (es) 2022-09-09
EP3799922A1 (en) 2021-04-07
KR20180099751A (ko) 2018-09-05
WO2017117508A1 (en) 2017-07-06
RU2021109844A3 (https=) 2021-10-07

Similar Documents

Publication Publication Date Title
KR102871106B1 (ko) 락-아웃 시스템으로 분리가능한 바늘 어레이를 갖는 전기천공 디바이스
EP2929909B1 (en) Improved apparatus for electrically mediated delivery of therapeutic agents
HK40085257A (en) Electroporation device with detachable needle array with lock-out system
HK40085257B (zh) 具有带锁住系统的可拆卸针阵列的电穿孔装置
RU2785651C2 (ru) Устройство для электропорации со съемной игольчатой насадкой с системой блокирования в убранном положении
HK40001044A (en) Electroporation device with detachable needle array with lock-out system
HK40001044B (en) Electroporation device with detachable needle array with lock-out system
BR122023017841B1 (pt) Conjunto de agulhas para um dispostivo de eletroporação
BR112018013312B1 (pt) Dispositivo de eletroporação com conjunto de agulha destacável com sistema de travamento e sistema de eletrodeposição compreendendo o mesmo
JP2023506283A (ja) 医薬物質を注射するための注射装置およびこのような注射装置のための注射装填部
HK1216239B (en) Improved apparatus for electrically mediated delivery of therapeutic agents

Legal Events

Date Code Title Description
A16 Divisional, continuation or continuation in part application filed

Free format text: ST27 STATUS EVENT CODE: A-0-1-A10-A16-DIV-PA0104 (AS PROVIDED BY THE NATIONAL OFFICE)

PA0104 Divisional application for international application

St.27 status event code: A-0-1-A10-A16-div-PA0104

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

Q12 Application published

Free format text: ST27 STATUS EVENT CODE: A-1-1-Q10-Q12-NAP-PG1501 (AS PROVIDED BY THE NATIONAL OFFICE)

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D11-EXM-PA0201 (AS PROVIDED BY THE NATIONAL OFFICE)

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13 Application amended

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201