CN114107393A - 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用 - Google Patents

一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用 Download PDF

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Publication number
CN114107393A
CN114107393A CN202110374234.2A CN202110374234A CN114107393A CN 114107393 A CN114107393 A CN 114107393A CN 202110374234 A CN202110374234 A CN 202110374234A CN 114107393 A CN114107393 A CN 114107393A
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China
Prior art keywords
hepatitis
pro
antigen
lentiviral
lentiviral vector
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Pending
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CN202110374234.2A
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English (en)
Chinese (zh)
Inventor
P·查尼奥
M·布尔吉娜
仇超
田晔
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Shanghai Jinwei Biotechnology Co ltd
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Shanghai Jinwei Biotechnology Co ltd
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Priority to CN202110374234.2A priority Critical patent/CN114107393A/zh
Publication of CN114107393A publication Critical patent/CN114107393A/zh
Priority to TW111113136A priority patent/TWI906499B/zh
Priority to CN202210359887.8A priority patent/CN115197969B/zh
Priority to PCT/EP2022/059281 priority patent/WO2022214599A1/en
Priority to KR1020237037652A priority patent/KR20240004429A/ko
Priority to US18/285,553 priority patent/US20250073332A1/en
Priority to JP2023562250A priority patent/JP2024516115A/ja
Priority to EP22716265.8A priority patent/EP4319805A1/en
Priority to AU2022255056A priority patent/AU2022255056A1/en
Priority to BR112023020732A priority patent/BR112023020732A2/pt
Priority to CA3214383A priority patent/CA3214383A1/en
Priority to ZA2023/09368A priority patent/ZA202309368B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
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    • AHUMAN NECESSITIES
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CN202110374234.2A 2021-04-07 2021-04-07 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用 Pending CN114107393A (zh)

Priority Applications (12)

Application Number Priority Date Filing Date Title
CN202110374234.2A CN114107393A (zh) 2021-04-07 2021-04-07 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用
TW111113136A TWI906499B (zh) 2021-04-07 2022-04-06 一種治療b型肝炎的慢病毒載體、慢病毒顆粒及其製備方法和應用
CN202210359887.8A CN115197969B (zh) 2021-04-07 2022-04-06 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用
CA3214383A CA3214383A1 (en) 2021-04-07 2022-04-07 Lentiviral vector, lentiviral particle for treating hepatitis b and its preparation method and application thereof
KR1020237037652A KR20240004429A (ko) 2021-04-07 2022-04-07 B형 간염 치료용 렌티바이러스 벡터, 렌티바이러스 입자, 및 그의 제조 방법 및 그의 용도
PCT/EP2022/059281 WO2022214599A1 (en) 2021-04-07 2022-04-07 Lentiviral vector, lentiviral particle for treating hepatitis b and its preparation method and application thereof
US18/285,553 US20250073332A1 (en) 2021-04-07 2022-04-07 Lentiviral vector, lentiviral particle for treating hepatitis b and its preparation method and application thereof
JP2023562250A JP2024516115A (ja) 2021-04-07 2022-04-07 レンチウイルスベクター、b型肝炎を処置する為のレンチウイルス粒子、並びにその調製方法及びその用途
EP22716265.8A EP4319805A1 (en) 2021-04-07 2022-04-07 Lentiviral vector, lentiviral particle for treating hepatitis b and its preparation method and application thereof
AU2022255056A AU2022255056A1 (en) 2021-04-07 2022-04-07 Lentiviral vector, lentiviral particle for treating hepatitis b and its preparation method and application thereof
BR112023020732A BR112023020732A2 (pt) 2021-04-07 2022-04-07 Vetor lentiviral para o tratamento da hepatite b, método e preparação de partículas lentivirais para o tratamento da mesma e composição farmacêutica para o tratamento e/ou prevenção da infecção pelo vírus da hepatite b
ZA2023/09368A ZA202309368B (en) 2021-04-07 2023-10-06 Lentiviral vector, lentiviral particle for treating hepatitis b and its preparation method and application thereof

