KR20090131587A - Disinfectant composition for hand including mastic - Google Patents

Abstract

PURPOSE: A hand disinfection composition containing mastic and ethanol is provided to prevent helicobactor pyroli infection without rinsing with water. CONSTITUTION: A hand disinfection composition contains mastic oil and ethanol. The composition contains 0.1-5 weight% of mastic oil, 40-80 weight% of ethanol, 0.1-2 weight% of moisturizer selected among glycerin, hyaluronic sodium or aloe extract, 0.1-5 weight% of carbomer, 0.05-2.5 weight% of triethylamine, 0.1-4 weight% surfactant, and remaining amount of water.

Description

Disinfectant composition for hand including mastic}

The present invention is Helicobacter pylori ( Helicobactor) that is the causative agent of gastric ulcer and duodenal ulcer pyroli ) has a bactericidal effect, but also relates to a hand sanitizer composition which has excellent feeling and does not need to be washed out with water.

Mastic is a sap extracted from Pistasia lentiscus , a kind of pistachio tree growing on the island of Chios, Greece. Mastic has long been shown to have the effect of inhibiting or killing the growth of Helicobactor pyroli , known as the causative agent of gastritis, gastric ulcer and duodenal ulcer. It is also known to have the effect of inhibiting or killing the growth of Escherichia coli and Staphylococcus aureus causing food poisoning.

These germs can be infected through breathing or physical contact among people, through food or in livestock, in unhygienic conditions. Among the paths of infection, infection is easy through the hands. In order to block the path of infection, hand sanitizers having various active ingredients have been developed. However, the hand disinfectant products such as soaps and antibacterial hand washes that are commercially available only suppress general bacteria, and there is no product that can prevent the infection of Helicobacter pylori, and it is a hassle to form a bubble and wash with water after use. There is this.

On the other hand, in the case of mastic oil, due to the physical properties of the mastic oil, it is not easy to use a conventional composition formulation as a hand sanitizer, and it is necessary to improve the feeling due to poor touch.

Therefore, the technical problem to be achieved by the present invention is to provide a disinfectant composition having a bactericidal effect against the common bacteria, as well as Helicobacter pylori, the causative agent of gastric ulcer and duodenal ulcer.

Another technical problem to be achieved by the present invention is to provide a hand disinfectant composition that not only has a bactericidal effect on Helicobacter pylori, but also has excellent usability and does not need to be washed out with water.

In order to achieve the above technical problem, the present invention provides a hand sanitizer composition containing mastic (mastic) oil and ethanol.

More preferably, the present invention is a mastic oil; ethanol; Surfactants; Carbomer; Any one or more carbomer neutralizers selected from the group consisting of sodium hydroxide, potassium hydroxide, ammonium hydroxide and triethanolamine; Humectants; And it provides a hand sanitizer composition characterized in that it contains water.

In the hand sanitizer composition of the present invention, the surfactant may be polysorbate; Polyoxyl hydrogenated castor oil; Alkyl sodium sulfates such as sodium lauryl sulfate and sodium myristyl sulfate; Sodium N-acyl sarcosinate, such as sodium N-Lauroyl sarcosinate and sodium N-myristyl sarcosinate; Fatty acid esters; Polyoxy ethylene cured castor oil; Polyoxyethylene higher alcohol ethers; Polyoxy ethylene polyoxy propylene copolymers; Polyoxy ethylene polypropylene fatty acid esters and the like can be used alone or in combination, and using a mixture of polysorbate and polyoxyl hydrogenated castor oil in terms of feeling when used in combination with mastic oil and ethanol, which are related to sterilization It is preferable.

In addition, the hand disinfectant composition of the present invention includes a viscosity modifier to impart a suitable viscosity for forming and using a formulation, and among the various viscosity modifiers, carbomer is most preferable in terms of mixing and feeling with mastic oil. .

