KR20230014694A - 항원-코딩 카세트 - Google Patents

항원-코딩 카세트 Download PDF

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Publication number
KR20230014694A
KR20230014694A KR1020227040441A KR20227040441A KR20230014694A KR 20230014694 A KR20230014694 A KR 20230014694A KR 1020227040441 A KR1020227040441 A KR 1020227040441A KR 20227040441 A KR20227040441 A KR 20227040441A KR 20230014694 A KR20230014694 A KR 20230014694A
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South Korea
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sequence
nucleic acid
antigen
epitope
encoding nucleic
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Korean (ko)
Inventor
카린 주스
에이미 레이첼 라파포트
시아란 다니엘 스캘란
레오니드 기틀린
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그릿스톤 바이오, 인코포레이티드
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
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    • A—HUMAN NECESSITIES
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    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
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    • C12N2770/36011—Togaviridae
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020227040441A 2020-04-21 2021-04-21 항원-코딩 카세트 Pending KR20230014694A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063013466P 2020-04-21 2020-04-21
US63/013,466 2020-04-21
PCT/US2021/028485 WO2021216775A2 (en) 2020-04-21 2021-04-21 Antigen-encoding cassettes

Publications (1)

Publication Number Publication Date
KR20230014694A true KR20230014694A (ko) 2023-01-30

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KR1020227040441A Pending KR20230014694A (ko) 2020-04-21 2021-04-21 항원-코딩 카세트

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US (1) US20230310563A1 (https=)
EP (1) EP4138890A4 (https=)
JP (1) JP2023523413A (https=)
KR (1) KR20230014694A (https=)
CN (1) CN115803049A (https=)
AU (1) AU2021258191A1 (https=)
CA (1) CA3173905A1 (https=)
IL (1) IL296854A (https=)
WO (1) WO2021216775A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025028960A1 (ko) * 2023-07-28 2025-02-06 주식회사 엘지화학 항원 전달용 컨쥬게이트 및 이의 이용

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019013259A (es) 2017-05-08 2020-01-13 Gritstone Oncology Inc Vectores de neoantigeno de alfavirus.
MX2021014525A (es) 2019-05-30 2022-03-17 Gritstone Bio Inc Adenovirus modificados.
KR20230046313A (ko) 2020-08-06 2023-04-05 그릿스톤 바이오, 인코포레이티드 다중에피토프 백신 카세트

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
US6514731B1 (en) * 1996-05-24 2003-02-04 Chiron Corporation Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
JP2002536008A (ja) * 1999-02-11 2002-10-29 ジェンザイム・コーポレーション 抗原ペプチドコンカテマー
CA2394741A1 (en) * 1999-12-21 2001-06-28 Epimmune Inc. Inducing cellular immune responses to prostate cancer antigens using peptide and nucleic acid compositions
MX2007015933A (es) * 2005-06-17 2008-04-21 Mannkind Corp Metodos y composiciones para generar respuestas inmunes multivalentes contra espitopes dominantes y subdominantes, expresados en celulas cancerigenas y estromas tumorales.
CN101721698B (zh) * 2008-10-24 2014-04-02 法罗斯疫苗公司 抗口蹄疫疫苗组合物及其制备和应用
CA2828068C (en) * 2011-02-22 2019-03-19 Biondvax Pharmaceuticals Ltd. Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines
AU2017226199A1 (en) * 2016-03-04 2018-09-13 New York University Virus vectors expressing multiple epitopes of tumor associated antigens for inducing antitumor immunity
CN112368386A (zh) * 2018-05-23 2021-02-12 磨石肿瘤生物技术公司 共有抗原
CN110003314B (zh) * 2019-04-11 2023-06-09 上海市计划生育科学研究所 H1n1流感病毒血凝素可诱发广谱保护性抗体的表位肽及其应用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025028960A1 (ko) * 2023-07-28 2025-02-06 주식회사 엘지화학 항원 전달용 컨쥬게이트 및 이의 이용

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WO2021216775A3 (en) 2021-12-16
EP4138890A2 (en) 2023-03-01
US20230310563A1 (en) 2023-10-05
AU2021258191A1 (en) 2022-12-01
JP2023523413A (ja) 2023-06-05
CA3173905A1 (en) 2021-10-28
WO2021216775A2 (en) 2021-10-28
EP4138890A4 (en) 2024-07-31
CN115803049A (zh) 2023-03-14
IL296854A (en) 2022-11-01

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