KR20230142774A - 화학적으로 변형된 작은 활성화 rna - Google Patents
화학적으로 변형된 작은 활성화 rna Download PDFInfo
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- KR20230142774A KR20230142774A KR1020237030334A KR20237030334A KR20230142774A KR 20230142774 A KR20230142774 A KR 20230142774A KR 1020237030334 A KR1020237030334 A KR 1020237030334A KR 20237030334 A KR20237030334 A KR 20237030334A KR 20230142774 A KR20230142774 A KR 20230142774A
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- rag1
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- oligonucleotide strand
- small activating
- rna
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| CNPCT/CN2021/075958 | 2021-02-08 | ||
| PCT/CN2022/074635 WO2022166814A1 (zh) | 2021-02-07 | 2022-01-28 | 一种化学修饰的小激活rna |
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| WO2025224036A1 (en) * | 2024-04-22 | 2025-10-30 | Mina Therapeutics Limited | Chemically modified sarna compositions and methods of use |
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| EP1871426B1 (en) * | 2005-04-15 | 2017-06-07 | The Regents of The University of California | Small activating rna molecules and their use |
| US9045751B2 (en) * | 2010-04-28 | 2015-06-02 | The Regents Of The University Of California | Modified small activating RNA molecules and methods of use |
| WO2014152211A1 (en) | 2013-03-14 | 2014-09-25 | Moderna Therapeutics, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
| SI3071696T1 (sl) * | 2013-11-22 | 2019-11-29 | Mina Therapeutics Ltd | C/EBP alfa kratko delujoči RNA sestavki in postopki uporabe |
| KR102599712B1 (ko) * | 2015-04-22 | 2023-11-09 | 미나 테라퓨틱스 리미티드 | C/EBP 알파 saRNA 조성물 및 사용 방법 |
| CN109563511A (zh) | 2016-06-30 | 2019-04-02 | 阿布特斯生物制药公司 | 用于递送信使rna的组合物和方法 |
| US11583504B2 (en) | 2016-11-08 | 2023-02-21 | Modernatx, Inc. | Stabilized formulations of lipid nanoparticles |
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| US20210332366A1 (en) * | 2018-04-10 | 2021-10-28 | Ractigen Therapeutics | Novel Small Activating RNA |
| WO2019196883A1 (zh) * | 2018-04-10 | 2019-10-17 | 中美瑞康核酸技术(南通)研究院有限公司 | 一种激活p21基因表达的方法 |
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| EP4289952A1 (en) | 2023-12-13 |
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