KR20240036213A - Baby bottom cleanser composition Composition comprising ginger and herbal extract for anti-bacteria - Google Patents

Abstract

The present invention relates to an antibacterial baby's butt cleaner composition containing ginger and herb extract, wherein the composition contains a combination of ginger supercritical extract, oregano leaf extract, achyranthes extract, herbal extract, and Lactobacillus fermentation filtrate, respectively. It has excellent antibacterial and antifungal properties and excellent cleaning power compared to the single extract of .
In addition, it has multiple functionalities such as skin soothing and regeneration, so it can be easily used as a cosmetic composition for various purposes.

Description

{Baby bottom cleanser composition Composition comprising ginger and herbal extract for anti-bacteria}

The present invention relates to an antibacterial baby butt cleaner composition containing ginger and herb extract.

The skin is a part of the body that is directly exposed to the external environment. It not only acts as a protective layer to protect the important organs of our body, but also regulates moisture evaporation and protects the body from external infections. Meanwhile, recently developed body cleansers have focused only on antibacterial and cleansing properties due to fears about various viruses and infectious diseases, and have mainly focused on enhancing the short-term cleansing effect. To this end, stronger chemical surfactants, chemical preservatives to reduce raw materials, artificial fragrances, and artificial colors are added, which breaks the oil-water balance, causes a burning sensation, or removes more dead skin cells than necessary, making the skin more vulnerable to external infections.

Therefore, in the case of infants with sensitive skin, teenagers in puberty, children and adults suffering from atopy, etc., the preference for hypoallergenic and non-irritating products suitable for sensitive skin is increasing day by day. However, when using hypoallergenic raw materials, the economic feasibility of the final product may be poor, or it may be a limitation of natural products, and the quality may not always be guaranteed the same due to sanitary conditions at the time of manufacture, so their use may be limited.

Accordingly, the present inventors used a method of mixing and applying various herbal extracts without including chemical surfactants, chemical preservatives, artificial fragrances, and artificial pigments, and introduced them into human body cleansers to provide excellent antibacterial and antifungal activity while having minimal skin side effects. The present invention was completed by manufacturing an optimal baby butt cleaner composition that can produce skin soothing, moisturizing, and regenerative effects.

Republic of Korea Patent No. 1837020 (Title of Invention: Method for isolating high-purity saponin from fruitless fruits and cosmetic composition containing the same, Applicant: TN Co., Ltd., Registration date: 2017.02.14) Republic of Korea Registered Patent No. 1211937 (Title of Invention: Functional fermented wild wild plants with anti-inflammatory effect using extracts of 101 wild wild plants, Applicant: Delene Co., Ltd., Registration date: 2012.09.18) Republic of Korea Registered Patent No. 1347910 (Title of invention: Food composition, cosmetic composition and pharmaceutical composition containing supercritical ginger extract and fermented water parsley extract, Applicant: Keimyung University Industrial-Academic Cooperation Foundation, Registration date: 2012.01.31.) Republic of Korea Patent No. 0285781 (Title of invention: Essential oil composition with antibacterial and antifungal activity, Applicant: Choi Young-shin, Registration date: 1998.06.09.)

The purpose of the present invention is to provide an antibacterial baby butt cleaner composition containing ginger and herb extract.

The present invention relates to an antibacterial baby butt cleaner composition containing ginger and herb extract.

Preferably, the ginger and herb extract may be a mixed extract of ginger supercritical extract, oregano leaf extract, radish extract, medicinal buckwheat extract, and Lactobacillus fermentation filtrate. More preferably, the extract is based on 100 parts by weight of ginger supercritical extract, 5 to 30 parts by weight of oregano leaf extract, 2,500 to 2,800 parts by weight of sterile extract, 1,000 to 1,700 parts by weight of herbal extract, and 5 to 30 parts by weight of Lactobacillus fermentation filtrate. Parts by weight may be mixed.

Preferably, the extract may have antibacterial effect against Escherichia coli , Staphylococcus aureus , or Gardnerella vaginalis .

The extract may have antifungal efficacy. Preferably, it is characterized by antifungal efficacy against Candida albicans .

The extract may have a skin soothing effect, and the extract may also have a skin regenerative effect.

Accordingly, the present invention may relate to a cosmetic composition containing the above composition and having antibacterial, antifungal, skin soothing, or skin regenerative effects.

