KR20230116865A - 우울증의 치료를 위한 nr2b-nmda 수용체 nam의 투여요법 - Google Patents
우울증의 치료를 위한 nr2b-nmda 수용체 nam의 투여요법 Download PDFInfo
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- KR20230116865A KR20230116865A KR1020237021993A KR20237021993A KR20230116865A KR 20230116865 A KR20230116865 A KR 20230116865A KR 1020237021993 A KR1020237021993 A KR 1020237021993A KR 20237021993 A KR20237021993 A KR 20237021993A KR 20230116865 A KR20230116865 A KR 20230116865A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063121513P | 2020-12-04 | 2020-12-04 | |
| US202063121508P | 2020-12-04 | 2020-12-04 | |
| US63/121,513 | 2020-12-04 | ||
| US63/121,508 | 2020-12-04 | ||
| PCT/IB2021/061268 WO2022118264A1 (en) | 2020-12-04 | 2021-12-03 | Dosage regimen for a nr2b-nmda receptor nam for the treatment of depression |
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| KR20230116865A true KR20230116865A (ko) | 2023-08-04 |
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| KR1020237021993A Pending KR20230116865A (ko) | 2020-12-04 | 2021-12-03 | 우울증의 치료를 위한 nr2b-nmda 수용체 nam의 투여요법 |
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| US (1) | US20240041853A1 (https=) |
| EP (1) | EP4255419A1 (https=) |
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| TW (1) | TW202237103A (https=) |
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| CA3258070A1 (en) * | 2022-06-02 | 2023-12-07 | Novartis Ag | SUBCUTANEOUS ADMINISTRATION OF ONFASPRODIL AND DOSING METHODS INTENDED FOR USE IN THE TREATMENT OF DEPRESSIVE DISORDERS |
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| IL145584A0 (en) * | 2000-10-02 | 2002-06-30 | Pfizer Prod Inc | Nmda nr2b antagonists for treatment |
| AR097794A1 (es) * | 2013-09-26 | 2016-04-13 | Mnemosyne Pharmaceuticals Inc | Moduladores octahidro-ciclopenta[c]pirrol negativos de nr2b |
| JO3579B1 (ar) * | 2014-09-26 | 2020-07-05 | Luc Therapeutics Inc | مُعدِلات تفاغرية سالبة لمستقبل nr2b من المركب n-ألكيل أريل-5-أوكسي أريل-ثامن هيدرو-خماسي الحلقة [c] بيرول |
| US10202363B2 (en) * | 2014-12-23 | 2019-02-12 | Cerecor, Inc. | Compounds, compositions and methods |
| BR112018007181A2 (pt) * | 2015-10-14 | 2018-10-16 | Bristol-Myers Squibb Company | antagonistas de nr2b seletivos |
| KR20180063306A (ko) * | 2015-10-14 | 2018-06-11 | 브리스톨-마이어스 스큅 컴퍼니 | 선택적 nr2b 길항제 |
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