KR20230047328A - 시간 계측 장치, 형광 수명 계측 장치, 및 시간 계측 방법 - Google Patents
시간 계측 장치, 형광 수명 계측 장치, 및 시간 계측 방법 Download PDFInfo
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- KR20230047328A KR20230047328A KR1020227044160A KR20227044160A KR20230047328A KR 20230047328 A KR20230047328 A KR 20230047328A KR 1020227044160 A KR1020227044160 A KR 1020227044160A KR 20227044160 A KR20227044160 A KR 20227044160A KR 20230047328 A KR20230047328 A KR 20230047328A
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- time
- signal
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- detection signal
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- 238000005259 measurement Methods 0.000 title claims abstract description 196
- 238000000691 measurement method Methods 0.000 title claims description 7
- 238000001514 detection method Methods 0.000 claims abstract description 94
- 238000000034 method Methods 0.000 claims description 19
- 230000001360 synchronised effect Effects 0.000 claims description 6
- 230000001678 irradiating effect Effects 0.000 claims description 3
- 239000000523 sample Substances 0.000 description 19
- 238000010586 diagram Methods 0.000 description 10
- 230000005284 excitation Effects 0.000 description 8
- 101000831616 Homo sapiens Protachykinin-1 Proteins 0.000 description 6
- 102100024304 Protachykinin-1 Human genes 0.000 description 6
- 101100243108 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) PDI1 gene Proteins 0.000 description 5
- 238000009795 derivation Methods 0.000 description 5
- 230000006866 deterioration Effects 0.000 description 5
- 238000001917 fluorescence detection Methods 0.000 description 4
- 101000655188 Homo sapiens Tachykinin-3 Proteins 0.000 description 3
- 102100033009 Tachykinin-3 Human genes 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000002189 fluorescence spectrum Methods 0.000 description 2
- 230000002238 attenuated effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 230000005283 ground state Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Images
Classifications
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- G—PHYSICS
- G04—HOROLOGY
- G04F—TIME-INTERVAL MEASURING
- G04F10/00—Apparatus for measuring unknown time intervals by electric means
- G04F10/005—Time-to-digital converters [TDC]
-
- G—PHYSICS
- G04—HOROLOGY
- G04F—TIME-INTERVAL MEASURING
- G04F10/00—Apparatus for measuring unknown time intervals by electric means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G04—HOROLOGY
- G04F—TIME-INTERVAL MEASURING
- G04F10/00—Apparatus for measuring unknown time intervals by electric means
- G04F10/10—Apparatus for measuring unknown time intervals by electric means by measuring electric or magnetic quantities changing in proportion to time
- G04F10/105—Apparatus for measuring unknown time intervals by electric means by measuring electric or magnetic quantities changing in proportion to time with conversion of the time-intervals
-
- G—PHYSICS
- G04—HOROLOGY
- G04F—TIME-INTERVAL MEASURING
- G04F13/00—Apparatus for measuring unknown time intervals by means not provided for in groups G04F5/00 - G04F10/00
- G04F13/02—Apparatus for measuring unknown time intervals by means not provided for in groups G04F5/00 - G04F10/00 using optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
- G01N2021/6415—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence with two excitations, e.g. strong pump/probe flash
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/123—Conversion circuit
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measurement Of Unknown Time Intervals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPJP-P-2020-133839 | 2020-08-06 | ||
| JP2020133839 | 2020-08-06 | ||
| PCT/JP2021/018263 WO2022030062A1 (ja) | 2020-08-06 | 2021-05-13 | 時間計測装置、蛍光寿命計測装置、及び時間計測方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20230047328A true KR20230047328A (ko) | 2023-04-07 |