The ginger supercritical extract may be extracted by supercritical extraction of ginger powder using supercritical carbon dioxide at a temperature of 35 to 55°C and a pressure of 100 to 400 bar at a flow rate of 1 to 3 mL/min for 1 to 3 hours. . Through this extraction method, oil-like supercritical ginger extract can be obtained with a yield of 2.5 to 3.0% by weight.

The ginger powder may have an average particle size of 50 to 500 μm.

Herbs used in the preparation of extract in the present invention include oregano leaves, radish, and herbal medicine.

The extract of the present invention may include a mixture of Lactobacillus fermentation filtrate. The Lactobacillus fermented product may be a liquid obtained by sonicating Lactobacillus cells. More preferably, the strain cells obtained by centrifuging the culture medium of Lactobacillus strains cultured in MRS medium are diluted with 10 to 20 times the weight of distilled water, sonicated, and further centrifuged under the same conditions to obtain a liquid and filtered. It may be. The ultrasonic waves can be processed for 5 to 15 minutes using an ultrasonicator that generates ultrasonic waves with an intensity of 35 to 39 kHz. Each of the above centrifugations can be performed at 2 to 5°C and 1000 to 15000 rpm for 10 to 30 minutes. The liquid obtained from the second centrifugation can be filtered using a membrane filter. The membrane filter may have a filtration membrane with a pore size of 0.1 to 10 μm.

The Lactobacillus genus strains include Lactobacillus acidophilus, Lactobacillus bulgaricus , Lactobacillus paracasei , Lactobacillus casei , and Lactobacillus fermentum . ), Lactobacillus gasseri , Lactobacillus helveticus, Lactobacillus rhamnosus , Lactobacillus johnsonii , Lactobacillus plantarum and lactobacillus It may be selected from Bacillus reuteri ( Lactobacillus reuteri ).

Each of the above herbal extracts can be extracted from herbal raw materials using water, C1 to C4 alcohol, or a mixed solution thereof as a solvent. The C1 to C4 alcohol may be selected from the group consisting of methanol, ethanol, propanol, isopropanol, butanol, and isobutanol. Preferably, the extract may be extracted using an aqueous alcohol solution as a solvent. More preferably, it may be a 50-80% (v/v) alcohol aqueous solution, and most preferably, it may be a 50-80% (v/v) ethanol aqueous solution.

Water, C1 to C4 alcohol, or a mixed solution thereof used in the production of the herbal extract can be used in an amount of 1 to 40 times the volume (1 to 40 liters per kg) based on the weight of the herb used, and preferably 5 to 40 times the volume. You can use it. Extraction conditions for the herbal extract may be 1 minute to 48 hours at 20 to 100°C. The above process can be repeated 1 to 4 times.

In addition, as a common method in the art, the extract of water, C1 to C4 alcohol, or a mixture thereof of the herbal raw material is dissolved in water, and then a group consisting of n-hexane, methylene chloride, acetone, chloroform, ethyl acetate, and n-butanol. It can be prepared as a fraction by additional fractionation using one or more solvents selected from among.

The production temperature of the extract or fraction thereof may be 20 to 100° C., but is not limited thereto. The extraction or fractionation time is not particularly limited, but is preferably extracted within 10 minutes to 2 days, and the extraction device may be a conventional extraction device, an ultrasonic grinding extractor, or a fractionator. The extract or fraction prepared in this way can be dried with hot air, dried under reduced pressure, or freeze-dried to remove the solvent. The extract or fraction from which the solvent has been removed can be dissolved in butylene glycol or its aqueous solution and applied to cosmetics. At this time, more glycerin may be included.

Additionally, the extract or fraction can be purified and used using column chromatography.

The chromatography includes silica gel column chromatography, LH-20 column chromatography, ion exchange resin chromatography, and medium pressure liquid chromatography. chromatography), thin layer chromatography (TLC), silica gel vacuum liquid chromatography, and high performance liquid chromatography.

The formulation of the cosmetic composition may be any formulation commonly manufactured in the art, including essence, lotion, emulsion, pack, hand cream, foot cream, lip balm, lipstick, eye shadow, eyeliner, and eyebrow pencil. , blusher, highlighter, general lotion, skin, cream, serum, beauty soap, softening lotion, medicated lotion, body cleanser, cleansing foam, cleansing lotion, gel, cleansing oil, cleansing cream, shampoo, conditioner, hair treatment, hair You can provide a selection from lotions, cleansing tissues and cleansing water.

