KR20230088810A - 마이크로rna-29 화합물, 조성물 및 요법에서의 용도 - Google Patents

마이크로rna-29 화합물, 조성물 및 요법에서의 용도 Download PDF

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KR20230088810A
KR20230088810A KR1020237016847A KR20237016847A KR20230088810A KR 20230088810 A KR20230088810 A KR 20230088810A KR 1020237016847 A KR1020237016847 A KR 1020237016847A KR 20237016847 A KR20237016847 A KR 20237016847A KR 20230088810 A KR20230088810 A KR 20230088810A
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mir
compound
salt
dose
cwt
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데렉 스튜어트 길크리스트
닐 린제이 밀러
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커즈웨이 테라퓨틱스 리미티드
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    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
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    • C12N2310/32Chemical structure of the sugar
    • C12N2310/3212'-O-R Modification
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
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    • C12N2310/3515Lipophilic moiety, e.g. cholesterol
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    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/35Special therapeutic applications based on a specific dosage / administration regimen

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KR1020237016847A 2020-10-23 2021-10-25 마이크로rna-29 화합물, 조성물 및 요법에서의 용도 Pending KR20230088810A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2016863.9A GB202016863D0 (en) 2020-10-23 2020-10-23 Microrna-29 compounds, compositions and uses in therapy
GB2016863.9 2020-10-23
PCT/EP2021/079580 WO2022084561A2 (en) 2020-10-23 2021-10-25 Microrna-29 compounds, compositions and uses in therapy

Publications (1)

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KR20230088810A true KR20230088810A (ko) 2023-06-20

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KR1020237016847A Pending KR20230088810A (ko) 2020-10-23 2021-10-25 마이크로rna-29 화합물, 조성물 및 요법에서의 용도

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Country Link
US (1) US20240390410A1 (https=)
EP (1) EP4232580A2 (https=)
JP (1) JP2023547274A (https=)
KR (1) KR20230088810A (https=)
CN (1) CN116744942A (https=)
AU (1) AU2021365394A1 (https=)
CA (1) CA3195977A1 (https=)
GB (1) GB202016863D0 (https=)
WO (1) WO2022084561A2 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023445724A1 (en) * 2023-04-28 2025-11-06 Causeway Therapeutics Limited Microrna-29 compounds, compositions and uses in therapy, and methods for evaluating tendinopathic lesions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201400598D0 (en) * 2014-01-14 2014-03-05 Univ Glasgow Materials and methods for modulation of tendon healing
CA2949109A1 (en) * 2014-05-29 2015-12-03 Quark Pharmaceuticals, Inc. Methods and compositions for preventing ischemia reperfusion injury in organs
US9376681B2 (en) * 2014-09-08 2016-06-28 MiRagen Therapeutics, Inc. miR-29 mimics and uses thereof
GB201503967D0 (en) * 2015-03-09 2015-04-22 Univ Glasgow Biocompatible implants for use in tendon therapy
US20200318113A1 (en) * 2019-03-05 2020-10-08 MiRagen Therapeutics, Inc. Polynucleotide conjugates and uses thereof

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Publication number Publication date
EP4232580A2 (en) 2023-08-30
CA3195977A1 (en) 2022-04-28
US20240390410A1 (en) 2024-11-28
WO2022084561A3 (en) 2022-06-02
AU2021365394A1 (en) 2023-06-08
JP2023547274A (ja) 2023-11-09
WO2022084561A2 (en) 2022-04-28
CN116744942A (zh) 2023-09-12
GB202016863D0 (en) 2020-12-09

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