KR20230025941A - 비-erk mapk 경로 억제제-내성 암을 치료하기 위한 방법 및 조성물 - Google Patents

비-erk mapk 경로 억제제-내성 암을 치료하기 위한 방법 및 조성물 Download PDF

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KR20230025941A
KR20230025941A KR1020237004648A KR20237004648A KR20230025941A KR 20230025941 A KR20230025941 A KR 20230025941A KR 1020237004648 A KR1020237004648 A KR 1020237004648A KR 20237004648 A KR20237004648 A KR 20237004648A KR 20230025941 A KR20230025941 A KR 20230025941A
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bvd
braf
inhibitor
cancer
cells
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사우라브 사하
딘 웰쉬
개리 데크레스센조
제프리 제임스 로익스
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바이오메드 밸리 디스커버리즈, 인코포레이티드
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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KR1020237004648A 2013-12-20 2017-05-22 비-erk mapk 경로 억제제-내성 암을 치료하기 위한 방법 및 조성물 Ceased KR20230025941A (ko)

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Application Number Priority Date Filing Date Title
US201361919551P 2013-12-20 2013-12-20
US15/161,137 2016-05-20
US15/161,137 US20160317519A1 (en) 2013-12-20 2016-05-20 Methods and compositions for treating non-erk mapk pathway inhibitor-resistant cancers
PCT/US2017/033843 WO2017201532A1 (en) 2013-12-20 2017-05-22 Methods and compositions for treating non-erk mapk pathway inhibitor-resistant cancers
KR1020187037187A KR20190009804A (ko) 2013-12-20 2017-05-22 비-erk mapk 경로 억제제-내성 암을 치료하기 위한 방법 및 조성물

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KR1020187037187A Ceased KR20190009804A (ko) 2013-12-20 2017-05-22 비-erk mapk 경로 억제제-내성 암을 치료하기 위한 방법 및 조성물

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EP3458056A1 (en) 2019-03-27
WO2015095842A3 (en) 2015-08-20
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JP2024133638A (ja) 2024-10-02
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US20180104228A1 (en) 2018-04-19
IL263108A (en) 2018-12-31
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AU2017267804B2 (en) 2023-04-27
MX2018014231A (es) 2019-05-15
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US20190201387A1 (en) 2019-07-04
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JP2022034068A (ja) 2022-03-02
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