More specifically, when the formulation of the cosmetic composition of the present invention is a paste, cream or gel, animal fiber, plant fiber, wax, paraffin, starch, tragacanth, cellulose derivative, polyethylene glycol, silicone, bentonite, and silica are used as carrier ingredients. , talc or zinc oxide can be used. When the formulation of the cosmetic composition of the present invention is powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder can be used as the carrier ingredient. In particular, when the cosmetic composition is a spray, chlorofluorohydride may be used as a carrier ingredient. It may contain propellants such as carbon, propane-butane or dimethyl ether. When the formulation of the cosmetic composition of the present invention is a solution or emulsion, a solvent, solvating agent or emulsifying agent is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene. These include fatty acid esters of glycol, 1,3-butylglycol oil, glycerol aliphatic esters, polyethylene glycol or sorbitan. When the formulation of the cosmetic composition of the present invention is a suspension, the carrier component includes water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester, and polyoxyethylene sorbitan ester, Microcrystalline cellulose, aluminum metahydroxide, bentonite, agar, or tracant may be used. When the formulation of the cosmetic composition of the present invention is a surfactant-containing cleansing agent, the carrier ingredients include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, acethionate, imidazolinium derivative, methyl taurate, and sarcosinate. , fatty acid amide ether sulfate, alkylamidobetaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, linoline derivative, or ethoxylated glycerol fatty acid ester can be used. The cosmetic composition of the present invention may further contain excipients including fluorescent substances, fungicides, hydrotropes-inducing substances, moisturizers, fragrances, fragrance carriers, proteins, solubilizers, sugar derivatives, sunscreens, vitamins, plant extracts, etc. . The amount of the above ingredients can be selected depending on the formulation or purpose of use within a range that does not impair the inherent effect of the cosmetic composition. The amount of the ingredients added may be, for example, 0.1 to 10% by weight, preferably 0.1 to 6% by weight, based on the total weight of the composition, but is not limited thereto.

The baby butt cleaner of the present invention may also preferably include a mixed extract of the above ginger and herb extracts, 1,2-hexanediol, disodium EDTA, hydroxyethylcellulose, cocoglucoside, and decylglucoside. More preferably, 1 to 5% by weight of the mixed extract of the ginger and herb extract, 0.0001 to 0.1% by weight of 1,2-hexanediol, 0.001 to 0.1% by weight of disodium EDTA, 1 to 3% by weight of hydroxyethylcellulose, and cocoa. It may contain 0.1 to 2% by weight of glucoside and 0.1 to 1% by weight of decylglucoside.

The present invention relates to an antibacterial baby's butt cleanser composition containing ginger and herb extract, wherein the composition contains a combination of ginger supercritical extract, oregano leaf extract, Amurium extract, medicinal root extract, and Lactobacillus fermentation filtrate, respectively. It has excellent antibacterial and antifungal properties and excellent cleaning power compared to the single extract of . In addition, it has multiple functionalities such as skin soothing and regeneration, so it can be easily used as a cosmetic composition for various purposes.

Hereinafter, preferred embodiments of the present invention will be described in detail. However, the present invention is not limited to the embodiments described herein and may be embodied in other forms. Rather, it is provided to ensure that the content introduced here is thorough and complete, and to sufficiently convey the spirit of the present invention to those skilled in the art.

<Preparation Example 1. Preparation of supercritical ginger extract>

Using a supercritical fluid extraction device (SFT-100XW, Supercritical Fluid Technologies, Inc., Newark, DE, USA), 18 g of ginger powder with an average particle size of 50 to 500 ㎛ was extracted by placing it in a 100 mL extraction tank. The sample extraction conditions were conducted at 45°C and pressure maintained at 100 bar, and the carbon dioxide flow rate was 2 mL/min for 2 hours in dynamic mode, and the extract was immediately placed in a vial. The obtained ginger extract was concentrated under reduced pressure and, if necessary, dissolved in butylene glycol or its aqueous solution for use.

