BR112023018980A2 - Métodos de administração de polipeptídeos de hormônio de crescimento de ação prolongada - Google Patents

Métodos de administração de polipeptídeos de hormônio de crescimento de ação prolongada

Info

Publication number
BR112023018980A2
BR112023018980A2 BR112023018980A BR112023018980A BR112023018980A2 BR 112023018980 A2 BR112023018980 A2 BR 112023018980A2 BR 112023018980 A BR112023018980 A BR 112023018980A BR 112023018980 A BR112023018980 A BR 112023018980A BR 112023018980 A2 BR112023018980 A2 BR 112023018980A2
Authority
BR
Brazil
Prior art keywords
growth hormone
long
methods
administration
acting
Prior art date
Application number
BR112023018980A
Other languages
English (en)
Portuguese (pt)
Inventor
Aleksandra Pastrak
Francisco Cara Jóse
Paul Wajnrajch Michael
Rao Valluri Srinivas
Original Assignee
Opko Biologics Ltd
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opko Biologics Ltd, Pfizer filed Critical Opko Biologics Ltd
Publication of BR112023018980A2 publication Critical patent/BR112023018980A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/65Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR112023018980A 2021-03-19 2022-03-17 Métodos de administração de polipeptídeos de hormônio de crescimento de ação prolongada BR112023018980A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163163504P 2021-03-19 2021-03-19
US202163272417P 2021-10-27 2021-10-27
PCT/US2022/020804 WO2022197961A1 (en) 2021-03-19 2022-03-17 Methods of administering long-acting growth hormone polypeptides

Publications (1)

Publication Number Publication Date
BR112023018980A2 true BR112023018980A2 (pt) 2023-12-05

Family

ID=83320806

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023018980A BR112023018980A2 (pt) 2021-03-19 2022-03-17 Métodos de administração de polipeptídeos de hormônio de crescimento de ação prolongada

Country Status (10)

Country Link
US (1) US20240166710A1 (https=)
EP (1) EP4308151A4 (https=)
JP (1) JP2022145646A (https=)
KR (1) KR20230171936A (https=)
AU (1) AU2022238386A1 (https=)
BR (1) BR112023018980A2 (https=)
CA (1) CA3214273A1 (https=)
IL (1) IL305661A (https=)
MX (1) MX2023010997A (https=)
WO (1) WO2022197961A1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020155990A1 (en) * 2001-04-20 2002-10-24 Renasci, Inc., D/B/A Renasci Anti-Aging Center Method of optimizing growth hormone replacement
WO2009102734A1 (en) * 2008-02-11 2009-08-20 Depomed Inc. Methods for treating vasomotor symptoms using gaba analogs in a gastric retentive dosage form
US20150158926A1 (en) * 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
RU2746943C2 (ru) * 2013-10-21 2021-04-22 Опко Байолоджикс Лтд. Полипептиды длительного действия и способы их получения и введения
DK3220892T3 (da) * 2014-11-21 2021-11-08 Ascendis Pharma Endocrinology Div A/S Langtidsvirkende væksthormondoseringsformer
HRP20230405T8 (hr) * 2014-12-10 2023-09-29 Opko Biologics Ltd. Metode proizvodnje dugo djelujućih ctp-modificiranih polipeptida hormona rasta
JP7000153B2 (ja) * 2014-12-10 2022-01-19 オプコ バイオロジクス リミテッド 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法

Also Published As

Publication number Publication date
CA3214273A1 (en) 2022-09-22
MX2023010997A (es) 2023-11-28
JP2022145646A (ja) 2022-10-04
EP4308151A1 (en) 2024-01-24
WO2022197961A1 (en) 2022-09-22
AU2022238386A1 (en) 2023-09-14
US20240166710A1 (en) 2024-05-23
IL305661A (en) 2023-11-01
EP4308151A4 (en) 2025-02-26
KR20230171936A (ko) 2023-12-21

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