KR20230029124A - Hand sanitizer hand cream composition - Google Patents

Abstract

The present invention provides a hand sanitizing hand cream composition, wherein the composition supplements the shortcomings of ingredients used in existing hand sanitizers and hand creams and is composed of eco-friendly ingredients, and thus, people with sensitive skin can use the hand cream without any burden of skin irritation, and has the advantage of excellent moisturizing and sterilizing power by adding the ingredients with various functionalities.

Description

Hand sanitizer hand cream composition {Hand sanitizer hand cream composition}

The present invention relates to a hand sanitizing hand cream composition.

In general, hand sanitizers are quasi-drugs that replace hand washing with water, and liquid-type chemical sanitizers or gel-type sanitizers are mainly used, and most of the sanitizers are made of alcohol. This ethanol is very effective for viruses with an envelope composed of a phospholipid layer and protein. It dissolves the envelope of the virus and prevents viruses without an envelope from entering cells even if they die from the outside or enter the host due to lack of an envelope. The ingredients of hand sanitizers usually contain 60 to 80% of ethanol, the main ingredient for disinfection, in addition to propylene glycol (moisturizing effect on the skin), ethylene glycol (solvent), tocopherol (antioxidant), and aloe (fragrance). Ingredients are included.

However, on the contrary to the advantages of fast evaporation of ethanol after use and no residue, there are disadvantages in that hands are relatively dry and skin damage is easy.

Accordingly, glycerin has been added to hand sanitizers to increase moisturizing power, but when synthesized with ethanol, which is the main component of hand sanitizers, it can further dry the skin, resulting in dermatitis called eczema, skin damage, and cell damage.

Republic of Korea Patent Publication 10-2009-0131587

The main object of the present invention is to provide a hand disinfection hand cream composition with excellent moisturizing and sterilizing power using natural extracts.

According to one aspect of the present invention, the present invention provides a hand sanitizing hand cream composition comprising ethanol, carbomer pregel, triethanolamine and distilled water.

In one embodiment of the present invention, the carbomer pregel and ethanol are mixed in a weight ratio of 6:4 to 3:7.

In another embodiment of the present invention, the composition is characterized in that it further comprises 1,2-hexanediol, hyaluronic acid, and jojoba oil.

In another embodiment of the present invention, the 1,2-hexanediol and hyaluronic acid are mixed in a weight ratio of 1:5 to 5:1.

In another embodiment of the present invention, the composition is characterized in that it further comprises at least one selected from the group consisting of rosemary essential oil, wax, vitamin E, and emulsifier.

In another embodiment of the present invention, the composition is characterized in that it further comprises 30 to 50% by weight of ethanol, 15 to 25% by weight of carbomer pregel, 1 to 5% by weight of triethanolamine and the balance distilled water.

As described above, the hand disinfection hand cream composition in the present invention compensates for the disadvantages of the ingredients used in existing hand sanitizers and hand creams and is composed of eco-friendly ingredients so that people with sensitive skin can use it without burden of skin irritation. It has excellent moisturizing and bactericidal power by adding ingredients with various functionalities. In addition, since it has an antibacterial effect, it has various strengths in terms of convenience and cost as well as the excellence of the components of the composition. Finally, since the mental stress caused by COVID-19 can be alleviated using rosemary essential oil, this hand disinfection hand cream composition can be applied not only to products for quarantine but also to various functional cosmetics.

1 is a view showing the configuration of a hand disinfection hand cream composition of the present invention.
2 is a view showing the results of confirming the appearance and gelation of the composition according to the ratio, as a result of confirming the gelation of the hand disinfection hand cream according to the ratio of carbomer free gel and ethanol.
Figure 3 shows the components, contents and pH of the hand disinfecting hand cream composition in an embodiment of the present invention (A), and is a diagram showing the appearance and pH of the final hand disinfecting hand cream composition.
4 is a view showing the results of confirming the 1,2 hexanediol-hyaluronic acid ratio and the moisturizing durability over time.
5 shows the results of measuring the sterilizing power of the hand disinfecting hand cream composition, and shows a photograph (A) of the measuring device before and after using the hand disinfecting hand cream composition and a graph (B) of the sterilizing power before and after using the hand disinfecting hand cream composition.
6 is a view showing the results of confirming the antibacterial effect of the hand disinfection hand cream composition.
7 is a view showing the results of confirming the change in stress index before and after using the hand disinfection hand cream composition.

The present invention relates to a hand disinfection hand cream composition with excellent moisturizing and sterilizing power. Most of the existing products for hand disinfection contain glycerin, but there is a disadvantage that it can dry the skin when mixed with ethanol. Accordingly, the present inventors replaced glycerin with vegetable ethanol to compensate for the above disadvantages, optimizing the ratio of organic low-molecular-weight hyaluronic acid with excellent moisturizing power and carbomer pregel to increase the viscosity of the product. In addition, for hand cream application, natural ingredients such as jojoba oil and 1,2-hexanediol were added to enhance moisturizing power.