<Preparation Example 2. Preparation of herbal extract and Lactobacillus fermentation filtrate>

Oregano leaf extract, radish extract, Yammil extract, and Lactobacillus fermentation filtrate were prepared.

For this purpose, each herbal raw material such as oregano leaves, radish, and medicinal buckwheat was purchased in a dried state, immersed in 10 times the weight of 70% (v/v) ethanol aqueous solution, left at 70°C for 24 hours, and only the liquid phase was obtained and concentrated under reduced pressure. It was prepared in extract form. Afterwards, it was used by dissolving it in butylene glycol or its aqueous solution as needed.

To prepare Lactobacillus fermentation filtrate, first, a Lactobacillus plantarum strain for typical dairy fermentation was purchased and cultured in MRS medium. Afterwards, the culture medium was centrifuged at 4°C and 10,000 rpm for 20 minutes to obtain bacterial cells, and then the bacterial cells were diluted with 10 times the weight of distilled water and sonicated for 10 minutes using an ultrasonicator (37 kHz). After sonication, centrifugation was performed again at 4°C and 10,000 rpm for 20 minutes under the same conditions, and the liquid was collected and filtered through a 2 μm filtration membrane to obtain Lactobacillus fermentation filtrate. The obtained filtrate was concentrated under reduced pressure and then used by dissolving in butylene glycol or its aqueous solution as needed.

<Examples 1 to 5>

Each raw material was mixed under the conditions in Table 1 below and dissolved in 10 times the weight of a 30% (v/v) butylene glycol aqueous solution.

ginger supercritical
Extract (g) oregano leaves
Extract (g) no patient
Extract (g) Weak buckwheat
Extract (g) Lactobacillus
Fermentation filtrate (g) total
(g) Example 1 100 14 2660 1190 15 3979 Example 2 100 10 2500 1364 5 3979 Example 3 100 20 2600 1229 30 3979 Example 4 100 5 2800 1064 10 3979 Example 5 100 30 2200 1629 20 3979

<Comparative Examples 1 to 5>

Each raw material was mixed under the conditions in Table 2 below and dissolved in 10 times the weight of a 30% (v/v) butylene glycol aqueous solution.

ginger supercritical
Extract (g) oregano leaves
Extract (g) no patient
Extract (g) Weak buckwheat
Extract (g) Lactobacillus
Fermentation filtrate (g) total
(g) Comparative Example 1 100 0 2000 1879 0 3979 Comparative Example 2 100 0 3779 0 100 3979 Comparative Example 3 100 100 0 3779 0 3979 Comparative Example 4 0 20 1500 2359 100 3979 Comparative Example 5 100 1000 1200 679 1000 3979

<Experimental Example 1. Confirmation of antibacterial/antifungal efficacy>

Antibacterial activity was confirmed using the RDA (radial diffusion assay) test method. The RDA method involves culturing bacteria on a sterilized underlay gel consisting of citrate phosphate buffer (9 mM sodium phosphate, 1 mM sodium citrate, pH 7.4), 1% (w/v) type Ⅰ (low electroendosmosis) agarose, and 0.03% TSB. ( ⁴ After cultivating each extract for 3 hours at 37°C to ensure uniform diffusion, 10 ml of overlay agar (6% TSB, 1% agarose) was poured and cultured again at 37°C to confirm the clear zone and measure the diameter. The representative strains used were Escherichia coli , Staphylococcus aureus , and Gardnerella vaginalis, and the fungi used were Candida albicans . The results are shown in Table 3.

sample Antibacterial ring diameter (mm) Escherichia coli Staphylococcus aureus Candida albicans Gardnerella vaginalis Example 1 Extract 27.1 25.4 18.2 22.1 Example 2 Extract 31.4 25.1 19.4 19.4 Example 3 Extract 29.2 27.2 16.2 18.4 Example 4 Extract 28.1 25.1 21.2 17.5 Example 5 Extract 28.2 23.3 22.5 16.0 Comparative Example 1 Extract 4.4 1.2 3.5 2.6 Comparative Example 2 Extract 3.2 11.3 0.0 0.0 Comparative Example 3 Extract 9.5 2.2 0.0 5.2 Comparative Example 4 Extract 11.6 12.3 2.1 4.1 Comparative Example 5 Extract 14.1 12.3 11.0 12.5

Referring to Table 3, the extracts of Examples 1 to 5 of the present invention had antibacterial/antifungal effects against all bacteria or fungi tested.

