IL303357A - Dosage regimen for a nr2b-nmda receptor nam for the treatment of depression - Google Patents

Dosage regimen for a nr2b-nmda receptor nam for the treatment of depression

Info

Publication number
IL303357A
IL303357A IL303357A IL30335723A IL303357A IL 303357 A IL303357 A IL 303357A IL 303357 A IL303357 A IL 303357A IL 30335723 A IL30335723 A IL 30335723A IL 303357 A IL303357 A IL 303357A
Authority
IL
Israel
Prior art keywords
compound
pharmaceutically acceptable
acceptable salt
treatment
patient
Prior art date
Application number
IL303357A
Other languages
English (en)
Hebrew (he)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL303357A publication Critical patent/IL303357A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL303357A 2020-12-04 2021-12-03 Dosage regimen for a nr2b-nmda receptor nam for the treatment of depression IL303357A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063121513P 2020-12-04 2020-12-04
US202063121508P 2020-12-04 2020-12-04
PCT/IB2021/061268 WO2022118264A1 (en) 2020-12-04 2021-12-03 Dosage regimen for a nr2b-nmda receptor nam for the treatment of depression

Publications (1)

Publication Number Publication Date
IL303357A true IL303357A (en) 2023-08-01

Family

ID=78844691

Family Applications (1)

Application Number Title Priority Date Filing Date
IL303357A IL303357A (en) 2020-12-04 2021-12-03 Dosage regimen for a nr2b-nmda receptor nam for the treatment of depression

Country Status (10)

Country Link
US (1) US20240041853A1 (https=)
EP (1) EP4255419A1 (https=)
JP (1) JP2023551943A (https=)
KR (1) KR20230116865A (https=)
AU (1) AU2021390209A1 (https=)
CA (1) CA3203144A1 (https=)
IL (1) IL303357A (https=)
MX (1) MX2023006567A (https=)
TW (1) TW202237103A (https=)
WO (1) WO2022118264A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3258070A1 (en) * 2022-06-02 2023-12-07 Novartis Ag SUBCUTANEOUS ADMINISTRATION OF ONFASPRODIL AND DOSING METHODS INTENDED FOR USE IN THE TREATMENT OF DEPRESSIVE DISORDERS
TW202539663A (zh) * 2023-12-06 2025-10-16 瑞士商諾華公司 用於治療抑鬱障礙之組成物和方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL145584A0 (en) * 2000-10-02 2002-06-30 Pfizer Prod Inc Nmda nr2b antagonists for treatment
AR097794A1 (es) * 2013-09-26 2016-04-13 Mnemosyne Pharmaceuticals Inc Moduladores octahidro-ciclopenta[c]pirrol negativos de nr2b
JO3579B1 (ar) * 2014-09-26 2020-07-05 Luc Therapeutics Inc مُعدِلات تفاغرية سالبة لمستقبل nr2b من المركب n-ألكيل أريل-5-أوكسي أريل-ثامن هيدرو-خماسي الحلقة [c] بيرول
US10202363B2 (en) * 2014-12-23 2019-02-12 Cerecor, Inc. Compounds, compositions and methods
BR112018007181A2 (pt) * 2015-10-14 2018-10-16 Bristol-Myers Squibb Company antagonistas de nr2b seletivos
KR20180063306A (ko) * 2015-10-14 2018-06-11 브리스톨-마이어스 스큅 컴퍼니 선택적 nr2b 길항제

Also Published As

Publication number Publication date
MX2023006567A (es) 2023-06-16
US20240041853A1 (en) 2024-02-08
CA3203144A1 (en) 2022-06-09
KR20230116865A (ko) 2023-08-04
AU2021390209A9 (en) 2024-10-31
JP2023551943A (ja) 2023-12-13
TW202237103A (zh) 2022-10-01
EP4255419A1 (en) 2023-10-11
WO2022118264A1 (en) 2022-06-09
AU2021390209A1 (en) 2023-06-22

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