CN115485378A - 用于检测海马萎缩的试剂盒或器件以及方法 - Google Patents

用于检测海马萎缩的试剂盒或器件以及方法 Download PDF

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Publication number
CN115485378A
CN115485378A CN202180026096.7A CN202180026096A CN115485378A CN 115485378 A CN115485378 A CN 115485378A CN 202180026096 A CN202180026096 A CN 202180026096A CN 115485378 A CN115485378 A CN 115485378A
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China
Prior art keywords
mir
hsa
gene
polynucleotide
seq
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Pending
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CN202180026096.7A
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English (en)
Chinese (zh)
Inventor
柏村智织
须藤裕子
吉本真纪子
新饭田俊平
伊藤健吾
重水大智
加藤隆司
中村昭范
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National Center for Geriatrics and Gerontology
Toray Industries Inc
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National Center for Geriatrics and Gerontology
Toray Industries Inc
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Application filed by National Center for Geriatrics and Gerontology, Toray Industries Inc filed Critical National Center for Geriatrics and Gerontology
Publication of CN115485378A publication Critical patent/CN115485378A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202180026096.7A 2020-03-31 2021-03-31 用于检测海马萎缩的试剂盒或器件以及方法 Pending CN115485378A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020064383 2020-03-31
JP2020-064383 2020-03-31
PCT/JP2021/013807 WO2021201092A1 (ja) 2020-03-31 2021-03-31 海馬萎縮を検出するためのキット又はデバイス及び方法

Publications (1)

Publication Number Publication Date
CN115485378A true CN115485378A (zh) 2022-12-16

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CN202180026096.7A Pending CN115485378A (zh) 2020-03-31 2021-03-31 用于检测海马萎缩的试剂盒或器件以及方法

Country Status (7)

Country Link
US (1) US20230212675A1 (https=)
EP (1) EP4130259A4 (https=)
JP (1) JPWO2021201092A1 (https=)
KR (1) KR20220160602A (https=)
CN (1) CN115485378A (https=)
CA (1) CA3178889A1 (https=)
WO (1) WO2021201092A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4498086A3 (en) 2018-02-13 2025-04-02 Toray Industries, Inc. Kit or device and method for detecting dementia

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140200261A1 (en) * 2013-01-17 2014-07-17 Moderna Therapeutics, Inc. Signal-sensor polynucleotides for the alteration of cellular phenotypes
CN106471132A (zh) * 2014-06-18 2017-03-01 东丽株式会社 肺癌的检测试剂盒或装置以及检测方法
JP2017184642A (ja) * 2016-04-01 2017-10-12 株式会社ヘルシーパス 認知症マーカー、それを用いた認知症の評価方法、評価試薬および評価キット
WO2019159884A1 (ja) * 2018-02-13 2019-08-22 東レ株式会社 認知症の検出のためのキット又はデバイス及び方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140272993A1 (en) 2013-03-15 2014-09-18 The Translational Genomics Research Institute Method of sequencing a full microrna profile from cerebrospinal fluid
ITUB20155765A1 (it) 2015-11-20 2017-05-20 Braindtech S R L Metodi per diagnosi, prognosi e monitoraggio terapeutico di patologie neurologiche, neurodegenerative e infiammatorie basati su microRNA contenuto in microvescicole microglia
EP3449009B1 (en) 2016-04-25 2021-08-18 Instytut Biologii Doswiadczalnej PAN. im. M. Nenckiego Microrna biomarkers in blood for diagnosis of alzheimer's disease
JP7165329B2 (ja) * 2017-04-28 2022-11-04 東レ株式会社 卵巣腫瘍の検出のためのキット、デバイス及び方法
CN110799648B (zh) * 2017-06-29 2024-03-22 东丽株式会社 用于检测肺癌的试剂盒、装置和方法
US11492669B2 (en) 2017-07-12 2022-11-08 Texas Tech University System MicroRNA-455-3p as a peripheral biomarker for Alzheimer's disease
EP3679157B1 (en) 2017-09-05 2024-12-18 Amoneta Diagnostics Non-coding rnas (ncrna) for the diagnosis of cognitive disorders
JP7045970B2 (ja) 2018-10-16 2022-04-01 三菱重工業株式会社 リスク特定装置、リスク特定方法、およびプログラム

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140200261A1 (en) * 2013-01-17 2014-07-17 Moderna Therapeutics, Inc. Signal-sensor polynucleotides for the alteration of cellular phenotypes
CN106471132A (zh) * 2014-06-18 2017-03-01 东丽株式会社 肺癌的检测试剂盒或装置以及检测方法
JP2017184642A (ja) * 2016-04-01 2017-10-12 株式会社ヘルシーパス 認知症マーカー、それを用いた認知症の評価方法、評価試薬および評価キット
WO2019159884A1 (ja) * 2018-02-13 2019-08-22 東レ株式会社 認知症の検出のためのキット又はデバイス及び方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ABULAISH ANSARI 等: ""miR-146a and miR-181a are involved in the progression of mild cognitive impairment to Alzheimer\'s disease"", NEUROBIOLOGY OF AGING, vol. 82, 21 June 2019 (2019-06-21), pages 105 *
江坤鸿 等: ""基于microRNA差异表达的精神分裂症与抑郁症共病研究"", 解放军医学杂志, vol. 42, no. 4, 1 April 2017 (2017-04-01), pages 336 - 341 *

Also Published As

Publication number Publication date
CA3178889A1 (en) 2021-10-07
EP4130259A4 (en) 2024-07-10
US20230212675A1 (en) 2023-07-06
KR20220160602A (ko) 2022-12-06
EP4130259A1 (en) 2023-02-08
WO2021201092A1 (ja) 2021-10-07
JPWO2021201092A1 (https=) 2021-10-07

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Application publication date: 20221216