<Experimental Example 3. Confirmation of skin soothing effect>

Human keratinocytes (HaCaT) were cultured in a 60 mm culture dish (corning) and then treated with 250 μM H ₂ O ₂ as a cell stimulant in HBSS (Hank's Balanced Salt Solution, Gibco) for 1 hour. At this time, H ₂ O ₂ It causes inflammation of skin cells and loss of barrier function, acting in the same way as causing erythema or contact dermatitis on human skin.

After replacing the medium, the extract samples were treated for 24 hours, RNA was isolated using QIAzol™ Lysis Reagent (Qiagen), and real-time PCR was performed. At this time, the treatment concentration of the final extract was 100 μg/ml.

sample Gene expression (%) IL-1α IL-6 Untreated group 16.2 14.2 H ₂ O ₂ 100.0 100.0 H ₂ O ₂ + Example 1 extract 41.2 42.4 H ₂ O ₂ + Example 2 extract 42.1 41.3 H ₂ O ₂ + Example 3 extract 44.2 34.0 H ₂ O ₂ + Example 4 extract 45.2 23.5 H ₂ O ₂ + Example 5 extract 38.3 45.2 H ₂ O ₂ + Comparative Example 1 Extract 75.2 85.2 H ₂ O ₂ + Comparative Example 2 Extract 84.2 89.3 H ₂ O ₂ + Comparative Example 3 extract 76.6 71.5 H ₂ O ₂ + Comparative Example 4 Extract 97.3 89.3 H ₂ O ₂ + Comparative Example 5 extract 68.2 69.2

As a result of the experiment, as shown in Table 4, it was confirmed that the expression levels of IL-Iα and IL-6 genes were significantly suppressed in the group treated with the extract of the present invention, confirming that there was a soothing effect on skin cells stimulated by H ₂ O ₂ there is.

Similar results were obtained even when this experiment was repeatedly conducted using 50 mJ/cm2 of UVB as a cell stimulator.

<Experimental Example 4. Confirmation of skin regeneration efficacy>

In order to measure the effect of each extract prepared in the present invention on the synthesis of collagen types I and IV, which have the greatest influence on the regeneration of skin cells, an experiment was conducted as follows.

A 96 well microtiter plate was coated at room temperature for 12 hours after injection of monoclonal anti-collagen I or IV Anti-body (2 μg/well/PBS). After blocking with blocking buffer for 1 hour at room temperature, each extract sample was treated with 100 ㎕ of culture medium (CM) of human keratinocyte (HaCaT) treated for 24 hours per well and reacted at room temperature for 90 minutes. . The final concentration of the extract sample treated with each cell culture medium was 100 μg/ml. Afterwards, polyclonal anti-collagen I or IV Anti-body was treated in each well and reacted at room temperature for 90 minutes, and then avidin-HRP was treated in each well and reacted at room temperature for 60 minutes.

After injecting 100 μL of Supersignal ELISA pico chemiluminescent substrate into each well and reacting for 10 minutes, the degree of luminescence was measured using an ELISA plate reader, and the type I of human keratinocyte (HaCaT) treated with each extract was measured. Alternatively, the results for IV collagen synthesis and secretion are shown in Table 5.

sample Collagen type I (%) Collagen type IV (%) Untreated group 100.0 100.0 Example 1 Extract 173.1 182.2 Example 2 Extract 213.2 182.0 Example 3 Extract 192.1 193.1 Example 4 Extract 187.0 186.2 Example 5 Extract 182.5 192.4 Comparative Example 1 Extract 112.4 121.0 Comparative Example 2 Extract 142.2 119.3 Comparative Example 3 Extract 132.1 121.1 Comparative Example 4 Extract 121.5 141.5 Comparative Example 5 Extract 151.0 151.2

As shown in Table 5, it can be confirmed that the extracts of Examples 1 to 5 have very excellent intracellular collagen biosynthesis efficacy, so the extract of the present invention can be used as a baby butt cleanser composition that provides excellent efficacy in soothing and regenerating skin cells. It is proven that there is.

<Manufacture of cosmetic composition formulation - baby butt cleaner>

In order to formulate a formulation that can be used practically, a baby butt cleaner was prepared by mixing each raw material at the content shown in Table 6 below.

