BR112018013312A2 - dispositivo de eletroporação com conjunto de agulha destacável com sistema de travamento - Google Patents

dispositivo de eletroporação com conjunto de agulha destacável com sistema de travamento

Info

Publication number
BR112018013312A2
BR112018013312A2 BR112018013312-4A BR112018013312A BR112018013312A2 BR 112018013312 A2 BR112018013312 A2 BR 112018013312A2 BR 112018013312 A BR112018013312 A BR 112018013312A BR 112018013312 A2 BR112018013312 A2 BR 112018013312A2
Authority
BR
Brazil
Prior art keywords
needle assembly
guard
electroporation device
locking system
movable
Prior art date
Application number
BR112018013312-4A
Other languages
English (en)
Inventor
Campillo-Agusti Alejandro
E. Ho Eduardo
Lovell Nathan
Masterson Steven
Stadelmann Beat
Kemmerrer Stephen
Original Assignee
Inovio Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inovio Pharmaceuticals, Inc. filed Critical Inovio Pharmaceuticals, Inc.
Publication of BR112018013312A2 publication Critical patent/BR112018013312A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/0424—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00172—Connectors and adapters therefor
    • A61B2018/00178—Electrical connectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00184—Moving parts
    • A61B2018/00196—Moving parts reciprocating lengthwise
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A61B2018/143—Needle multiple needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1475—Electrodes retractable in or deployable from a housing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Pathology (AREA)
  • Vascular Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Prostheses (AREA)

Abstract

um dispositivo de eletroporação com um conjunto de agulhas afixado de forma removível ao mesmo, o conjunto de agulhas tendo um corpo, uma proteção móvel em relação ao corpo entre uma posição de descanso e uma ou mais posições acionadas e um conjunto de trava automática. onde o conjunto de trava automática é ajustável entre uma configuração travada, em que a proteção não é móvel em relação ao corpo e uma configuração destravada, em que a proteção é móvel em relação ao corpo e em que inclinar a proteção a partir da posição de descanso para a uma ou mais posições acionadas e de volta para a posição de descanso ajusta a trava automática a partir da configuração destravada para a configuração travada.
BR112018013312-4A 2015-12-30 2016-12-30 dispositivo de eletroporação com conjunto de agulha destacável com sistema de travamento BR112018013312A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562272758P 2015-12-30 2015-12-30
US62/272,758 2015-12-30
PCT/US2016/069438 WO2017117508A1 (en) 2015-12-30 2016-12-30 Electroporation device with detachable needle array with lock-out system

Publications (1)

Publication Number Publication Date
BR112018013312A2 true BR112018013312A2 (pt) 2018-12-11

Family

ID=59225790

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018013312-4A BR112018013312A2 (pt) 2015-12-30 2016-12-30 dispositivo de eletroporação com conjunto de agulha destacável com sistema de travamento

Country Status (18)

Country Link
US (3) US11071859B2 (pt)
EP (3) EP3397337B1 (pt)
JP (3) JP6961598B2 (pt)
KR (1) KR20180099751A (pt)
CN (2) CN109414580B (pt)
AU (2) AU2016381186B2 (pt)
BR (1) BR112018013312A2 (pt)
CA (2) CA3009348A1 (pt)
ES (2) ES2843400T3 (pt)
IL (2) IL300102A (pt)
LT (1) LT3397337T (pt)
MX (2) MX2018008007A (pt)
PE (1) PE20181501A1 (pt)
PL (1) PL3397337T3 (pt)
PT (1) PT3397337T (pt)
RU (1) RU2746466C2 (pt)
SG (2) SG11201805381TA (pt)
WO (1) WO2017117508A1 (pt)

