KR20230118142A - 심부전 치료용 rxfp1 조절제로서의 4-(2-플루오로-4-메톡시-5-3-(((1-메틸시클로부틸)메틸)카바모일)바이시클로[2.2.1]헵탄-2-일)카바모일)페녹시)-1-메틸시클로헥산-1-카복실산유도체 및 유사 화합물 - Google Patents

심부전 치료용 rxfp1 조절제로서의 4-(2-플루오로-4-메톡시-5-3-(((1-메틸시클로부틸)메틸)카바모일)바이시클로[2.2.1]헵탄-2-일)카바모일)페녹시)-1-메틸시클로헥산-1-카복실산유도체 및 유사 화합물 Download PDF

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KR20230118142A
KR20230118142A KR1020237022785A KR20237022785A KR20230118142A KR 20230118142 A KR20230118142 A KR 20230118142A KR 1020237022785 A KR1020237022785 A KR 1020237022785A KR 20237022785 A KR20237022785 A KR 20237022785A KR 20230118142 A KR20230118142 A KR 20230118142A
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carbamoyl
fluoro
carboxylic acid
bicyclo
methoxy
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케네스 라르스 그란버그
줄리아 버곤지니
한스 프레드릭 버그스트룀
스티그 요나스 보스트룀
헨릭 그라덴
라르스 요한 안드레아스 울란더
시게키 사카마키
류이치 후치가미
야수키 니와
마사카주 후지오
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아스트라제네카 아베
미쓰비시 타나베 파마 코퍼레이션
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Publication of KR20230118142A publication Critical patent/KR20230118142A/ko
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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020237022785A 2020-12-08 2021-12-07 심부전 치료용 rxfp1 조절제로서의 4-(2-플루오로-4-메톡시-5-3-(((1-메틸시클로부틸)메틸)카바모일)바이시클로[2.2.1]헵탄-2-일)카바모일)페녹시)-1-메틸시클로헥산-1-카복실산유도체 및 유사 화합물 Pending KR20230118142A (ko)

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US20250221966A1 (en) * 2021-10-29 2025-07-10 Bristol-Myers Squibb Company Rxfp1 agonists
US20250268903A1 (en) * 2021-10-29 2025-08-28 Bristol-Myers Squibb Company Rxfp1 agonists
KR20240095290A (ko) * 2021-10-29 2024-06-25 브리스톨-마이어스 스큅 컴퍼니 심부전의 치료를 위한 rxfp1 조정제
ES3062200T3 (en) * 2021-10-29 2026-04-09 Bristol Myers Squibb Co Rxfp1 agonists
US20260069558A1 (en) * 2022-06-07 2026-03-12 Astrazeneca Ab Rxfp1 modulators for treating resistant hypertension or heart failure with pulmonary hypertension
CN119630638A (zh) * 2022-06-07 2025-03-14 阿斯利康(瑞典)有限公司 Rxfp1调节剂的固体形式
US20260069559A1 (en) * 2022-06-07 2026-03-12 Astrazeneca Ab Combinations of rxfp1 modulators and sglt2 inhibitors
CN121605099A (zh) * 2023-08-10 2026-03-03 深圳信立泰药业股份有限公司 一种rxfp1受体调节剂及其制备方法和医药用途
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