It was confirmed that the hand disinfection hand cream composition developed in the present invention complements the disadvantages of existing disinfectants and has excellent sterilization and antibacterial effects as well as moisturizing power by adding a composition based on natural extracts that can be used in hand cream. Furthermore, it was confirmed that the addition of rosemary essential oil, which can obtain the effect of mental and physical stability, is also effective in relieving stress.

In addition, mineral oil, a liquid mixture of petroleum-derived hydrocarbons often used in hand cream applications, clogs pores and causes acne and troubles, is not safe, accelerates skin aging, and sometimes contains carcinogens. Instead of these mineral oils, jojoba oil, a natural oil that relieves inflammation, controls sebum, and prevents skin aging, is added.

Accordingly, the present invention provides a hand sanitizing hand cream composition comprising ethanol, carbomer pregel, triethanolamine and distilled water. The composition preferably contains 30 to 50% by weight of ethanol, 15 to 25% by weight of carbomer pregel, 1 to 5% by weight of triethanolamine and the balance distilled water. If the ethanol is included in less than 30% by weight, antibacterial and antiviral effects may be reduced, and if it exceeds 50% by weight, excessive drying may occur during use. In addition, the carbomer pregel and triethanolamine may be used within the above range to have a viscosity suitable for imparting hand disinfection and moisturizing functions.

In one embodiment of the present invention, the carbomer pregel and ethanol may be mixed in a weight ratio of 6:4 to 3:7. The carbomer pregel and ethanol may be mixed in the above weight range to exhibit a degree of gelation suitable for use in the form of hand cream, and more preferably may be mixed in a weight ratio of 3:7, but are not limited thereto. .

In addition, the composition may further include 1,2-hexanediol, hyaluronic acid, and jojoba oil. The hyaluronic acid is an organic low-molecular-weight hyaluronic acid that is added to replace glycerin, and can impart a moisturizing function to the composition. In addition, the moisturizing function can be further enhanced by adding 1,2-hexanediol and jojoba oil. The composition may include 1,2-hexanediol, hyaluronic acid, and jojoba oil at 1 to 5% by weight of 1,2-hexanediol, 0.1 to 3% by weight of hyaluronic acid, and 3 to 8% by weight of jojoba oil. . In addition, the 1,2-hexanediol and hyaluronic acid are mixed in a weight ratio of 1:5 to 5:1, and can have excellent moisturizing power within the ratio.

As another embodiment of the present invention, the composition may further include rosemary essential oil, wax, vitamin E, an emulsifier, and other additives, and may be included without being limited to the above components as long as they can be included in cosmetics.

The wax may be oliwax LC, olive emulsifying wax, etc., and the emulsifying agent may be sorbitan monostearate, glyceryl stearate, PEG-100 stearate, etc., but is not limited thereto.

The rosemary essential oil is a component capable of obtaining the effect of stabilizing the mind and body, and it was confirmed that it is also effective in relieving stress in an embodiment of the present invention. Therefore, it can be seen that the composition of the hand disinfection hand cream developed through the present invention can be used not only in an epidemic situation such as COVID-19, but also can be applied to various functional cosmetics.

Hereinafter, the present invention will be described in more detail through examples. Since these examples are intended to illustrate the present invention only, the scope of the present invention is not to be construed as being limited by these examples.

[Example]

Example 1. Preparation of hand disinfection hand cream

Carbomer pregel and hyaluronic acid were added to 95% vegetable ethanol for hand disinfection application, respectively, except for glycerin, which is widely used to minimize skin irritation and maintain moisturizing power, to have viscosity and sterilization power. In addition, by using the antiseptic and bactericidal effects of 1,2-hexanediol, the content of ethanol lower than that of conventional hand sanitizers was supplemented, and low-molecular-weight hyaluronic acid was used to increase moisturizing power. First, in order to increase the viscosity, carbomer pregel (22.0%) and triethanolamine (0.44%) were mixed and added in a ratio of 1:2 to increase the viscosity of the composition. Then, in order to mix well the aqueous and oil phases of the composition, Aracel 165, a surfactant of hydrophilic group, and Aracel 60, a surfactant with both lipophilic and hydrophilic properties, were used together, and natural vitamin E was added to penetrate the skin cell membrane. It prevented aging by blocking active oxygen that can occur, and prevented product oxidation by blocking metal ions present in distilled water using EDTA-2Na. Finally, a hand disinfection hand cream composition helpful for emotional relief was prepared by adding 0.2% of natural rosemary essential oil (FIG. 1).

Example 2. Viscosity check according to the ratio of the thickener

The hand sanitizing hand cream composition used carbomer pregel and trietanolamin as thickeners. The reason for using two components as thickeners is that carbomer pregel is acidic and difficult to neutralize. Therefore, the pH was adjusted so that the thickener became neutral by adding trietanolamin. Therefore, the ratio of carbomer pregel and trietanolamin was mixed at a ratio of 1:2, respectively, and mixed using a stirrer. When ethanol was additionally added after mixing, it was confirmed that gelation occurred in all but 2:8 when the ratios were 2:8, 3:7, 4:6, 5:5, and 6:4, respectively (Fig. 2A ). All but 2:8 were gelated, but in order to adjust the viscosity of the hand sanitizer to the hand cream composition, the ethanol content was high and the gelation ratio of 3:7 was selected (FIG. 2B).