The hand disinfectant composition of the present invention also includes a carbomer neutralizing agent to assist in the viscosity formation of such carbomer, and as such a neutralizing agent, sodium hydroxide, potassium hydroxide, ammonium hydroxide, triethanolamine, or the like may be used alone or in combination. Preferably, triethanolamine is the most preferable from a viewpoint of usability and the like.

Thus, preferably, the present invention is a mastic oil; ethanol; Humectants; Carbomer; Triethanolamine, a carbomer neutralizer; Surfactants; And it provides a hand sanitizer composition comprising water.

In this composition, as mentioned above, a mixture of polysorbate and polyoxyl hydrogenated castor oil is preferred as the surfactant.

In the hand sanitizer composition of the present invention, as a moisturizing agent, glycerin, sodium hyaluronate, aloe extract and the like may be used alone or in combination.

Preferably, the hand sanitizer composition of the present invention comprises 0.1-5% by weight of mastic oil relative to the total weight of the composition; Ethanol 40-80 wt%; 0.1-2% by weight of at least one moisturizer selected from the group consisting of glycerin, sodium hyaluronate and aloe extract; Carbomer 0.1-5% by weight; 0.05-2.5 wt% triethylamine; 0.1-4% by weight of surfactant; And a balance of water, more preferably, the composition contains 0.2-1% by weight carbomer and 0.1-0.5% by weight triethanolamine relative to the total weight of the composition.

In the hand sanitizer composition of the present invention, the content of the mastic oil is preferably 0.01-10% by weight, more preferably 0.1-5% by weight, based on the total weight of the hand sanitizer composition. If it contains less than 0.1% by weight of mastic oil, the sterilization power is lowered. If it is contained in more than 5% by weight, the content of mastic oil is high, so it is not only strong smell of the mastic, but also a feeling of excess oil content, which reduces the sterilization power, In consideration of the easy disinfectant formulation formation, ease of use, etc., the content is more preferably 0.1-5% by weight.

In the hand sanitizer composition of the present invention, the content of ethanol serving as a bactericide is preferably 30-90% by weight, more preferably 40-80% by weight based on the total weight of the hand sanitizer composition. If the ethanol content is less than 40% by weight, the sterilization power is lowered. If the content of ethanol is more than 80% by weight, the ethanol content is high, which not only irritates the skin but also gives strong resistance to alcohol odor. In consideration of ease of use, ease of use, etc., the content is more preferably 40-80% by weight.

The hand sanitizer composition of the present invention is a component for giving a soft, foreign-free feeling, and includes a carbomer which is a viscosity adjusting agent and a neutralizing agent which neutralizes the viscosity adjusting agent to form a viscosity. The content of such carbomer and neutralizing agent is preferably 0.1-5% by weight and 0.05-2.5% by weight, respectively. When the carbomer, which is a viscosity modifier, is contained in an amount less than 0.1% by weight, a suitable formulation is not formed, and a viscosity suitable for use is not formed.

In particular, each component constituting the hand sanitizer composition of the present invention has the advantage of forming a viscosity that gives a good feeling when forming and using the formulation when the content ratio is formed, there is an advantage that the foreign body is not felt during use.

The hand sanitizer composition of the present invention may include additional components such as a flavoring agent, a coloring agent, etc. within the scope of not impairing the object of the present invention, but is not limited thereto.

The present invention provides a hand disinfectant composition which is effective in preventing infection of Helicobacter pylori as well as general bacteria, and has excellent feeling and does not need to rinse with water.

Hereinafter, examples and the like will be described in detail to help understand the present invention. However, embodiments according to the present invention can be modified in many different forms, the scope of the invention should not be construed as limited to the following examples. Embodiments of the present invention are provided to more fully describe the present invention to those skilled in the art.

Preparation of Example 1-8

A hand sanitizer composition was prepared according to Table 1 below. Carbomer was dissolved in purified water, a solution of ethanol, polysorbate, polyoxyl hydrogenated castor oil, and mastic oil was added and dissolved, followed by triethanolamine to form a viscosity. It was prepared by adding and stirring sodium hyaluronate, aloe extract, fragrance and the like.

