KR20240013509A

KR20240013509A - 초음파 감응형 포피린-리포좀 및 이의 용도

초음파 감응형 포피린-리포좀 및 이의 용도 Download PDF

Info

Publication number: KR20240013509A
Authority: KR; South Korea
Prior art keywords: porphyrin; liposome; cancer; ultrasound; sensitive
Prior art date: 2022-07-22

Application number

KR1020220091126A

Other languages

English (en)

Korean (ko)

Inventor

정은아

김대현

Original Assignee

(주)아이엠지티

Priority date

2022-07-22

Filing date

2022-07-22

Publication date

2024-01-30

2022-07-22 Application filed by (주)아이엠지티 filed Critical (주)아이엠지티

2022-07-22 Priority to KR1020220091126A priority Critical patent/KR20240013509A/ko

2023-07-19 Priority to PCT/KR2023/010440 priority patent/WO2024019542A1/fr

2024-01-30 Publication of KR20240013509A publication Critical patent/KR20240013509A/ko

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GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 description 1
HSFQBFMEWSTNOW-UHFFFAOYSA-N sodium;carbanide Chemical group [CH3-].[Na+] HSFQBFMEWSTNOW-UHFFFAOYSA-N 0.000 description 1
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IZEUIYYDWBKERE-UHFFFAOYSA-N stigmasteryl acetate Natural products C1C=C2CC(OC(C)=O)CCC2(C)C2C1C1CCC(C(C)C=CC(CC)C(C)C)C1(C)CC2 IZEUIYYDWBKERE-UHFFFAOYSA-N 0.000 description 1
239000006190 sub-lingual tablet Substances 0.000 description 1
238000010254 subcutaneous injection Methods 0.000 description 1
239000007929 subcutaneous injection Substances 0.000 description 1
229940035023 sucrose monostearate Drugs 0.000 description 1
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150000008163 sugars Chemical class 0.000 description 1
239000007939 sustained release tablet Substances 0.000 description 1
238000002626 targeted therapy Methods 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
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JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
230000007704 transition Effects 0.000 description 1
YWYZEGXAUVWDED-UHFFFAOYSA-N triammonium citrate Chemical compound [NH4+].[NH4+].[NH4+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O YWYZEGXAUVWDED-UHFFFAOYSA-N 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
235000013337 tricalcium citrate Nutrition 0.000 description 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
210000000689 upper leg Anatomy 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
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229940100445 wheat starch Drugs 0.000 description 1
235000010447 xylitol Nutrition 0.000 description 1
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HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1