JP2023534952A - グルココルチコイドを含む眼内挿入物 - Google Patents

グルココルチコイドを含む眼内挿入物 Download PDF

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Publication number
JP2023534952A
JP2023534952A JP2023502835A JP2023502835A JP2023534952A JP 2023534952 A JP2023534952 A JP 2023534952A JP 2023502835 A JP2023502835 A JP 2023502835A JP 2023502835 A JP2023502835 A JP 2023502835A JP 2023534952 A JP2023534952 A JP 2023534952A
Authority
JP
Japan
Prior art keywords
insert
dexamethasone
sustained release
hydrogel
glucocorticoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023502835A
Other languages
English (en)
Japanese (ja)
Inventor
ブリザード，チャールズ，ディー．
デサイ，アンキタ
ゴールドスタイン，マイケル
Original Assignee
オキュラ セラピューティクス，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オキュラ セラピューティクス，インコーポレイテッド filed Critical オキュラ セラピューティクス，インコーポレイテッド
Publication of JP2023534952A publication Critical patent/JP2023534952A/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2023502835A 2020-07-16 2021-07-15 グルココルチコイドを含む眼内挿入物 Pending JP2023534952A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063052646P 2020-07-16 2020-07-16
US63/052,646 2020-07-16
US202063124176P 2020-12-11 2020-12-11
US63/124,176 2020-12-11
US202163181720P 2021-04-29 2021-04-29
US63/181,720 2021-04-29
PCT/US2021/041761 WO2022015940A1 (en) 2020-07-16 2021-07-15 Ocular insert containing a glucocorticoid

Publications (1)

Publication Number Publication Date
JP2023534952A true JP2023534952A (ja) 2023-08-15

Family

ID=77300995

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023502835A Pending JP2023534952A (ja) 2020-07-16 2021-07-15 グルココルチコイドを含む眼内挿入物

Country Status (10)

Country Link
EP (1) EP4181930A1 (zh)
JP (1) JP2023534952A (zh)
KR (1) KR20230041708A (zh)
CN (1) CN116133664A (zh)
AU (1) AU2021309965A1 (zh)
BR (1) BR112023000669A2 (zh)
CA (1) CA3174217A1 (zh)
IL (1) IL299769A (zh)
MX (1) MX2023000628A (zh)
WO (1) WO2022015940A1 (zh)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008044935A (ja) 2006-07-20 2008-02-28 Sicor Inc 固体状無菌活性医薬成分を製造する方法
EP2156823A1 (en) 2008-08-14 2010-02-24 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmeceutical compounds in the form of micro and nanoparticles
US8409606B2 (en) * 2009-02-12 2013-04-02 Incept, Llc Drug delivery through hydrogel plugs
US11369591B2 (en) 2015-05-12 2022-06-28 Incept, Llc Drug delivery from hydrogels
CA3038075A1 (en) * 2016-09-23 2018-03-29 Incept, Llc Intracameral drug delivery depots

Also Published As

Publication number Publication date
AU2021309965A1 (en) 2023-02-23
MX2023000628A (es) 2023-02-27
IL299769A (en) 2023-03-01
BR112023000669A2 (pt) 2023-04-25
CA3174217A1 (en) 2022-01-20
KR20230041708A (ko) 2023-03-24
CN116133664A (zh) 2023-05-16
EP4181930A1 (en) 2023-05-24
WO2022015940A1 (en) 2022-01-20

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