KR20230120134A - 폴리펩티드 및 이의 용도 - Google Patents

폴리펩티드 및 이의 용도 Download PDF

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Publication number
KR20230120134A
KR20230120134A KR1020237023385A KR20237023385A KR20230120134A KR 20230120134 A KR20230120134 A KR 20230120134A KR 1020237023385 A KR1020237023385 A KR 1020237023385A KR 20237023385 A KR20237023385 A KR 20237023385A KR 20230120134 A KR20230120134 A KR 20230120134A
Authority
KR
South Korea
Prior art keywords
xaa
aib
diacid
amide
cntatc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237023385A
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English (en)
Korean (ko)
Inventor
마리아 알렉산드라 베드나렉
시바네스와리 제나파시
Original Assignee
메디뮨 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 메디뮨 리미티드 filed Critical 메디뮨 리미티드
Publication of KR20230120134A publication Critical patent/KR20230120134A/ko
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020237023385A 2020-12-16 2021-12-15 폴리펩티드 및 이의 용도 Pending KR20230120134A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063125996P 2020-12-16 2020-12-16
US63/125,996 2020-12-16
PCT/EP2021/086034 WO2022129254A1 (en) 2020-12-16 2021-12-15 Polypeptides and uses thereof

Publications (1)

Publication Number Publication Date
KR20230120134A true KR20230120134A (ko) 2023-08-16

Family

ID=79287870

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237023385A Pending KR20230120134A (ko) 2020-12-16 2021-12-15 폴리펩티드 및 이의 용도

Country Status (16)

Country Link
US (3) US20240067693A1 (https=)
EP (1) EP4263586B1 (https=)
JP (2) JP7767428B2 (https=)
KR (1) KR20230120134A (https=)
CN (1) CN116685599A (https=)
AR (1) AR124391A1 (https=)
AU (2) AU2021399076B2 (https=)
CA (1) CA3204296A1 (https=)
CL (1) CL2023001719A1 (https=)
CO (1) CO2023009066A2 (https=)
CR (1) CR20230311A (https=)
EC (1) ECSP23052600A (https=)
IL (1) IL303578A (https=)
MX (1) MX2023007288A (https=)
TW (1) TW202241933A (https=)
WO (1) WO2022129254A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240067693A1 (en) 2020-12-16 2024-02-29 Medimmune Limited Polypeptides and uses thereof
WO2022159395A1 (en) 2021-01-20 2022-07-28 Viking Therapeutics, Inc. Compositions and methods for the treatment of metabolic and liver disorders
MX2024003236A (es) 2021-09-15 2024-06-19 Viking Therapeutics Inc Composiciones y metodos para el tratamiento de trastornos metabolicos y hepaticos.
US12116388B2 (en) 2022-12-22 2024-10-15 Novo Nordisk A/S Amylin receptor agonists
AU2024218747A1 (en) * 2023-02-10 2025-08-28 Hangzhou Sciwind Biosciences Co., Ltd. Polypeptide and derivative thereof, composition, and use thereof
JP7755031B2 (ja) 2023-11-30 2025-10-15 ノヴォ ノルディスク アー/エス Glp-1、gip、およびアミリン受容体の三重作動薬
WO2025147628A2 (en) * 2024-01-05 2025-07-10 Indiana University Research And Technology Corporation Dual amylin calcitonin receptor agonists
WO2025242620A1 (en) 2024-05-20 2025-11-27 Medimmune Limited Polypeptide combinations and uses thereof
WO2026058194A1 (en) 2024-09-12 2026-03-19 Medimmune Limited Polypeptide dosage regimens

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004051014A1 (de) 2004-10-20 2006-04-27 Rwth Aachen Chemisch modifizierte Peptidanaloga
JP5252435B2 (ja) 2006-03-15 2013-07-31 ノボ・ノルデイスク・エー/エス アミリン誘導体
EP2036923A1 (en) 2007-09-11 2009-03-18 Novo Nordisk A/S Improved derivates of amylin
CN102197049B (zh) * 2008-10-21 2015-03-25 诺沃-诺迪斯克有限公司 胰岛淀粉样多肽衍生物
US9205135B2 (en) * 2009-09-22 2015-12-08 University Of Miami Podocyte pH modulation and uses thereof
US20140249076A1 (en) 2011-10-18 2014-09-04 Astrazeneca Pharmaceuticals Lp Amylin-calcitonin chimeric peptides conjugated to duration enhancing moieties
SG10201805039UA (en) * 2013-12-13 2018-07-30 Medimmune Ltd Protease resistant peptides
JP6730278B2 (ja) 2014-11-27 2020-07-29 ノヴォ ノルディスク アー/エス Glp−1誘導体及びその使用
AR116632A1 (es) 2018-10-11 2021-05-26 Intarcia Therapeutics Inc Polipéptidos análogos de la amilina humana y sus métodos de uso
WO2020225781A1 (en) 2019-05-08 2020-11-12 Auckland Uniservices Limited Peptide conjugate amylin agonists and uses thereof
US20240067693A1 (en) 2020-12-16 2024-02-29 Medimmune Limited Polypeptides and uses thereof

Also Published As

Publication number Publication date
CR20230311A (es) 2023-09-01
IL303578A (en) 2023-08-01
MX2023007288A (es) 2023-07-03
CO2023009066A2 (es) 2023-07-10
AU2021399076A1 (en) 2023-07-27
CN116685599A (zh) 2023-09-01
CL2023001719A1 (es) 2024-01-26
AU2024227071A1 (en) 2024-10-24
US20240067693A1 (en) 2024-02-29
EP4263586A1 (en) 2023-10-25
WO2022129254A1 (en) 2022-06-23
EP4263586B1 (en) 2026-03-11
AR124391A1 (es) 2023-03-22
JP2023554046A (ja) 2023-12-26
US20220204580A1 (en) 2022-06-30
CA3204296A1 (en) 2022-06-23
TW202241933A (zh) 2022-11-01
AU2021399076A9 (en) 2024-07-18
JP2026031965A (ja) 2026-02-25
AU2021399076B2 (en) 2024-07-11
US12371464B2 (en) 2025-07-29
US20250289860A1 (en) 2025-09-18
JP7767428B2 (ja) 2025-11-11
ECSP23052600A (es) 2023-08-31

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PA0105 International application

Patent event date: 20230710

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20241213

Comment text: Request for Examination of Application