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Application Number Priority Date Filing Date Title
CN202110374234.2A CN114107393A (zh) 2021-04-07 2021-04-07 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用

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CN114107393A true CN114107393A (zh) 2022-03-01

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CN202110374234.2A Pending CN114107393A (zh) 2021-04-07 2021-04-07 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用
CN202210359887.8A Active CN115197969B (zh) 2021-04-07 2022-04-06 一种治疗乙型肝炎的慢病毒载体、慢病毒颗粒及其制备方法和应用

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US (1) US20250073332A1 (https=)
EP (1) EP4319805A1 (https=)
JP (1) JP2024516115A (https=)
KR (1) KR20240004429A (https=)
CN (2) CN114107393A (https=)
AU (1) AU2022255056A1 (https=)
BR (1) BR112023020732A2 (https=)
CA (1) CA3214383A1 (https=)
TW (1) TWI906499B (https=)
WO (1) WO2022214599A1 (https=)
ZA (1) ZA202309368B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024159517A1 (zh) * 2023-02-03 2024-08-08 南方科技大学 一种乙型肝炎mRNA及其疫苗与用途

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CN1081069C (zh) 1998-08-14 2002-03-20 饶纬华 乙型肝炎治疗性疫苗及其制备方法
US8158413B2 (en) 2005-10-17 2012-04-17 Institut Pasteur Lentiviral vector-based vaccine
WO2008103380A2 (en) * 2007-02-21 2008-08-28 Fox Chase Cancer Center Hepatitis b virus compositions and methods of use
DK2185192T3 (en) 2007-08-03 2019-02-18 Pasteur Institut LENTIVIRAL TRANSFER VECTORS AND THEIR MEDICAL USES
CN101502650B (zh) * 2009-03-10 2011-12-28 邢益平 密码子优化的乙型肝炎核酸疫苗
EP2666477A1 (en) 2012-05-23 2013-11-27 Theravectys Lentiviral vectors containing an MHC class I promoter
CA2849652C (en) 2011-09-26 2017-11-21 Theravectys Use of non-subtype b gag proteins for lentiviral packaging
RS61118B1 (sr) * 2016-01-12 2020-12-31 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh Sredstva i postupci za lečenje hbv
EP3276006A1 (en) * 2016-07-27 2018-01-31 Theravectys Lentiviral vectors for expression of hepatitis b virus (hbv) antigens
EP3532084A4 (en) * 2016-10-31 2020-05-27 Georgia State University Research Foundation, Inc. VIRUS-LIKE HEPATITIS-B-VIRUS-PRÄ-S-PROTEIN PARTICLE
CN106928372B (zh) * 2016-12-30 2019-09-13 北京大学深圳研究生院 乙肝重组抗原及其表达基因、构建方法、病毒样颗粒及其制备方法、应用与疫苗
CN107058346B (zh) * 2017-05-03 2021-01-29 李军涛 一种乙肝病毒表面抗原基因与表达载体及细胞株
CA3132601A1 (en) * 2019-03-05 2020-09-10 Glaxosmithkline Biologicals Sa Hepatitis b immunisation regimen and compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024159517A1 (zh) * 2023-02-03 2024-08-08 南方科技大学 一种乙型肝炎mRNA及其疫苗与用途

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EP4319805A1 (en) 2024-02-14
KR20240004429A (ko) 2024-01-11
TWI906499B (zh) 2025-12-01
AU2022255056A1 (en) 2023-10-26
CN115197969B (zh) 2023-09-01
WO2022214599A1 (en) 2022-10-13
ZA202309368B (en) 2025-03-26
CA3214383A1 (en) 2022-10-13
BR112023020732A2 (pt) 2024-01-09
TW202239963A (zh) 2022-10-16
US20250073332A1 (en) 2025-03-06
JP2024516115A (ja) 2024-04-12
CN115197969A (zh) 2022-10-18

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