Ingredient (% by weight) Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 ethanol 60.0 60.0 60.0 60.0 60.0 60.0 60.0 60.0 glycerin 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 Hyaluronic Sodium 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 Aloe extract 0.10 0.10 0.10 0.10 0.10 0.10 0.10 0.10 Carbomer 0.0001 0.01 0.1 0.28 1.0 2.0 3.0 5.0 Triethanolamine 0.00005 0.005 0.05 0.10 0.5 1.0 1.5 2.5 Mastic Oil 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Polysorbate 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Polyoxyl Hydrogenated Castor Oil 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Flavor 0.04 0.04 0.04 0.04 0.04 0.04 0.04 0.04 Purified water Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity

In Examples 1-8 of Table 1, the content of the carbomer and the neutralizing agent triethanolamine, which is a viscosity modifier, was different, which is a comparative evaluation experiment for preparing a good-feel formulation.

Experimental Example 1 Appearance Evaluation of Examples 1-8

The degree to which the viscosity was formed visually was evaluated for the composition prepared in Example 1-8. The results are shown in Table 2 below.

Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 Status display + + ++ +++ +++ +++ +++ +++

In Table 2, +++ is a state in which a suitable viscosity is formed to form a hand sanitizer formulation, ++ is a state in which a little viscosity is formed, + means a state in which the viscosity is not suitable to form a hand sanitizer formulation do.

As shown in Table 2 above, Examples 3-8 have the appropriate viscosity to form a hand sanitizer formulation, the results can be prepared in a commercially available formulation.

Experimental Example 2 Sensory Evaluation of Examples 3-8

Sensory evaluation of the feeling of use was made through the viscosity of the composition of Example 3-8, which can be equipped with the formulation of the hand disinfectant, and the foreign matter remaining after use, thereby confirming the proper amount of the viscosity modifier and the neutralizing agent.

The viscosity and the foreign matter at the time of use of the hand sanitizer composition of Example 3-8 were evaluated and the results are shown in Table 3 below. Twenty healthy adults were evaluated. The degree of feeling was divided into three stages.

Kinds Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 Viscosity C B B A A A Foreign body D D E F F F

In Table 3, A indicates 'high viscosity' when used, B indicates 'good viscosity', and C indicates 'low viscosity'. In addition, D denotes 'no foreign matter', E denotes 'a little foreign matter', and F denotes 'a lot of foreign matter'.

As a result of sensory evaluation on the feeling of use, which varies depending on the content of the viscosity modifier and the neutralizing agent, carbomer and triethanolamine, when the carbomer exceeds 5% by weight, the viscosity is high and the foreign substance remains in the hands when used. Devalued. As a result, Example 4-5 had a good viscosity, and Example 4 showed the best result in the sensory evaluation for foreign matter.

Claims (5)

Hand disinfectant composition containing mastic oil and ethanol. The composition of claim 1, wherein the composition comprises a surfactant; Carbomer; Any one or more carbomer neutralizers selected from the group consisting of sodium hydroxide, potassium hydroxide, ammonium hydroxide and triethanolamine; Humectants; And water disinfectant composition, characterized in that it further contains water. 3. The hand disinfectant composition of claim 2, wherein the carbomer neutralizer is triethanolamine. The composition of claim 2, wherein the composition comprises 0.1-5% by weight of mastic oil, relative to the total weight of the composition; Ethanol 40-80 wt%; 0.1-2% by weight of at least one moisturizer selected from the group consisting of glycerin, sodium hyaluronate and aloe extract; Carbomer 0.1-5% by weight; 0.05-2.5 wt% triethylamine; 0.1-4% by weight of surfactant; And a residual amount of water. The hand disinfectant composition according to claim 4, wherein the composition contains 0.2-1% by weight of carbomer and 0.1-0.5% by weight of triethanolamine relative to the total weight of the composition.