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SE541651C2 (en) * 2017-07-28 2019-11-19 Scandinavian Chemotech Ab An electrode device and a needle electrode for use in delivery of electrical pulses to a desired tissue of a mammal
US11590345B2 (en) 2017-08-08 2023-02-28 Pulse Biosciences, Inc. Treatment of tissue by the application of energy
US10850095B2 (en) 2017-08-08 2020-12-01 Pulse Biosciences, Inc. Treatment of tissue by the application of energy
US10857347B2 (en) 2017-09-19 2020-12-08 Pulse Biosciences, Inc. Treatment instrument and high-voltage connectors for robotic surgical system
EP3863710A4 (en) * 2018-10-10 2021-12-01 Pulse Biosciences, Inc. TREATMENT OF SKIN GLANDS THROUGH THE APPLICATION OF NON THERMAL ENERGY
US11571569B2 (en) 2019-02-15 2023-02-07 Pulse Biosciences, Inc. High-voltage catheters for sub-microsecond pulsing
CA3157944A1 (en) * 2019-11-11 2021-05-20 Bryan Butman Electroporation apparatus and method
WO2022214664A1 (en) 2021-04-09 2022-10-13 Philogen S.P.A. Improved interferon-gamma mutant
USD977094S1 (en) * 2021-04-23 2023-01-31 Pacira Cryotech, Inc. Tip assembly for a cryogenic device
WO2024023246A1 (en) 2022-07-28 2024-02-01 Philogen S.P.A. Antibody binding to pd1
WO2024033362A1 (en) 2022-08-08 2024-02-15 Atb Therapeutics Humanized antibodies against cd79b

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Also Published As

Publication number Publication date
CA3009348A1 (en) 2017-07-06
PT3397337T (pt) 2020-11-24
JP7365383B2 (ja) 2023-10-19
JP2023168619A (ja) 2023-11-24
AU2016381186B2 (en) 2022-01-20
KR20180099751A (ko) 2018-09-05
JP2022002758A (ja) 2022-01-11
JP2019500158A (ja) 2019-01-10
ES2970438T3 (es) 2024-05-28
SG11201805381TA (en) 2018-08-30
EP3799922B1 (en) 2023-08-30
AU2016381186A1 (en) 2018-07-12
US20230398350A1 (en) 2023-12-14
LT3397337T (lt) 2020-11-25
PL3397337T3 (pl) 2021-01-25
EP3799922A1 (en) 2021-04-07
US11071859B2 (en) 2021-07-27
MX2018008007A (es) 2019-03-28
RU2746466C2 (ru) 2021-04-14
CN109414580B (zh) 2022-09-20
US11883653B2 (en) 2024-01-30
MX2022009539A (es) 2022-09-09
SG10202110370PA (en) 2021-11-29
RU2018127656A3 (pt) 2020-05-14
EP3397337B1 (en) 2020-07-29
AU2022202620A1 (en) 2022-05-12
EP4311568A2 (en) 2024-01-31
WO2017117508A1 (en) 2017-07-06
US20210330967A1 (en) 2021-10-28
RU2018127656A (ru) 2020-01-30
RU2021109844A (ru) 2021-05-13
US20190009084A1 (en) 2019-01-10
JP6961598B2 (ja) 2021-11-05
AU2022202620B2 (en) 2024-05-02
ES2843400T3 (es) 2021-07-16
IL260072B2 (en) 2023-06-01
PE20181501A1 (es) 2018-09-18
IL300102A (en) 2023-03-01
EP3397337A4 (en) 2019-01-02
EP3397337A1 (en) 2018-11-07
EP4311568A3 (en) 2024-03-20
CA3200544A1 (en) 2017-07-06
CN109414580A (zh) 2019-03-01
RU2021109844A3 (pt) 2021-10-07
IL260072A (en) 2018-07-31
CN115475000A (zh) 2022-12-16

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B154 Notification of filing of divisional application [chapter 15.50 patent gazette]

Free format text: O PEDIDO FOI DIVIDIDO NO BR122023017841-6 PROTOCOLO 870230078075 EM 01/09/2023 18:39.

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]