KR20230041708A - 글루코코르티코이드를 함유하는 안구 삽입물 - Google Patents

글루코코르티코이드를 함유하는 안구 삽입물 Download PDF

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Publication number
KR20230041708A
KR20230041708A KR1020237002637A KR20237002637A KR20230041708A KR 20230041708 A KR20230041708 A KR 20230041708A KR 1020237002637 A KR1020237002637 A KR 1020237002637A KR 20237002637 A KR20237002637 A KR 20237002637A KR 20230041708 A KR20230041708 A KR 20230041708A
Authority
KR
South Korea
Prior art keywords
insert
dexamethasone
implant
hydrogel
sustained
Prior art date
Application number
KR1020237002637A
Other languages
English (en)
Korean (ko)
Inventor
찰스 디 블리자드
안키타 데사이
마이클 골드스타인
Original Assignee
오큘라 테라퓨틱스, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오큘라 테라퓨틱스, 인코포레이티드 filed Critical 오큘라 테라퓨틱스, 인코포레이티드
Publication of KR20230041708A publication Critical patent/KR20230041708A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020237002637A 2020-07-16 2021-07-15 글루코코르티코이드를 함유하는 안구 삽입물 KR20230041708A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063052646P 2020-07-16 2020-07-16
US63/052,646 2020-07-16
US202063124176P 2020-12-11 2020-12-11
US63/124,176 2020-12-11
US202163181720P 2021-04-29 2021-04-29
US63/181,720 2021-04-29
PCT/US2021/041761 WO2022015940A1 (en) 2020-07-16 2021-07-15 Ocular insert containing a glucocorticoid

Publications (1)

Publication Number Publication Date
KR20230041708A true KR20230041708A (ko) 2023-03-24

Family

ID=77300995

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237002637A KR20230041708A (ko) 2020-07-16 2021-07-15 글루코코르티코이드를 함유하는 안구 삽입물

Country Status (10)

Country Link
EP (1) EP4181930A1 (zh)
JP (1) JP2023534952A (zh)
KR (1) KR20230041708A (zh)
CN (1) CN116133664A (zh)
AU (1) AU2021309965A1 (zh)
BR (1) BR112023000669A2 (zh)
CA (1) CA3174217A1 (zh)
IL (1) IL299769A (zh)
MX (1) MX2023000628A (zh)
WO (1) WO2022015940A1 (zh)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008044935A (ja) 2006-07-20 2008-02-28 Sicor Inc 固体状無菌活性医薬成分を製造する方法
EP2156823A1 (en) 2008-08-14 2010-02-24 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmeceutical compounds in the form of micro and nanoparticles
EP2396070A4 (en) * 2009-02-12 2012-09-19 Incept Llc ACTIVE COMPOSITION WITH HYDROGEL PLUGS
US11369591B2 (en) 2015-05-12 2022-06-28 Incept, Llc Drug delivery from hydrogels
IL265421B2 (en) * 2016-09-23 2024-04-01 Incept Llc Means for transferring medicine to the anterior chamber in the eye

Also Published As

Publication number Publication date
CA3174217A1 (en) 2022-01-20
WO2022015940A1 (en) 2022-01-20
CN116133664A (zh) 2023-05-16
JP2023534952A (ja) 2023-08-15
MX2023000628A (es) 2023-02-27
EP4181930A1 (en) 2023-05-24
AU2021309965A1 (en) 2023-02-23
BR112023000669A2 (pt) 2023-04-25
IL299769A (en) 2023-03-01

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