KR20240005714A - Sars-cov-2 항원을 표적화하는 펩티드 및 조작된 t 세포 수용체 및 사용 방법 - Google Patents

Sars-cov-2 항원을 표적화하는 펩티드 및 조작된 t 세포 수용체 및 사용 방법 Download PDF

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KR20240005714A
KR20240005714A KR1020237037284A KR20237037284A KR20240005714A KR 20240005714 A KR20240005714 A KR 20240005714A KR 1020237037284 A KR1020237037284 A KR 1020237037284A KR 20237037284 A KR20237037284 A KR 20237037284A KR 20240005714 A KR20240005714 A KR 20240005714A
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polypeptide
seq
tcr
amino acid
peptide
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Korean (ko)
Inventor
카시안 이
커 판
율룬 치우
Original Assignee
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템
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    • A—HUMAN NECESSITIES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A—HUMAN NECESSITIES
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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KR1020237037284A 2021-03-29 2022-03-29 Sars-cov-2 항원을 표적화하는 펩티드 및 조작된 t 세포 수용체 및 사용 방법 Pending KR20240005714A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163167433P 2021-03-29 2021-03-29
US63/167,433 2021-03-29
US202163210198P 2021-06-14 2021-06-14
US63/210,198 2021-06-14
US202263314870P 2022-02-28 2022-02-28
US63/314,870 2022-02-28
PCT/US2022/022324 WO2022212361A1 (en) 2021-03-29 2022-03-29 Peptides and engineered t cell receptors targeting sars-cov-2 antigens and methods of use

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KR20240005714A true KR20240005714A (ko) 2024-01-12

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KR1020237037284A Pending KR20240005714A (ko) 2021-03-29 2022-03-29 Sars-cov-2 항원을 표적화하는 펩티드 및 조작된 t 세포 수용체 및 사용 방법

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US (1) US20240293459A1 (cg-RX-API-DMAC7.html)
EP (1) EP4313139A4 (cg-RX-API-DMAC7.html)
JP (1) JP2024514477A (cg-RX-API-DMAC7.html)
KR (1) KR20240005714A (cg-RX-API-DMAC7.html)
AU (1) AU2022246811A1 (cg-RX-API-DMAC7.html)
WO (1) WO2022212361A1 (cg-RX-API-DMAC7.html)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
KR20250115147A (ko) 2024-01-23 2025-07-30 국립경국대학교 산학협력단 재조합 ＳＡＲＳ­ＣｏＶ­２ 렌티바이러스 벡터를 이용한 ＳＡＲＳ­ＣｏＶ­２ 자가면역 백신의 제조방법

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Publication number Priority date Publication date Assignee Title
EP4716699A2 (en) * 2023-05-22 2026-04-01 Board of Regents, The University of Texas System Peptides and engineered t cell receptors targeting brachyury antigen and methods of use
CN117659140B (zh) * 2023-10-26 2026-05-05 中国人民解放军海军军医大学 新冠病毒hla-a2限制性表位肽及应用
WO2026019786A1 (en) * 2024-07-16 2026-01-22 Board Of Regents, The University Of Texas System Peptides and engineered t cell receptors targeting brachyury antigen and methods of use
TW202615096A (zh) * 2024-07-19 2026-04-16 國立大學法人京都大學 SARS-CoV-2感染症治療及/或預防用細胞及其製法

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WO2004110349A2 (en) * 2003-05-14 2004-12-23 Siga Technologies, Inc. Sars t cell epitopes and methods for identifying same
MX2020001879A (es) * 2017-08-18 2020-07-29 Gritstone Oncology Inc Proteínas de fijación al antígeno que se dirigen a antígenos compartidos.
AU2018395397A1 (en) * 2017-12-28 2020-08-06 Gritstone Bio, Inc. Antigen-binding proteins targeting shared antigens
WO2024227034A1 (en) * 2023-04-27 2024-10-31 Serum Detect, Inc. T-cell receptor signatures indicative of early stages of cancer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250115147A (ko) 2024-01-23 2025-07-30 국립경국대학교 산학협력단 재조합 ＳＡＲＳ­ＣｏＶ­２ 렌티바이러스 벡터를 이용한 ＳＡＲＳ­ＣｏＶ­２ 자가면역 백신의 제조방법

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AU2022246811A1 (en) 2023-11-16
JP2024514477A (ja) 2024-04-02
EP4313139A4 (en) 2025-07-02
US20240293459A1 (en) 2024-09-05
WO2022212361A1 (en) 2022-10-06

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