Example 3. pH confirmation of hand disinfection hand cream ingredients

pH measurement was conducted to prepare hand disinfection hand cream with less skin irritation. If the pH is low, it is highly acidic and can cause skin damage. If the pH is high, the bactericidal power is weakened and the protein can be damaged when in contact with the skin. It is important to stay within 7 range. Therefore, each component was measured with a pH instrument (ORION STAR A211, USA) to show the pH of the product as an award together with the components and contents of the hand disinfection hand cream composition (FIG. 3A), and finally prepared hand disinfection hand cream composition It was confirmed that showed pH 6.7, which is an appropriate use range (FIG. 3B).

Example 4. Confirmation of moisturizing power of hand disinfection hand cream

To check the moisturizing power of the hand disinfection hand cream composition, the ratios of 1,2-hexanediol and hyaluronic acid were 0:6, 1:5, 2:4, 3:3, 4:2, 5:1, and 6:0, respectively. Based on a total of 7 samples, the moisturizing power of the inner part of the upper arm was measured for 3 adults in their 20s. A moisture meter (Corneometer CM825, UK) was used to measure skin hydration persistence. It measures the electrostatic load capacity of the current conducted through the electrode gap adhered to the skin surface. Since the moisture content of the skin and the electrostatic load capacity are proportional to each other, The principle that the higher the moisture level of the skin, the higher the value appears.

After applying to the inner part of the upper arm, a square skin surface of 4 x 4 cm2, the skin moisture content was measured at an average temperature of 22.24 ° C and an average humidity of 52.6% at 0, 1, 2, 3, and 4 hour units and by each ratio. As a result of the analysis, as shown in FIG. 4, it was confirmed that the ratio of 1,2-hexanediol to hyaluronic acid of 5:1 had a relatively excellent moisturizing effect.

Example 5. Confirmation of sterilization power of hand disinfection hand cream

A portable ATP meter (TBD-1000, Korea) was used to measure the sterilizing power of the hand sanitizer hand cream composition. The measured value is the measured value before and after using the Clean Gel Hand Cream, and the measured value after evenly rubbing the reagent rod for surface measurement on the palm area of 10 x 10cm2 area RLU (Relative Light Unit) and Clean Gel Hand RLU after application of the cream was compared (Fig. 5A). As shown in the graph measured for 3 people in this way, it was confirmed that the average contamination value was significantly reduced from 323 to 60.3, indicating that the sterilization power was excellent (FIG. 5B). In addition, in order to confirm the antibacterial effect, Staphylococcus aureus was cultured on a solid medium at 37 ° C for 24 hours using an incubator (SI-300R, Korea), and the results are shown in pictures (FIG. 6). Before using the hand disinfection hand cream composition, it was confirmed that the number of bacteria increased after 24 hours, and after use, no bacteria appeared at all, so it was confirmed that there was a strong antibacterial effect.

Example 6. Confirmation of stress relieving effect of hand disinfection hand cream

In order to measure the emotional stress relief effect of the hand disinfectant hand cream composition containing rosemary essential oil, a natural extract, the cumulative stress index of the control group and the experimenters was measured using a stress meter (UBio Macpa, Korea). After applying the hand disinfection hand cream composition to each experimenter's hand, inhaling the fragrance through the nose, the cumulative stress index was measured 5 and 20 minutes later. As a result of the analysis, the cumulative stress index of the control group that did not inhale the fragrance hardly changed from 49 to 46, but experimenter 1 decreased from 48 to 40, experimenter 2 decreased from 46 to 30, and experimenter 3 decreased from 27 to 22. As a result, it was confirmed that the hand disinfection hand cream composition was effective in relieving emotional stress by confirming that the difference between the control group and the experimenter occurred (FIG. 7).

Claims (6)

A hand sanitizing hand cream composition comprising ethanol, carbomer pregel, triethanolamine and distilled water.
According to claim 1,
The carbomer pregel and ethanol are mixed in a weight ratio of 6: 4 to 3: 7, hand disinfection hand cream composition.
According to claim 1,
The composition further comprises 1,2-hexanediol, hyaluronic acid, and jojoba oil, hand disinfection hand cream composition. According to claim 1,
The 1,2-hexanediol and hyaluronic acid are mixed in a weight ratio of 1:5 to 5:1, hand disinfection hand cream composition.
According to claim 3,
The composition further comprises at least one selected from the group consisting of rosemary essential oil, wax, vitamin E, and emulsifier, hand sanitizing hand cream composition.
According to claim 1,
The composition further comprises 30 to 50% by weight of ethanol, 15 to 25% by weight of carbomer pregel, 1 to 5% by weight of triethanolamine and the balance of distilled water, hand sanitizing hand cream composition.

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