KR20230147136A - Raf 억제제와 mek 억제제의 조합 - Google Patents
Raf 억제제와 mek 억제제의 조합 Download PDFInfo
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- KR20230147136A KR20230147136A KR1020237031421A KR20237031421A KR20230147136A KR 20230147136 A KR20230147136 A KR 20230147136A KR 1020237031421 A KR1020237031421 A KR 1020237031421A KR 20237031421 A KR20237031421 A KR 20237031421A KR 20230147136 A KR20230147136 A KR 20230147136A
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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| US63/173,158 | 2021-04-09 | ||
| PCT/US2022/016962 WO2022178244A1 (en) | 2021-02-19 | 2022-02-18 | Combination of raf inhibitor and mek inhibitor |
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| WO2025106686A1 (en) * | 2023-11-15 | 2025-05-22 | Day One Biopharmaceuticals, Inc. | Methods of treating pediatric low-grade glioma |
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| CN104428001A (zh) * | 2012-03-30 | 2015-03-18 | 武田药品工业有限公司 | Raf抑制剂和mek抑制剂在黑素瘤治疗中的投与 |
| CA3240745A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Cancer treatment using combinations of erk and raf inhibitors |
| UY36046A (es) * | 2014-03-26 | 2015-10-30 | Millennium Pharm Inc | Formulaciones farmacéuticas, procesos para la preparación y métodos de uso |
| WO2016025648A1 (en) * | 2014-08-13 | 2016-02-18 | Celgene Avilomics Research, Inc. | Combinations of an erk inhibitor and a raf inhibitor and related methods |
| AU2018329925B2 (en) * | 2017-09-08 | 2025-05-29 | F. Hoffmann-La Roche Ag | Diagnostic and therapeutic methods for cancer |
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| EP4294400A1 (en) | 2023-12-27 |
| WO2022178244A1 (en) | 2022-08-25 |
| MX2023009642A (es) | 2023-10-16 |
| EP4294400A4 (en) | 2025-01-01 |
| US20240058338A1 (en) | 2024-02-22 |
| AU2022223437A1 (en) | 2023-09-07 |
| IL305250A (en) | 2023-10-01 |
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| JP2024507221A (ja) | 2024-02-16 |
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