Baby Butt Cleanser #1 Material name Addition amount (g) Mixed extract of Example 1 3.97 1,2-hexanediol 0.084 Disodium EDTA 0.03 Hydroxyethylcellulose 1.85 Coco Glucoside 0.85 Decyl Glucoside 0.35 Purified water remaining amount total amount 100.0

In addition, as shown in Table 7 below, a baby butt cleaner containing the raw materials in Table 6 was prepared by varying only each extract.

Formulation sample Baby Butt Cleanser #2 Example 2 Extract Contains Baby Butt Cleanser #3 Example 3 Extract Contains Baby Butt Cleanser #4 Example 4 Extract Contains Baby Butt Cleanser #5 Example 5 Extract Contains Comparison of baby butt cleaners #1 Comparative Example 1 Extract included Comparison of baby butt cleaners #2 Comparative Example 2 Extract included Comparison of baby butt cleaners #3 Comparative Example 3 Extract Contains Comparison of baby butt cleaners #4 Comparative Example 4 Extract Contains Comparison of baby butt cleaners #5 Comparative Example 5 Extract Contains

<Experimental Example 5. Confirmation of antibacterial/antifungal properties of baby butt cleaner>

Antibacterial and antifungal properties were confirmed using the baby butt cleaner prepared in the present invention. Each baby's butt cleaner was filled into a pump container dedicated to the gel formulation. Afterwards, in each experiment, the same volume of Escherichia coli and Candida albicans culture fluid was placed in contact with the palm of the person's hand, and then the baby's butt cleaner was pumped from each container, 5 mL of the cleaner was taken, and hands were washed according to the proper hand washing method of the Korea Disease Control and Prevention Agency. . The number of experimental subjects in each group was 5.

The number of each bacteria was measured immediately after contact with the culture medium and after washing. To measure the number of bacteria, the palm of the test subject was brought into contact with a plate medium for culturing Escherichia coli and Candida albicans , then cultured in an incubator for 24 hours, and the total number of bacteria was confirmed. The percentage removed through washing is shown in Table 8 below. indicated.

cleaning agent Removal rate (%) Escherichia coli Candida albicans Baby Butt Cleanser #1 99.99 99.99 Baby Butt Cleanser #2 99.99 99.99 Baby Butt Cleanser #3 99.99 99.99 Baby Butt Cleanser #4 99.99 99.99 Baby Butt Cleanser #5 99.99 99.99 Comparison of baby butt cleaners #1 73.35 79.04 Comparison of baby butt cleaners #2 73.04 63.45 Comparison of baby butt cleaners #3 69.13 72.36 Comparison of baby butt cleaners #4 75.12 71.32 Comparison of baby butt cleaners #5 82.36 83.03

As a result, it can be confirmed that the baby butt cleaner containing the extract of the present invention removes Escherichia coli and Candida albicans very effectively and has excellent cleaning ability.

Claims (8)

An antibacterial baby butt cleanser composition comprising a mixed extract of ginger supercritical extract, oregano leaf extract, radish extract, medicinal buckwheat extract, and Lactobacillus fermentation filtrate. According to paragraph 1,
The ginger supercritical extract is characterized in that ginger powder is extracted by supercritical extraction for 1 to 3 hours at a pressure of 100 to 400 bar at a flow rate of 1 to 3 mL/min at 35 to 55 ° C. using supercritical carbon dioxide. Antibacterial baby butt cleaner composition. According to paragraph 1,
The extract is an antibacterial baby butt cleaner composition characterized in that it has antibacterial effect against Escherichia coli, Staphylococcus aureus , or Gardnerella vaginalis . According to paragraph 1,
The extract is an antibacterial baby butt cleaner composition, characterized in that it has antifungal effect against Candida albicans . According to paragraph 1,
The extract is an antibacterial baby butt cleaner composition characterized in that it has a skin soothing effect. According to paragraph 1,
The extract is an antibacterial baby butt cleaner composition characterized in that it has a skin regenerative effect. A cosmetic composition for an antibacterial baby butt cleaner, characterized in that it contains the composition of any one of claims 1 to 6. In clause 7,
The cosmetic composition is an antibacterial baby butt cleaner cosmetic composition, characterized in that it has antifungal, skin soothing or skin regenerative effects.