Family
ID=77915227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227044160A Withdrawn KR20230047328A (ko) | 2020-08-06 | 2021-05-13 | 시간 계측 장치, 형광 수명 계측 장치, 및 시간 계측 방법 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230288336A1 (enExample) |
| EP (1) | EP4170436A4 (enExample) |
| JP (2) | JP6946599B1 (enExample) |
| KR (1) | KR20230047328A (enExample) |
| CN (1) | CN115803689A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025004353A1 (ja) * | 2023-06-30 | 2025-01-02 | 日本電信電話株式会社 | 測定装置、測定方法、及びプログラム |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003522946A (ja) | 2000-02-10 | 2003-07-29 | エボテック オーアーイー アクチェンゲゼルシャフト | 蛍光強度及び寿命分布分析 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5576919A (en) * | 1978-12-06 | 1980-06-10 | Japan Spectroscopic Co | Measuring method for rapid time division spectroscopic analysis |
| JPS5972049A (ja) * | 1982-10-19 | 1984-04-23 | Horiba Ltd | 試料の発光寿命測定装置 |
| JPS59108261U (ja) * | 1983-01-08 | 1984-07-21 | 株式会社堀場製作所 | 試料の発光寿命測定装置 |
| DE102007026684B4 (de) * | 2007-06-08 | 2009-03-19 | Gesellschaft für Schwerionenforschung mbH | Zeit-Amplituden-Konverter-Bauelement |
| EP2199830B1 (en) * | 2008-12-19 | 2014-07-02 | Leibniz-Institut für Neurobiologie | A position resolved measurement apparatus and a method for acquiring space coordinates of a quantum beam incident thereon |
| JP2010266291A (ja) * | 2009-05-13 | 2010-11-25 | Mitsubishi Electric Corp | 時間計測回路 |
| CN102545669A (zh) * | 2010-12-21 | 2012-07-04 | 台达电子工业股份有限公司 | 具有电容转换功能的太阳能光电系统 |
| CN201926878U (zh) * | 2010-12-23 | 2011-08-10 | 中国科学院西安光学精密机械研究所 | 一种光子序列到达时间的连续测量装置 |
| WO2013034770A2 (en) * | 2011-09-08 | 2013-03-14 | Borowski, André | Time-to-digital converter, 3d imager using same, method for time-to-digital conversion and method for 3d imaging |
| DE102011055330B4 (de) * | 2011-11-14 | 2024-10-31 | Leica Microsystems Cms Gmbh | Verfahren zum Messen der Lebensdauer eines angeregten Zustandes in einer Probe |
| JP5978266B2 (ja) * | 2014-09-03 | 2016-08-24 | 浜松ホトニクス株式会社 | 時間計測装置、時間計測方法、発光寿命計測装置、及び発光寿命計測方法 |
| EP3465156B1 (de) * | 2016-05-25 | 2020-03-18 | Leica Microsystems CMS GmbH | Fluoreszenzlebensdauer-mikroskopieverfahren mit zeitkorrelierter einzelphotonenzählung welches höhere lichtintensitäten zulässt, und entsprechende vorrichtung |
| KR102035019B1 (ko) * | 2017-09-20 | 2019-10-22 | 주식회사 유진로봇 | 거리 측정 장치, 시간 디지털 변환기, 및 이동체 |
| CN110568749B (zh) * | 2019-08-30 | 2021-04-09 | 华中师范大学 | 时间数字转换器电路、装置、设备及装置的控制方法 |
-
2021
- 2021-05-13 EP EP21853056.6A patent/EP4170436A4/en active Pending
- 2021-05-13 CN CN202180046560.9A patent/CN115803689A/zh active Pending
- 2021-05-13 JP JP2021541093A patent/JP6946599B1/ja active Active
- 2021-05-13 US US18/017,698 patent/US20230288336A1/en not_active Abandoned
- 2021-05-13 KR KR1020227044160A patent/KR20230047328A/ko not_active Withdrawn
- 2021-09-15 JP JP2021150175A patent/JP7660049B2/ja active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003522946A (ja) | 2000-02-10 | 2003-07-29 | エボテック オーアーイー アクチェンゲゼルシャフト | 蛍光強度及び寿命分布分析 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7660049B2 (ja) | 2025-04-10 |
| EP4170436A4 (en) | 2024-07-10 |
| JP2022031264A (ja) | 2022-02-18 |
| JP6946599B1 (ja) | 2021-10-06 |
| EP4170436A1 (en) | 2023-04-26 |
| JPWO2022030062A1 (enExample) | 2022-02-10 |
| US20230288336A1 (en) | 2023-09-14 |
| CN115803689A (zh) | 2023-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20221215 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1202 | Submission of document of withdrawal before decision of registration |
Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment) Patent event code: PC12021R01D Patent event date: 20240326 |
|
| WITB | Written withdrawal of application |