JP6946599B1 - 時間計測装置、蛍光寿命計測装置、及び時間計測方法 - Google Patents

時間計測装置、蛍光寿命計測装置、及び時間計測方法 Download PDF

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JP6946599B1
JP6946599B1 JP2021541093A JP2021541093A JP6946599B1 JP 6946599 B1 JP6946599 B1 JP 6946599B1 JP 2021541093 A JP2021541093 A JP 2021541093A JP 2021541093 A JP2021541093 A JP 2021541093A JP 6946599 B1 JP6946599 B1 JP 6946599B1
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time
signal
measurement
measuring device
tac
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JPWO2022030062A1 (enExample
Inventor
史智 新倉
史智 新倉
歩 吉見
歩 吉見
健 北澤
健 北澤
井上　貴之
貴之 井上
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Hamamatsu Photonics KK
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Hamamatsu Photonics KK
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    • G—PHYSICS
    • G04—HOROLOGY
    • G04F—TIME-INTERVAL MEASURING
    • G04F10/00—Apparatus for measuring unknown time intervals by electric means
    • G—PHYSICS
    • G04—HOROLOGY
    • G04F—TIME-INTERVAL MEASURING
    • G04F10/00—Apparatus for measuring unknown time intervals by electric means
    • G04F10/005—Time-to-digital converters [TDC]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G04—HOROLOGY
    • G04F—TIME-INTERVAL MEASURING
    • G04F10/00—Apparatus for measuring unknown time intervals by electric means
    • G04F10/10—Apparatus for measuring unknown time intervals by electric means by measuring electric or magnetic quantities changing in proportion to time
    • G04F10/105—Apparatus for measuring unknown time intervals by electric means by measuring electric or magnetic quantities changing in proportion to time with conversion of the time-intervals
    • G—PHYSICS
    • G04—HOROLOGY
    • G04F—TIME-INTERVAL MEASURING
    • G04F13/00—Apparatus for measuring unknown time intervals by means not provided for in groups G04F5/00 - G04F10/00
    • G04F13/02—Apparatus for measuring unknown time intervals by means not provided for in groups G04F5/00 - G04F10/00 using optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G01N2021/6415—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence with two excitations, e.g. strong pump/probe flash
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/123—Conversion circuit

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of Unknown Time Intervals (AREA)
JP2021541093A 2020-08-06 2021-05-13 時間計測装置、蛍光寿命計測装置、及び時間計測方法 Active JP6946599B1 (ja)

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JP2021150175A JP7660049B2 (ja) 2020-08-06 2021-09-15 時間計測装置、蛍光寿命計測装置、及び時間計測方法

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JP2020133839 2020-08-06
JP2020133839 2020-08-06
PCT/JP2021/018263 WO2022030062A1 (ja) 2020-08-06 2021-05-13 時間計測装置、蛍光寿命計測装置、及び時間計測方法

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JPWO2022030062A1 JPWO2022030062A1 (enExample) 2022-02-10

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JP2021150175A Active JP7660049B2 (ja) 2020-08-06 2021-09-15 時間計測装置、蛍光寿命計測装置、及び時間計測方法

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US (1) US20230288336A1 (enExample)
EP (1) EP4170436A4 (enExample)
JP (2) JP6946599B1 (enExample)
KR (1) KR20230047328A (enExample)
CN (1) CN115803689A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025004353A1 (ja) * 2023-06-30 2025-01-02 日本電信電話株式会社 測定装置、測定方法、及びプログラム

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5576919A (en) * 1978-12-06 1980-06-10 Japan Spectroscopic Co Measuring method for rapid time division spectroscopic analysis
JPS5972049A (ja) * 1982-10-19 1984-04-23 Horiba Ltd 試料の発光寿命測定装置
JPS59108261U (ja) * 1983-01-08 1984-07-21 株式会社堀場製作所 試料の発光寿命測定装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6690463B2 (en) 2000-02-10 2004-02-10 Evotec Biosystems Ag Fluorescence intensity and lifetime distribution analysis
DE102007026684B4 (de) * 2007-06-08 2009-03-19 Gesellschaft für Schwerionenforschung mbH Zeit-Amplituden-Konverter-Bauelement
EP2199830B1 (en) 2008-12-19 2014-07-02 Leibniz-Institut für Neurobiologie A position resolved measurement apparatus and a method for acquiring space coordinates of a quantum beam incident thereon
JP2010266291A (ja) * 2009-05-13 2010-11-25 Mitsubishi Electric Corp 時間計測回路
CN102545669A (zh) * 2010-12-21 2012-07-04 台达电子工业股份有限公司 具有电容转换功能的太阳能光电系统
CN201926878U (zh) * 2010-12-23 2011-08-10 中国科学院西安光学精密机械研究所 一种光子序列到达时间的连续测量装置
EP2753988B1 (en) * 2011-09-08 2019-10-30 Fastree 3D Bv Time-to-digital converter and method therefor
DE102011055330B4 (de) * 2011-11-14 2024-10-31 Leica Microsystems Cms Gmbh Verfahren zum Messen der Lebensdauer eines angeregten Zustandes in einer Probe
JP5978266B2 (ja) * 2014-09-03 2016-08-24 浜松ホトニクス株式会社 時間計測装置、時間計測方法、発光寿命計測装置、及び発光寿命計測方法
CN109477796B (zh) 2016-05-25 2022-05-31 徕卡显微系统复合显微镜有限公司 允许更高光强度的利用时间相关单光子计数的荧光寿命成像显微学方法
KR102035019B1 (ko) * 2017-09-20 2019-10-22 주식회사 유진로봇 거리 측정 장치, 시간 디지털 변환기, 및 이동체
CN110568749B (zh) * 2019-08-30 2021-04-09 华中师范大学 时间数字转换器电路、装置、设备及装置的控制方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5576919A (en) * 1978-12-06 1980-06-10 Japan Spectroscopic Co Measuring method for rapid time division spectroscopic analysis
JPS5972049A (ja) * 1982-10-19 1984-04-23 Horiba Ltd 試料の発光寿命測定装置
JPS59108261U (ja) * 1983-01-08 1984-07-21 株式会社堀場製作所 試料の発光寿命測定装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025004353A1 (ja) * 2023-06-30 2025-01-02 日本電信電話株式会社 測定装置、測定方法、及びプログラム

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EP4170436A1 (en) 2023-04-26
US20230288336A1 (en) 2023-09-14
CN115803689A (zh) 2023-03-14
JP7660049B2 (ja) 2025-04-10
JPWO2022030062A1 (enExample) 2022-02-10
EP4170436A4 (en) 2024-07-10
KR20230047328A (ko) 2023-04-07
JP2022031264A (ja) 2022-02-18

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