KR20220160602A - 해마 위축을 검출하기 위한 키트 또는 디바이스 및 방법 - Google Patents

해마 위축을 검출하기 위한 키트 또는 디바이스 및 방법 Download PDF

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KR20220160602A
KR20220160602A KR1020227034809A KR20227034809A KR20220160602A KR 20220160602 A KR20220160602 A KR 20220160602A KR 1020227034809 A KR1020227034809 A KR 1020227034809A KR 20227034809 A KR20227034809 A KR 20227034809A KR 20220160602 A KR20220160602 A KR 20220160602A
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mir
hsa
gene
seq
polynucleotide
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치오리 카시무라
히로코 스도
마키코 요시모토
슘페이 니이다
켄고 이토
다이치 시게미즈
타카시 카토
아키노리 나카무라
Original Assignee
도레이 카부시키가이샤
고꾸리쯔 켄큐카이하츠호진 고꾸리쯔 장수의료 연구센터
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Application filed by 도레이 카부시키가이샤, 고꾸리쯔 켄큐카이하츠호진 고꾸리쯔 장수의료 연구센터 filed Critical 도레이 카부시키가이샤
Publication of KR20220160602A publication Critical patent/KR20220160602A/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020227034809A 2020-03-31 2021-03-31 해마 위축을 검출하기 위한 키트 또는 디바이스 및 방법 Withdrawn KR20220160602A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020064383 2020-03-31
JPJP-P-2020-064383 2020-03-31
PCT/JP2021/013807 WO2021201092A1 (ja) 2020-03-31 2021-03-31 海馬萎縮を検出するためのキット又はデバイス及び方法

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KR20220160602A true KR20220160602A (ko) 2022-12-06

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KR1020227034809A Withdrawn KR20220160602A (ko) 2020-03-31 2021-03-31 해마 위축을 검출하기 위한 키트 또는 디바이스 및 방법

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Country Link
US (1) US20230212675A1 (https=)
EP (1) EP4130259A4 (https=)
JP (1) JPWO2021201092A1 (https=)
KR (1) KR20220160602A (https=)
CN (1) CN115485378A (https=)
CA (1) CA3178889A1 (https=)
WO (1) WO2021201092A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4498086A3 (en) 2018-02-13 2025-04-02 Toray Industries, Inc. Kit or device and method for detecting dementia

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140272993A1 (en) 2013-03-15 2014-09-18 The Translational Genomics Research Institute Method of sequencing a full microrna profile from cerebrospinal fluid
JP2017184642A (ja) 2016-04-01 2017-10-12 株式会社ヘルシーパス 認知症マーカー、それを用いた認知症の評価方法、評価試薬および評価キット
WO2019014457A1 (en) 2017-07-12 2019-01-17 Texas Tech University System MICROARN-455-3P AS A PERIPHERAL BIOMARKER OF ALZHEIMER'S DISEASE
WO2019048500A1 (en) 2017-09-05 2019-03-14 Amoneta Diagnostics NON-CODING RNA (RNANC) FOR THE DIAGNOSIS OF COGNITIVE DISORDERS
US20190136320A1 (en) 2016-04-25 2019-05-09 Instytut Biologii Doswiadczalnej Im. Marcelego Nenckiego Polska Akademia Nauk Microrna biomarkers in blood for diagnosis of alzheimer's disease
US20190249250A1 (en) 2015-11-20 2019-08-15 Braindtech S.R.L. Microglia Microvesicles Contained MicroRNA-Based Methods For The Diagnosis, Prognosis And Treatment Monitoring Of Neurological, Neurodegenerative And Inflammation-Based Diseases
WO2019159884A1 (ja) 2018-02-13 2019-08-22 東レ株式会社 認知症の検出のためのキット又はデバイス及び方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013374345A1 (en) * 2013-01-17 2015-08-06 Moderna Therapeutics, Inc. Signal-sensor polynucleotides for the alteration of cellular phenotypes
US10620228B2 (en) * 2014-06-18 2020-04-14 Toray Industries, Inc. Lung cancer detection kit or device, and detection method
JP7165329B2 (ja) * 2017-04-28 2022-11-04 東レ株式会社 卵巣腫瘍の検出のためのキット、デバイス及び方法
CN110799648B (zh) * 2017-06-29 2024-03-22 东丽株式会社 用于检测肺癌的试剂盒、装置和方法
JP7045970B2 (ja) 2018-10-16 2022-04-01 三菱重工業株式会社 リスク特定装置、リスク特定方法、およびプログラム

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140272993A1 (en) 2013-03-15 2014-09-18 The Translational Genomics Research Institute Method of sequencing a full microrna profile from cerebrospinal fluid
US20190249250A1 (en) 2015-11-20 2019-08-15 Braindtech S.R.L. Microglia Microvesicles Contained MicroRNA-Based Methods For The Diagnosis, Prognosis And Treatment Monitoring Of Neurological, Neurodegenerative And Inflammation-Based Diseases
JP2017184642A (ja) 2016-04-01 2017-10-12 株式会社ヘルシーパス 認知症マーカー、それを用いた認知症の評価方法、評価試薬および評価キット
US20190136320A1 (en) 2016-04-25 2019-05-09 Instytut Biologii Doswiadczalnej Im. Marcelego Nenckiego Polska Akademia Nauk Microrna biomarkers in blood for diagnosis of alzheimer's disease
WO2019014457A1 (en) 2017-07-12 2019-01-17 Texas Tech University System MICROARN-455-3P AS A PERIPHERAL BIOMARKER OF ALZHEIMER'S DISEASE
WO2019048500A1 (en) 2017-09-05 2019-03-14 Amoneta Diagnostics NON-CODING RNA (RNANC) FOR THE DIAGNOSIS OF COGNITIVE DISORDERS
WO2019159884A1 (ja) 2018-02-13 2019-08-22 東レ株式会社 認知症の検出のためのキット又はデバイス及び方法

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Bhagat R. et al., Cell Death Differ., 2018 Nov,: (10): 1837-1854
Daniel H. S. et al., The Journal of Nuclear Medicine, 2004 Apr, vol.45, No.4
Emrah Duzel et al., Alzhemer's & Dementia Monitoring, 2018, 10, 782-790
Grasso M. et al., Neurobiol. Aging., 2019 Dec; 84: 240.e1-240.e12.
Kumar S. et al., Hum. Mol. Genet., 2017 Oct, 1; 26(19): 3808-3822
Nakamura A. et al., Nature, 2018 Jan 31, vol.554, p.249-254

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CA3178889A1 (en) 2021-10-07
EP4130259A4 (en) 2024-07-10
US20230212675A1 (en) 2023-07-06
EP4130259A1 (en) 2023-02-08
WO2021201092A1 (ja) 2021-10-07
JPWO2021201092A1 (https=) 2021-10-07
CN115485378A (zh) 2022-12-16

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