KR20230171936A - 지속 작용성 성장 호르몬 폴리펩타이드를 투여하는 방법 - Google Patents
지속 작용성 성장 호르몬 폴리펩타이드를 투여하는 방법 Download PDFInfo
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- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
- 238000011285 therapeutic regimen Methods 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 229940034208 thyroxine Drugs 0.000 description 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000012049 topical pharmaceutical composition Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 108010015666 tryptophyl-leucyl-glutamic acid Proteins 0.000 description 1
- 238000011870 unpaired t-test Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 108010009962 valyltyrosine Proteins 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000004034 viscosity adjusting agent Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163163504P | 2021-03-19 | 2021-03-19 | |
| US63/163,504 | 2021-03-19 | ||
| US202163272417P | 2021-10-27 | 2021-10-27 | |
| US63/272,417 | 2021-10-27 | ||
| PCT/US2022/020804 WO2022197961A1 (en) | 2021-03-19 | 2022-03-17 | Methods of administering long-acting growth hormone polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20230171936A true KR20230171936A (ko) | 2023-12-21 |
Family
ID=83320806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237035239A Pending KR20230171936A (ko) | 2021-03-19 | 2022-03-17 | 지속 작용성 성장 호르몬 폴리펩타이드를 투여하는 방법 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240166710A1 (https=) |
| EP (1) | EP4308151A4 (https=) |
| JP (1) | JP2022145646A (https=) |
| KR (1) | KR20230171936A (https=) |
| AU (1) | AU2022238386A1 (https=) |
| BR (1) | BR112023018980A2 (https=) |
| CA (1) | CA3214273A1 (https=) |
| IL (1) | IL305661A (https=) |
| MX (1) | MX2023010997A (https=) |
| WO (1) | WO2022197961A1 (https=) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020155990A1 (en) * | 2001-04-20 | 2002-10-24 | Renasci, Inc., D/B/A Renasci Anti-Aging Center | Method of optimizing growth hormone replacement |
| WO2009102734A1 (en) * | 2008-02-11 | 2009-08-20 | Depomed Inc. | Methods for treating vasomotor symptoms using gaba analogs in a gastric retentive dosage form |
| US20150158926A1 (en) * | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
| RU2746943C2 (ru) * | 2013-10-21 | 2021-04-22 | Опко Байолоджикс Лтд. | Полипептиды длительного действия и способы их получения и введения |
| DK3220892T3 (da) * | 2014-11-21 | 2021-11-08 | Ascendis Pharma Endocrinology Div A/S | Langtidsvirkende væksthormondoseringsformer |
| HRP20230405T8 (hr) * | 2014-12-10 | 2023-09-29 | Opko Biologics Ltd. | Metode proizvodnje dugo djelujućih ctp-modificiranih polipeptida hormona rasta |
| JP7000153B2 (ja) * | 2014-12-10 | 2022-01-19 | オプコ バイオロジクス リミテッド | 長時間作用性ｃｔｐ修飾成長ホルモンポリペプチドを生成する方法 |
-
2022
- 2022-03-17 MX MX2023010997A patent/MX2023010997A/es unknown
- 2022-03-17 BR BR112023018980A patent/BR112023018980A2/pt unknown
- 2022-03-17 CA CA3214273A patent/CA3214273A1/en active Pending
- 2022-03-17 AU AU2022238386A patent/AU2022238386A1/en active Pending
- 2022-03-17 KR KR1020237035239A patent/KR20230171936A/ko active Pending
- 2022-03-17 EP EP22772229.5A patent/EP4308151A4/en active Pending
- 2022-03-17 JP JP2022042639A patent/JP2022145646A/ja active Pending
- 2022-03-17 IL IL305661A patent/IL305661A/en unknown
- 2022-03-17 US US18/282,844 patent/US20240166710A1/en active Pending
- 2022-03-17 WO PCT/US2022/020804 patent/WO2022197961A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA3214273A1 (en) | 2022-09-22 |
| MX2023010997A (es) | 2023-11-28 |
| JP2022145646A (ja) | 2022-10-04 |
| EP4308151A1 (en) | 2024-01-24 |
| WO2022197961A1 (en) | 2022-09-22 |
| BR112023018980A2 (pt) | 2023-12-05 |
| AU2022238386A1 (en) | 2023-09-14 |
| US20240166710A1 (en) | 2024-05-23 |
| IL305661A (en) | 2023-11-01 |
| EP4308151A4 (en) | 2025-02-26 |
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| PA0105 | International application |
Patent event date: 20231016 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PA0201 | Request for examination |
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