KR20240004429A - B형 간염 치료용 렌티바이러스 벡터, 렌티바이러스 입자, 및 그의 제조 방법 및 그의 용도 - Google Patents

B형 간염 치료용 렌티바이러스 벡터, 렌티바이러스 입자, 및 그의 제조 방법 및 그의 용도 Download PDF

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Publication number
KR20240004429A
KR20240004429A KR1020237037652A KR20237037652A KR20240004429A KR 20240004429 A KR20240004429 A KR 20240004429A KR 1020237037652 A KR1020237037652 A KR 1020237037652A KR 20237037652 A KR20237037652 A KR 20237037652A KR 20240004429 A KR20240004429 A KR 20240004429A
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South Korea
Prior art keywords
hepatitis
lentiviral
antigen
pro
seq
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Pending
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KR1020237037652A
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Korean (ko)
Inventor
피에르 알랭 샤르노
마릴린 부르진
차오 추
예 톈
벤자맹 브쟁
Original Assignee
떼라벡띠스
상하이 진웨이 바이오테크놀로지 컴퍼니 리미티드
앵스띠뛰 파스퇴르
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Application filed by 떼라벡띠스, 상하이 진웨이 바이오테크놀로지 컴퍼니 리미티드, 앵스띠뛰 파스퇴르 filed Critical 떼라벡띠스
Publication of KR20240004429A publication Critical patent/KR20240004429A/ko
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    • AHUMAN NECESSITIES
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    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
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    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15051Methods of production or purification of viral material
    • C12N2740/15052Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Wood Science & Technology (AREA)
  • Communicable Diseases (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020237037652A 2021-04-07 2022-04-07 B형 간염 치료용 렌티바이러스 벡터, 렌티바이러스 입자, 및 그의 제조 방법 및 그의 용도 Pending KR20240004429A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110374234.2 2021-04-07
CN202110374234.2A CN114107393A (zh) 2021-04-07 2021-04-07 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用
PCT/EP2022/059281 WO2022214599A1 (en) 2021-04-07 2022-04-07 Lentiviral vector, lentiviral particle for treating hepatitis b and its preparation method and application thereof

Publications (1)

Publication Number Publication Date
KR20240004429A true KR20240004429A (ko) 2024-01-11

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KR1020237037652A Pending KR20240004429A (ko) 2021-04-07 2022-04-07 B형 간염 치료용 렌티바이러스 벡터, 렌티바이러스 입자, 및 그의 제조 방법 및 그의 용도

Country Status (11)

Country Link
US (1) US20250073332A1 (https=)
EP (1) EP4319805A1 (https=)
JP (1) JP2024516115A (https=)
KR (1) KR20240004429A (https=)
CN (2) CN114107393A (https=)
AU (1) AU2022255056A1 (https=)
BR (1) BR112023020732A2 (https=)
CA (1) CA3214383A1 (https=)
TW (1) TWI906499B (https=)
WO (1) WO2022214599A1 (https=)
ZA (1) ZA202309368B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024159517A1 (zh) * 2023-02-03 2024-08-08 南方科技大学 一种乙型肝炎mRNA及其疫苗与用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1081069C (zh) 1998-08-14 2002-03-20 饶纬华 乙型肝炎治疗性疫苗及其制备方法
US8158413B2 (en) 2005-10-17 2012-04-17 Institut Pasteur Lentiviral vector-based vaccine
WO2008103380A2 (en) * 2007-02-21 2008-08-28 Fox Chase Cancer Center Hepatitis b virus compositions and methods of use
DK2185192T3 (en) 2007-08-03 2019-02-18 Pasteur Institut LENTIVIRAL TRANSFER VECTORS AND THEIR MEDICAL USES
CN101502650B (zh) * 2009-03-10 2011-12-28 邢益平 密码子优化的乙型肝炎核酸疫苗
EP2666477A1 (en) 2012-05-23 2013-11-27 Theravectys Lentiviral vectors containing an MHC class I promoter
CA2849652C (en) 2011-09-26 2017-11-21 Theravectys Use of non-subtype b gag proteins for lentiviral packaging
RS61118B1 (sr) * 2016-01-12 2020-12-31 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh Sredstva i postupci za lečenje hbv
EP3276006A1 (en) * 2016-07-27 2018-01-31 Theravectys Lentiviral vectors for expression of hepatitis b virus (hbv) antigens
EP3532084A4 (en) * 2016-10-31 2020-05-27 Georgia State University Research Foundation, Inc. VIRUS-LIKE HEPATITIS-B-VIRUS-PRÄ-S-PROTEIN PARTICLE
CN106928372B (zh) * 2016-12-30 2019-09-13 北京大学深圳研究生院 乙肝重组抗原及其表达基因、构建方法、病毒样颗粒及其制备方法、应用与疫苗
CN107058346B (zh) * 2017-05-03 2021-01-29 李军涛 一种乙肝病毒表面抗原基因与表达载体及细胞株
CA3132601A1 (en) * 2019-03-05 2020-09-10 Glaxosmithkline Biologicals Sa Hepatitis b immunisation regimen and compositions

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Publication number Publication date
EP4319805A1 (en) 2024-02-14
TWI906499B (zh) 2025-12-01
AU2022255056A1 (en) 2023-10-26
CN115197969B (zh) 2023-09-01
WO2022214599A1 (en) 2022-10-13
ZA202309368B (en) 2025-03-26
CA3214383A1 (en) 2022-10-13
BR112023020732A2 (pt) 2024-01-09
TW202239963A (zh) 2022-10-16
US20250073332A1 (en) 2025-03-06
JP2024516115A (ja) 2024-04-12
CN115197969A (zh) 2022-10-18
CN114107393A (zh) 2022-03-01

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